hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14699.1
Complex Portal: CPX-20004
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CEACAM8 | Carcinoembryonic antigen-related cell adhesion molecule 8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b) | 5 | UniProt NCBI |
| RHBDD1 | Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) | 5 | UniProt NCBI |
| C8G | Complement component C8 gamma chain | 5 | UniProt NCBI |
| SERPINI1 | Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1) | 5 | UniProt NCBI |
| CEACAM6 | Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c) | 5 | UniProt NCBI |
| CHI3L1 | Chitinase-3-like protein 1 (39 kDa synovial protein) (Cartilage glycoprotein 39) (CGP-39) (GP-39) (hCGP-39) (YKL-40) | 5 | UniProt NCBI |
| ALOX5AP | Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1566977 | 0.00025805759528 | 0.333333333333 | CEACAM6 CEACAM8 | Fibronectin matrix formation |
| REAC:R-HSA-168249 | 0.0338175140237 | 0.666666666667 | C8G CEACAM8 CHI3L1 CEACAM6 | Innate Immune System |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RHBDD1 | CEACAM6 | 0.986 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RHBDD1 | ALOX5AP | 0.951 | 0.086 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RHBDD1 | CHI3L1 | 0.95 | 0.178 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RHBDD1 | C8G | 0.94 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RHBDD1 | CEACAM8 | 0.938 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ALOX5AP | C8G | 0.904 | bioplex3_WMM WMM_only | ||
| CEACAM6 | ALOX5AP | 0.902 | bioplex3_WMM WMM_only | ||
| ALOX5AP | CEACAM8 | 0.902 | bioplex3_WMM WMM_only | ||
| CEACAM6 | C8G | 0.902 | bioplex3_WMM WMM_only | ||
| CEACAM8 | C8G | 0.892 | bioplex3_WMM WMM_only | ||
| CEACAM6 | CHI3L1 | 0.869 | bioplex3_WMM WMM_only | ||
| CEACAM6 | CEACAM8 | 0.845 | bioplex3_WMM WMM_only | ||
| CEACAM8 | SERPINI1 | 0.843 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ALOX5AP | CHI3L1 | 0.418 | 0.086 | bioplex3_WMM WMM_only | |
| CHI3L1 | C8G | 0.401 | bioplex3_WMM WMM_only | ||
| CHI3L1 | CEACAM8 | 0.401 | bioplex3_WMM WMM_only |
Related Complexes