hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14793.1
Complex Portal: CPX-18222
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNB1 | Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1) | 5 | UniProt NCBI |
| SYNE1 | Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) | 5 | UniProt NCBI |
| MMP19 | Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7506 | 0.0249718442456 | 0.333333333333 | KCNB1 | Potassium channel complex (KCNB1, KCNE2) |
| CORUM:7507 | 0.0249718442456 | 0.333333333333 | KCNB1 | Potassium channel complex (KCNB1, KCNE1) |
| HP:0012795 | 0.0394523409679 | 1.0 | SYNE1 KCNB1 MMP19 | Abnormal optic disc morphology |
| CORUM:6270 | 0.0499402709677 | 0.333333333333 | SYNE1 | DMTN-SYNE1- complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNB1 | MMP19 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MMP19 | SYNE1 | 0.939 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNB1 | SYNE1 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| KCNB1 | huMAP3_02401.1 huMAP3_14793.1 |
| SYNE1 | huMAP3_05082.1 huMAP3_09493.1 huMAP3_14793.1 |
| MMP19 | huMAP3_02401.1 huMAP3_14793.1 |