hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14732.1
Complex Portal: CPX-11720
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FMO5 | Flavin-containing monooxygenase 5 (FMO 5) (Baeyer-Villiger monooxygenase 1) (hBVMO1) (EC 1.14.13.-) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (NADPH oxidase) (EC 1.6.3.1) | 5 | UniProt NCBI |
| OGA | Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT) | 5 | UniProt NCBI |
| RIDA | 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog) | 5 | UniProt NCBI |
| FMO1 | Flavin-containing monooxygenase 1 (EC 1.14.13.148) (EC 1.14.13.8) (Dimethylaniline monooxygenase [N-oxide-forming] 1) (Dimethylaniline oxidase 1) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Trimethylamine monooxygenase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP688 | 2.55382210955e-06 | 0.5 | FMO5 FMO1 | Catalytic cycle of mammalian flavin containing monooxygenases FMOs |
| KEGG:00430 | 0.000112787442643 | 0.5 | FMO5 FMO1 | Taurine and hypotaurine metabolism |
| GO:0004499 | 0.0028092043205 | 0.5 | FMO5 FMO1 | N,N-dimethylaniline monooxygenase activity |
| KEGG:00982 | 0.00357225272753 | 0.5 | FMO5 FMO1 | Drug metabolism - cytochrome P450 |
| GO:0070995 | 0.00842684400117 | 0.5 | FMO5 FMO1 | NADPH oxidation |
| WP:WP702 | 0.0228199530946 | 0.5 | FMO5 FMO1 | Metapathway biotransformation Phase I and II |
| REAC:R-HSA-217271 | 0.0499436884912 | 0.25 | FMO1 | FMO oxidises nucleophiles |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FMO5 | FMO1 | 0.981 | 0.03 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FMO5 | OGA | 0.915 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RIDA | OGA | 0.884 | 0.042 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| FMO5 | huMAP3_01007.1 huMAP3_14732.1 |
| OGA | huMAP3_03530.1 huMAP3_05654.1 huMAP3_07128.1 huMAP3_08734.1 huMAP3_09179.1 huMAP3_10405.1 huMAP3_14732.1 |
| RIDA | huMAP3_02037.1 huMAP3_14732.1 |
| FMO1 | huMAP3_01007.1 huMAP3_14732.1 |