hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14741.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RNF114 | E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313) | 5 | UniProt NCBI |
| AQP1 | Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Urine water channel) (Water channel protein for red blood cells and kidney proximal tubule) | 5 | UniProt NCBI |
| PLPP4 | Phospholipid phosphatase 4 (EC 3.1.3.4) (EC 3.6.1.75) (Phosphatidic acid phosphatase type 2 domain-containing protein 1A) | 5 | UniProt NCBI |
| PARP12 | Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) | 5 | UniProt NCBI |
| PARP11 | Protein mono-ADP-ribosyltransferase PARP11 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11) (Poly [ADP-ribose] polymerase 11) (PARP-11) | 5 | UniProt NCBI |
| PARP9 | Protein mono-ADP-ribosyltransferase PARP9 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein) (Poly [ADP-ribose] polymerase 9) (PARP-9) | 5 | UniProt NCBI |
| TIPARP | Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase) | 5 | UniProt NCBI |
| RNF166 | E3 ubiquitin-protein ligase RNF166 (EC 2.3.2.27) (RING finger protein 166) (RING-type E3 ubiquitin transferase RNF166) | 5 | UniProt NCBI |
| DTX3L | E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2) | 5 | UniProt NCBI |
| HECTD2 | Probable E3 ubiquitin-protein ligase HECTD2 (EC 2.3.2.26) (HECT domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECTD2) | 4 | UniProt NCBI |
| BOLL | Protein boule-like | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1990404 | 1.00171038812e-05 | 0.4 | PARP9 PARP12 TIPARP PARP11 | NAD+-protein ADP-ribosyltransferase activity |
| GO:0003950 | 2.13120989366e-05 | 0.4 | PARP9 PARP12 TIPARP PARP11 | NAD+ ADP-ribosyltransferase activity |
| CORUM:7384 | 3.07577115383e-05 | 0.2 | PARP9 DTX3L | DTX3L-PARP9 complex |
| CORUM:7385 | 9.22394575203e-05 | 0.2 | PARP9 DTX3L | DTX3L-PARP9-STAT1 complex |
| GO:0016763 | 0.00081226844944 | 0.4 | PARP9 PARP12 TIPARP PARP11 | pentosyltransferase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RNF166 | RNF114 | 0.998 | 0.03 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HECTD2 | RNF166 | 0.993 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RNF166 | PARP9 | 0.991 | 0.06 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| DTX3L | PARP9 | 0.988 | 0.548 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
| RNF166 | PARP12 | 0.981 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RNF166 | PARP11 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RNF166 | PLPP4 | 0.922 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| RNF166 | BOLL | 0.922 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PARP12 | RNF114 | 0.917 | 0.04 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| HECTD2 | PARP9 | 0.904 | bioplex3_WMM WMM_only | |
| RNF166 | AQP1 | 0.896 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PARP11 | RNF114 | 0.884 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TIPARP | RNF114 | 0.839 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| RNF114 | PLPP4 | 0.799 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| HECTD2 | RNF114 | 0.595 | bioplex_WMM bioplex3_WMM WMM_only | |
| RNF166 | TIPARP | 0.373 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PARP9 | RNF114 | 0.151 | 0.05 | bioplex3_WMM WMM_only |
Related Complexes