hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14801.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
KDM5C	Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C)	5	UniProt NCBI
GTF3C5	General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon)	5	UniProt NCBI
SCML4	Sex comb on midleg-like protein 4	3	UniProt NCBI
GTF3C3	General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)	5	UniProt NCBI
GTF3C1	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)	5	UniProt NCBI
ZNF785	Zinc finger protein 785	5	UniProt NCBI
ZNF688	Zinc finger protein 688	5	UniProt NCBI
GTF3C4	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta)	5	UniProt NCBI
GTF3C6	General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6)	5	UniProt NCBI
ZNF764	Zinc finger protein 764	5	UniProt NCBI
SMARCAD1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)	5	UniProt NCBI
PDZRN3	E3 ubiquitin-protein ligase PDZRN3 (EC 2.3.2.27) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (RING-type E3 ubiquitin transferase PDZRN3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	5	UniProt NCBI
ATG4B	Cysteine protease ATG4B (EC 3.4.22.-) (AUT-like 1 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 1) (Autophagin-1) (Autophagy-related protein 4 homolog B) (HsAPG4B) (hAPG4B)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0000127	6.95001783241e-11	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	transcription factor TFIIIC complex
GO:0042791	6.95001783241e-11	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	5S class rRNA transcription by RNA polymerase III
CORUM:1105	1.05641911521e-10	0.307692307692	GTF3C5 GTF3C4 GTF3C1 GTF3C3	transcription factor IIIC multisubunit complex
CORUM:1101	1.05641911521e-10	0.307692307692	GTF3C5 GTF3C4 GTF3C1 GTF3C3	transcription factor IIIC multisubunit complex
CORUM:1113	1.05641911521e-10	0.307692307692	GTF3C5 GTF3C4 GTF3C1 GTF3C3	5S-DNA-TFIIIA-TFIIIC2 subcomplex
CORUM:1106	3.16769554386e-10	0.307692307692	GTF3C5 GTF3C4 GTF3C1 GTF3C3	TFIIIC containing-TOP1-SUB1 complex
GO:0090576	6.48076439894e-10	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA polymerase III transcription regulator complex
CORUM:1114	7.3876470612e-10	0.307692307692	GTF3C5 GTF3C4 GTF3C1 GTF3C3	5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex
GO:0042797	2.91368265705e-09	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	tRNA transcription by RNA polymerase III
REAC:R-HSA-76066	4.12582875541e-09	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA Polymerase III Transcription Initiation From Type 2 Promoter
REAC:R-HSA-76061	4.12582875541e-09	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA Polymerase III Transcription Initiation From Type 1 Promoter
GO:0009304	5.3393134954e-09	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	tRNA transcription
GO:0000995	9.14893106478e-09	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA polymerase III general transcription initiation factor activity
REAC:R-HSA-76046	1.73889898288e-08	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA Polymerase III Transcription Initiation
REAC:R-HSA-749476	3.58985206677e-08	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA Polymerase III Abortive And Retractive Initiation
REAC:R-HSA-74158	3.58985206677e-08	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	RNA Polymerase III Transcription
GO:0009303	1.36120981936e-06	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	rRNA transcription
GO:0006383	1.94572846871e-05	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	transcription by RNA polymerase III
GO:0140223	1.94572846871e-05	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	general transcription initiation factor activity
REAC:R-HSA-74160	0.000882385919153	0.615384615385	GTF3C5 GTF3C1 ZNF764 ZNF688 GTF3C3 GTF3C4 GTF3C6 ZNF785	Gene expression (Transcription)
GO:0098781	0.00106897234109	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	ncRNA transcription
GO:0006399	0.0150632391579	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	tRNA metabolic process
GO:0016072	0.0262121631082	0.384615384615	GTF3C5 GTF3C6 GTF3C4 GTF3C1 GTF3C3	rRNA metabolic process

Edges

Protein 1	Protein 2	Score	ProteomeHD
GTF3C5	GTF3C3	1.0	0.97
GTF3C1	GTF3C3	1.0	0.866
GTF3C5	GTF3C1	1.0	0.684
GTF3C4	GTF3C5	1.0	0.558
GTF3C4	GTF3C1	0.999	0.538
GTF3C4	GTF3C3	0.999	0.63
GTF3C1	ZNF764	0.998
GTF3C3	ZNF764	0.998
ZNF764	KDM5C	0.995
GTF3C3	KDM5C	0.994
GTF3C6	ZNF785	0.994
GTF3C1	KDM5C	0.99
PDZRN3	ZNF785	0.989
GTF3C4	ZNF764	0.989
SMARCAD1	ZNF785	0.988
GTF3C4	ZNF785	0.986
GTF3C4	ZNF688	0.984
GTF3C5	KDM5C	0.984
ATG4B	KDM5C	0.979
GTF3C1	ZNF785	0.975
ZNF764	SMARCAD1	0.974
GTF3C3	ZNF785	0.961
GTF3C5	ZNF764	0.952
GTF3C4	GTF3C6	0.937	0.108
SCML4	KDM5C	0.92
ZNF764	ATG4B	0.902
ZNF688	GTF3C6	0.902
GTF3C5	ZNF785	0.824
GTF3C3	GTF3C6	0.812	0.198
GTF3C1	GTF3C6	0.776	0.164
GTF3C4	KDM5C	0.775
GTF3C5	SMARCAD1	0.562	0.16
GTF3C3	SMARCAD1	0.549	0.324
ZNF688	GTF3C1	0.467
GTF3C5	GTF3C6	0.444	0.204
ZNF688	ZNF764	0.415
GTF3C1	ATG4B	0.303	0.054
ZNF688	GTF3C3	0.249
SMARCAD1	KDM5C	0.243
ZNF688	GTF3C5	0.201
GTF3C6	PDZRN3	0.187	0.118
GTF3C3	ATG4B	0.168	0.016
GTF3C4	ATG4B	0.167	0.042
SMARCAD1	GTF3C6	0.165	0.114
GTF3C5	ATG4B	0.113	0.026
GTF3C1	SMARCAD1	0.097	0.162
SMARCAD1	PDZRN3	0.085	0.03
ZNF764	GTF3C6	0.043
GTF3C5	PDZRN3	0.036	0.05
GTF3C3	PDZRN3	0.029	0.06
GTF3C4	SMARCAD1	0.023	0.204
PDZRN3	KDM5C	0.02
GTF3C4	PDZRN3	0.01	0.04
GTF3C1	PDZRN3	0.004	0.062

Related Complexes

Genename	Complexes
KDM5C	huMAP3_02445.1 huMAP3_05598.1 huMAP3_05651.1 huMAP3_07997.1 huMAP3_08803.1 huMAP3_09735.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_12568.1 huMAP3_14801.1
GTF3C5	huMAP3_00436.1 huMAP3_01637.1 huMAP3_08803.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_14801.1
SCML4	huMAP3_01986.1 huMAP3_04022.1 huMAP3_14115.1 huMAP3_14801.1 huMAP3_14816.1 huMAP3_14927.1
GTF3C3	huMAP3_00436.1 huMAP3_01637.1 huMAP3_08803.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_14801.1
GTF3C1	huMAP3_00436.1 huMAP3_01637.1 huMAP3_08803.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_14801.1
ZNF785	huMAP3_01526.1 huMAP3_02527.1 huMAP3_05598.1 huMAP3_06596.1 huMAP3_07981.1 huMAP3_08274.1 huMAP3_10875.1 huMAP3_14801.1
ZNF688	huMAP3_00337.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_12845.1 huMAP3_13267.1 huMAP3_13532.1 huMAP3_13752.1 huMAP3_14801.1
GTF3C4	huMAP3_00337.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_13752.1 huMAP3_14801.1
GTF3C6	huMAP3_00787.1 huMAP3_02065.1 huMAP3_02527.1 huMAP3_06596.1 huMAP3_07981.1 huMAP3_08274.1 huMAP3_13752.1 huMAP3_14784.1 huMAP3_14801.1
ZNF764	huMAP3_00495.1 huMAP3_02445.1 huMAP3_05598.1 huMAP3_07997.1 huMAP3_08803.1 huMAP3_09735.1 huMAP3_09865.1 huMAP3_10249.1 huMAP3_10875.1 huMAP3_11486.1 huMAP3_13566.1 huMAP3_14801.1
SMARCAD1	huMAP3_00739.1 huMAP3_02749.1 huMAP3_05598.1 huMAP3_07981.1 huMAP3_10393.1 huMAP3_10875.1 huMAP3_11486.1 huMAP3_12648.1 huMAP3_13566.1 huMAP3_14314.1 huMAP3_14801.1
PDZRN3	huMAP3_01526.1 huMAP3_02527.1 huMAP3_05162.1 huMAP3_06596.1 huMAP3_07981.1 huMAP3_08274.1 huMAP3_10606.1 huMAP3_10875.1 huMAP3_11926.1 huMAP3_13645.1 huMAP3_14801.1
ATG4B	huMAP3_01046.1 huMAP3_01453.1 huMAP3_05651.1 huMAP3_11993.1 huMAP3_12186.1 huMAP3_12465.1 huMAP3_14012.1 huMAP3_14801.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_14801.1