hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14845.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SHC1 | SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) | 5 | UniProt   NCBI |
ALK | ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246) | 5 | UniProt   NCBI |
OXT | Oxytocin-neurophysin 1 (OT-NPI) [Cleaved into: Oxytocin (Ocytocin); Neurophysin 1] | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-9717264 | 0.0249718442457 | 0.5 | ALK | ASP-3026-resistant ALK mutants |
  REAC:R-HSA-9700649 | 0.0249718442457 | 0.5 | ALK | Drug resistance of ALK mutants |
  REAC:R-HSA-9717301 | 0.0249718442457 | 0.5 | ALK | NVP-TAE684-resistant ALK mutants |
  REAC:R-HSA-9717316 | 0.0249718442457 | 0.5 | ALK | alectinib-resistant ALK mutants |
  REAC:R-HSA-9717319 | 0.0249718442457 | 0.5 | ALK | brigatinib-resistant ALK mutants |
  REAC:R-HSA-9717323 | 0.0249718442457 | 0.5 | ALK | ceritinib-resistant ALK mutants |
  REAC:R-HSA-9717326 | 0.0249718442457 | 0.5 | ALK | crizotinib-resistant ALK mutants |
  REAC:R-HSA-9717329 | 0.0249718442457 | 0.5 | ALK | lorlatinib-resistant ALK mutants |
  HPA:0260133 | 0.0351752340474 | 0.5 | OXT | hypothalamus; neuronal cells[High] |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 OXT |  SHC1 | 0.986 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 SHC1 |  ALK | 0.827 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes