hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14714.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DYNC2LI1 | Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) | 5 | UniProt NCBI |
| CLMP | CXADR-like membrane protein (Adipocyte adhesion molecule) (Coxsackie- and adenovirus receptor-like membrane protein) (CAR-like membrane protein) | 5 | UniProt NCBI |
| UTP20 | Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6) | 5 | UniProt NCBI |
| DYNC2H1 | Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6236 | 0.000338026191524 | 0.5 | DYNC2LI1 DYNC2H1 | Dynein-2 complex, cytoplasmic |
| WP:WP4532 | 0.000894348084449 | 0.5 | DYNC2LI1 DYNC2H1 | Intraflagellar transport proteins binding to dynein |
| KEGG:04962 | 0.00194963326435 | 0.5 | DYNC2LI1 DYNC2H1 | Vasopressin-regulated water reabsorption |
| WP:WP5085 | 0.00198508114189 | 0.5 | DYNC2LI1 DYNC2H1 | Vasopressin regulated water reabsorption |
| HP:0000888 | 0.00350734148159 | 0.5 | DYNC2LI1 DYNC2H1 | Horizontal ribs |
| WP:WP4906 | 0.00405547408869 | 0.5 | DYNC2LI1 DYNC2H1 | 3q29 copy number variation syndrome |
| WP:WP5234 | 0.00722934152515 | 0.5 | DYNC2LI1 DYNC2H1 | Bardet Biedl syndrome |
| HP:0005483 | 0.00771122114953 | 0.5 | DYNC2LI1 DYNC2H1 | Abnormal epiglottis morphology |
| WP:WP4536 | 0.0120322522645 | 0.5 | DYNC2LI1 DYNC2H1 | Genes related to primary cilium development based on CRISPR |
| REAC:R-HSA-5620924 | 0.0130136556072 | 0.5 | DYNC2LI1 DYNC2H1 | Intraflagellar transport |
| HP:0000090 | 0.018706736024 | 0.5 | DYNC2LI1 DYNC2H1 | Nephronophthisis |
| HP:0010306 | 0.0259951101914 | 0.5 | DYNC2LI1 DYNC2H1 | Short thorax |
| WP:WP4803 | 0.030443565418 | 0.5 | DYNC2LI1 DYNC2H1 | Ciliopathies |
| KEGG:04814 | 0.0322340970049 | 0.5 | DYNC2LI1 DYNC2H1 | Motor proteins |
| HPA:0060873 | 0.0333763741956 | 0.5 | DYNC2LI1 DYNC2H1 | bronchus; ciliated cells (ciliary rootlets)[High] |
| HP:0000795 | 0.0471163420483 | 0.75 | DYNC2H1 DYNC2LI1 CLMP | Abnormality of the urethra |
| HP:0100957 | 0.0476300363671 | 0.5 | DYNC2LI1 DYNC2H1 | Abnormal renal medulla morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DYNC2LI1 | DYNC2H1 | 0.998 | 0.1 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| DYNC2LI1 | UTP20 | 0.988 | 0.05 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| UTP20 | CLMP | 0.919 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| DYNC2H1 | UTP20 | 0.043 | 0.022 | bioplex3_WMM fraction |
Related Complexes