hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14836.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HLA-DQA1 | HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain) (DC-alpha) (HLA-DCA) (MHC class II DQA1) | 5 | UniProt NCBI |
| HLA-DQA2 | HLA class II histocompatibility antigen, DQ alpha 2 chain (DX alpha chain) (HLA class II histocompatibility antigen, DQ(6) alpha chain) (HLA-DQA1) (MHC class II DQA2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-202430 | 0.000133283416666 | 1.0 | HLA-DQA1 HLA-DQA2 | Translocation of ZAP-70 to Immunological synapse |
| REAC:R-HSA-202427 | 0.00023239159829 | 1.0 | HLA-DQA1 HLA-DQA2 | Phosphorylation of CD3 and TCR zeta chains |
| REAC:R-HSA-389948 | 0.000261440548076 | 1.0 | HLA-DQA1 HLA-DQA2 | PD-1 signaling |
| REAC:R-HSA-202433 | 0.000471618243588 | 1.0 | HLA-DQA1 HLA-DQA2 | Generation of second messenger molecules |
| REAC:R-HSA-388841 | 0.0027271837564 | 1.0 | HLA-DQA1 HLA-DQA2 | Costimulation by the CD28 family |
| REAC:R-HSA-877300 | 0.00486997099357 | 1.0 | HLA-DQA1 HLA-DQA2 | Interferon gamma signaling |
| REAC:R-HSA-202424 | 0.00669151102134 | 1.0 | HLA-DQA1 HLA-DQA2 | Downstream TCR signaling |
| GO:0032395 | 0.00702301080125 | 1.0 | HLA-DQA1 HLA-DQA2 | MHC class II receptor activity |
| REAC:R-HSA-202403 | 0.0095092591506 | 1.0 | HLA-DQA1 HLA-DQA2 | TCR signaling |
| REAC:R-HSA-2132295 | 0.0115956572499 | 1.0 | HLA-DQA1 HLA-DQA2 | MHC class II antigen presentation |
| GO:0002503 | 0.0210690324038 | 1.0 | HLA-DQA1 HLA-DQA2 | peptide antigen assembly with MHC class II protein complex |
| GO:0002399 | 0.0210690324038 | 1.0 | HLA-DQA1 HLA-DQA2 | MHC class II protein complex assembly |
| GO:0042613 | 0.0257510396046 | 1.0 | HLA-DQA1 HLA-DQA2 | MHC class II protein complex |
| REAC:R-HSA-913531 | 0.0260158976762 | 1.0 | HLA-DQA1 HLA-DQA2 | Interferon Signaling |
| GO:0002501 | 0.0365196561665 | 1.0 | HLA-DQA1 HLA-DQA2 | peptide antigen assembly with MHC protein complex |
| GO:0002396 | 0.0365196561665 | 1.0 | HLA-DQA1 HLA-DQA2 | MHC protein complex assembly |
| KEGG:05310 | 0.0403663802771 | 0.5 | HLA-DQA2 | Asthma |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HLA-DQA2 | HLA-DQA1 | 0.998 | 0.352 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| HLA-DQA1 | huMAP3_03754.1 huMAP3_07234.1 huMAP3_08674.1 huMAP3_14836.1 |
| HLA-DQA2 | huMAP3_03754.1 huMAP3_07234.1 huMAP3_08674.1 huMAP3_14836.1 |