hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14710.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EEF2KMT | Protein-lysine N-methyltransferase EEF2KMT (EC 2.1.1.-) (eEF2-lysine methyltransferase) (eEF2-KMT) | 5 | UniProt NCBI |
| XDH | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] | 5 | UniProt NCBI |
| LPL | Lipoprotein lipase (LPL) (EC 3.1.1.34) (Phospholipase A1) (EC 3.1.1.32) | 5 | UniProt NCBI |
| GALC | Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) | 5 | UniProt NCBI |
| MTRFR | Mitochondrial translation release factor in rescue | 5 | UniProt NCBI |
| A6NL58 | None | UniProt NCBI | |
| A6ND20 | None | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010830 | 0.0316815705386 | 0.4 | GALC MTRFR | Impaired tactile sensation |
| CORUM:6066 | 0.0498708842806 | 0.2 | XDH | Xanthine oxidase |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EEF2KMT | LPL | 0.998 | 0.098 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MTRFR | XDH | 0.998 | 0.06 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MTRFR | LPL | 0.997 | 0.104 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| EEF2KMT | GALC | 0.978 | 0.048 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| EEF2KMT | A6NL58 | 0.944 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| EEF2KMT | A6ND20 | 0.922 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| A6ND20 | A6NL58 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LPL | A6ND20 | 0.902 | bioplex3_WMM WMM_only | ||
| LPL | A6NL58 | 0.902 | bioplex3_WMM WMM_only | ||
| XDH | LPL | 0.821 | 0.12 | bioplex3_WMM WMM_only boldt_WMM | |
| GALC | A6ND20 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GALC | A6NL58 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GALC | LPL | 0.042 | 0.082 | bioplex3_WMM WMM_only |
Related Complexes