hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14729.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRRT4 | Proline-rich transmembrane protein 4 | 3 | UniProt NCBI |
| PITPNM1 | Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) | 5 | UniProt NCBI |
| RASSF1 | Ras association domain-containing protein 1 | 5 | UniProt NCBI |
| PITPNM2 | Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) | 5 | UniProt NCBI |
| OSBP2 | Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4) | 5 | UniProt NCBI |
| SLC22A15 | Solute carrier family 22 member 15 (Fly-like putative transporter 1) (Flipt 1) | 5 | UniProt NCBI |
| OSBPL10 | Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10) | 5 | UniProt NCBI |
| PITPNM3 | Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1) | 5 | UniProt NCBI |
| OSBPL2 | Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2) | 5 | UniProt NCBI |
| RASSF3 | Ras association domain-containing protein 3 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0008526 | 3.86287613381e-07 | 0.4 | PITPNM2 OSBPL2 PITPNM1 PITPNM3 | phosphatidylinositol transfer activity |
| REAC:R-HSA-1483226 | 5.56817285598e-07 | 0.3 | PITPNM2 PITPNM1 PITPNM3 | Synthesis of PI |
| GO:0005548 | 1.90997383037e-06 | 0.5 | PITPNM2 OSBPL2 PITPNM3 PITPNM1 OSBPL10 | phospholipid transporter activity |
| GO:0005319 | 2.12967255275e-06 | 0.6 | PITPNM2 OSBPL2 OSBPL10 OSBP2 PITPNM1 PITPNM3 | lipid transporter activity |
| GO:0120014 | 2.66313661765e-05 | 0.4 | PITPNM2 OSBPL2 PITPNM1 PITPNM3 | phospholipid transfer activity |
| REAC:R-HSA-1483206 | 0.000123429301917 | 0.4 | PITPNM2 PITPNM3 PITPNM1 OSBPL10 | Glycerophospholipid biosynthesis |
| GO:0120013 | 0.000449289899845 | 0.4 | PITPNM2 OSBPL2 PITPNM1 PITPNM3 | lipid transfer activity |
| REAC:R-HSA-1483257 | 0.000974345267861 | 0.4 | PITPNM2 PITPNM3 PITPNM1 OSBPL10 | Phospholipid metabolism |
| GO:0005215 | 0.00598661173167 | 0.7 | PITPNM2 OSBPL2 OSBPL10 OSBP2 SLC22A15 PITPNM3 PITPNM1 | transporter activity |
| REAC:R-HSA-556833 | 0.00647119386342 | 0.5 | PITPNM2 OSBPL2 PITPNM3 PITPNM1 OSBPL10 | Metabolism of lipids |
| GO:0015248 | 0.0297425210859 | 0.3 | OSBPL10 OSBP2 OSBPL2 | sterol transporter activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLC22A15 | OSBPL2 | 0.904 | bioplex3_WMM WMM_only | |
| SLC22A15 | RASSF3 | 0.904 | bioplex3_WMM WMM_only | |
| PRRT4 | RASSF1 | 0.904 | bioplex3_WMM WMM_only | |
| PRRT4 | RASSF3 | 0.902 | bioplex3_WMM WMM_only | |
| PITPNM1 | PRRT4 | 0.902 | bioplex3_WMM WMM_only | |
| SLC22A15 | PITPNM1 | 0.902 | bioplex3_WMM WMM_only | |
| PITPNM2 | RASSF3 | 0.902 | 0.072 | bioplex3_WMM WMM_only |
| SLC22A15 | PITPNM2 | 0.902 | bioplex3_WMM WMM_only | |
| PRRT4 | PITPNM2 | 0.902 | bioplex3_WMM WMM_only | |
| SLC22A15 | PRRT4 | 0.902 | bioplex3_WMM WMM_only | |
| PRRT4 | OSBPL2 | 0.902 | bioplex3_WMM WMM_only | |
| OSBP2 | PRRT4 | 0.902 | bioplex3_WMM WMM_only | |
| PITPNM1 | RASSF3 | 0.902 | 0.088 | bioplex3_WMM WMM_only |
| PITPNM3 | PRRT4 | 0.902 | bioplex3_WMM WMM_only | |
| OSBP2 | PITPNM2 | 0.897 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM1 | OSBP2 | 0.897 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC22A15 | RASSF1 | 0.892 | bioplex3_WMM WMM_only | |
| PITPNM1 | PITPNM2 | 0.881 | 0.086 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM2 | OSBPL10 | 0.88 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM1 | OSBPL10 | 0.88 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only |
| OSBPL2 | RASSF3 | 0.869 | 0.056 | bioplex3_WMM WMM_only |
| OSBP2 | OSBPL10 | 0.849 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM3 | PITPNM2 | 0.843 | bioplex_WMM bioplex3_WMM WMM_only | |
| PITPNM1 | PITPNM3 | 0.843 | bioplex_WMM bioplex3_WMM WMM_only | |
| PITPNM1 | RASSF1 | 0.828 | 0.068 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| RASSF3 | RASSF1 | 0.81 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM2 | OSBPL2 | 0.797 | 0.086 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM1 | OSBPL2 | 0.797 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM3 | OSBPL2 | 0.793 | bioplex_WMM bioplex3_WMM WMM_only | |
| PITPNM3 | RASSF1 | 0.793 | bioplex_WMM bioplex3_WMM WMM_only | |
| PITPNM2 | RASSF1 | 0.781 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM3 | OSBP2 | 0.778 | bioplex_WMM bioplex3_WMM WMM_only | |
| OSBPL2 | RASSF1 | 0.739 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM3 | RASSF3 | 0.722 | bioplex3_WMM WMM_only | |
| SLC22A15 | OSBP2 | 0.722 | bioplex3_WMM WMM_only | |
| SLC22A15 | PITPNM3 | 0.717 | bioplex3_WMM WMM_only | |
| PRRT4 | OSBPL10 | 0.676 | bioplex3_WMM WMM_only | |
| OSBP2 | RASSF3 | 0.647 | 0.066 | bioplex3_WMM WMM_only |
| OSBPL2 | OSBPL10 | 0.641 | 0.02 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC22A15 | OSBPL10 | 0.633 | bioplex3_WMM WMM_only | |
| OSBPL10 | RASSF1 | 0.623 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only |
| PITPNM3 | OSBPL10 | 0.617 | bioplex_WMM bioplex3_WMM WMM_only | |
| OSBP2 | RASSF1 | 0.594 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| OSBP2 | OSBPL2 | 0.594 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
| RASSF3 | OSBPL10 | 0.401 | 0.032 | bioplex3_WMM WMM_only |
Related Complexes