hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14677.1
Complex Portal: CPX-21168
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NAA80 | N-alpha-acetyltransferase 80 (HsNAAA80) (EC 2.3.1.-) (N-acetyltransferase 6) (Protein fusion-2) (Protein fus-2) | 5 | UniProt NCBI |
| PFN2 | Profilin-2 (Profilin II) | 5 | UniProt NCBI |
| NKX2-5 | Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E) | 5 | UniProt NCBI |
| SESN1 | Sestrin-1 (EC 1.11.1.-) (p53-regulated protein PA26) | 5 | UniProt NCBI |
| PFN1 | Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3680 | 0.00998567643899 | 0.4 | PFN2 PFN1 | Physico chemical features and toxicity associated pathways |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NAA80 | PFN2 | 0.995 | 0.094 |
mutually_exclusive (P07737)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PFN2 | SESN1 | 0.994 | 0.086 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PFN1 | NAA80 | 0.967 | 0.108192771084 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only |
| NKX2-5 | PFN2 | 0.941 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NAA80 | SESN1 | 0.214 | 0.124 | bioplex3_WMM WMM_only | |
| NKX2-5 | NAA80 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| NKX2-5 | SESN1 | 0.146 | bioplex3_WMM WMM_only | ||
| PFN1 | PFN2 | 0.015 | 0.222 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM |
Related Complexes