hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14821.1
Complex Portal: CPX-22178
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TBKBP1 | TANK-binding kinase 1-binding protein 1 (TBK1-binding protein 1) | 5 | UniProt NCBI |
| ANGPT4 | Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3) | 5 | UniProt NCBI |
| ANGPT1 | Angiopoietin-1 (ANG-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-210993 | 0.000715513386354 | 0.666666666667 | ANGPT4 ANGPT1 | Tie2 Signaling |
| WP:WP3303 | 0.00220609191376 | 0.666666666667 | ANGPT4 ANGPT1 | RAC1 PAK1 p38 MMP2 pathway |
| KEGG:04066 | 0.00368672413844 | 0.666666666667 | ANGPT4 ANGPT1 | HIF-1 signaling pathway |
| KEGG:04015 | 0.010376143546 | 0.666666666667 | ANGPT4 ANGPT1 | Rap1 signaling pathway |
| KEGG:04014 | 0.0127453972967 | 0.666666666667 | ANGPT4 ANGPT1 | Ras signaling pathway |
| KEGG:04010 | 0.0221986078054 | 0.666666666667 | ANGPT4 ANGPT1 | MAPK signaling pathway |
| KEGG:04151 | 0.0307080825491 | 0.666666666667 | ANGPT4 ANGPT1 | PI3K-Akt signaling pathway |
| WP:WP3932 | 0.0343043102958 | 0.666666666667 | ANGPT4 ANGPT1 | Focal adhesion PI3K Akt mTOR signaling pathway |
| REAC:R-HSA-202733 | 0.0349616412881 | 0.666666666667 | ANGPT4 ANGPT1 | Cell surface interactions at the vascular wall |
| WP:WP4172 | 0.0409328508823 | 0.666666666667 | ANGPT4 ANGPT1 | PI3K Akt signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ANGPT4 | ANGPT1 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ANGPT4 | TBKBP1 | 0.905 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ANGPT1 | TBKBP1 | 0.274 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TBKBP1 | huMAP3_11248.1 huMAP3_11496.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_14821.1 huMAP3_15146.1 huMAP3_15257.1 |
| ANGPT4 | huMAP3_04357.1 huMAP3_11248.1 huMAP3_14821.1 |
| ANGPT1 | huMAP3_04357.1 huMAP3_11248.1 huMAP3_14821.1 |