hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14846.1

Complex Portal: CPX-24023

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
SSBP1	Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB) (PWP1-interacting protein 17)	5	UniProt NCBI
XPC	DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)	5	UniProt NCBI
HLTF	Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)	5	UniProt NCBI
CLEC1B	C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2)	5	UniProt NCBI
RPA3	Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)	5	UniProt NCBI
APLF	Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)	5	UniProt NCBI
PNKP	Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]	5	UniProt NCBI
RPA4	Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)	5	UniProt NCBI
SSRP1	FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)	5	UniProt NCBI
RPA2	Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)	5	UniProt NCBI
WRN	Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]	5	UniProt NCBI
RNF146	E3 ubiquitin-protein ligase RNF146 (EC 2.3.2.27) (Dactylidin) (Iduna) (RING finger protein 146) (RING-type E3 ubiquitin transferase RNF146)	5	UniProt NCBI
RPA1	Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]	5	UniProt NCBI
TDP1	Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)	5	UniProt NCBI
PARP1	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) [Cleaved into: Poly [ADP-ribose] polymerase 1, processed C-terminus (Poly [ADP-ribose] polymerase 1, 89-kDa form); Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) (Poly [ADP-ribose] polymerase 1, 24-kDa form) (Poly [ADP-ribose] polymerase 1, 28-kDa form)]	5	UniProt NCBI
CHD1L	Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) (Amplified in liver cancer protein 1)	5	UniProt NCBI
CETN2	Centrin-2 (Caltractin isoform 1)	5	UniProt NCBI
XRCC5	X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))	5	UniProt NCBI
PARP2	Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-)	5	UniProt NCBI
MACROD1	ADP-ribose glycohydrolase MACROD1 (MACRO domain-containing protein 1) (O-acetyl-ADP-ribose deacetylase MACROD1) (EC 3.1.1.106) (Protein LRP16) ([Protein ADP-ribosylaspartate] hydrolase MACROD1) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD1) (EC 3.2.2.-)	5	UniProt NCBI
XRCC6	X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)	5	UniProt NCBI
RPAIN	RPA-interacting protein (hRIP)	5	UniProt NCBI
POLB	DNA polymerase beta (EC 2.7.7.7) (5'-deoxyribose-phosphate lyase) (5'-dRP lyase) (EC 4.2.99.-) (AP lyase) (EC 4.2.99.18)	5	UniProt NCBI
XRCC1	DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)	5	UniProt NCBI
XPA	DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)	5	UniProt NCBI
PRIMPOL	DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111)	5	UniProt NCBI
LIG3	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0006281	2.21063478512e-16	0.739130434783	PNKP XPA PRIMPOL CHD1L CETN2 WRN PARP1 XPC LIG3 RPA3 HLTF PARP2 RPA4 RPA1 POLB APLF TDP1	DNA repair
WP:WP4946	5.62317763157e-16	0.478260869565	PNKP CETN2 WRN XPC RPA3 POLB PARP2 RPA1 LIG3 PARP1 XPA	DNA repair pathways full network
GO:0006974	3.02062165199e-15	0.782608695652	PNKP XPA PRIMPOL CHD1L CETN2 WRN PARP1 XPC LIG3 RPA3 HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	DNA damage response
GO:0006259	9.2129603244e-15	0.782608695652	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 POLB APLF TDP1	DNA metabolic process
REAC:R-HSA-73894	3.52768534362e-14	0.565217391304	PNKP CETN2 WRN XPA XPC LIG3 RPA3 CHD1L TDP1 RPA1 POLB PARP1 PARP2	DNA Repair
REAC:R-HSA-5696395	3.51214163428e-13	0.347826086957	CETN2 RPA1 XPC RPA3 CHD1L PARP2 PARP1 XPA	Formation of Incision Complex in GG-NER
REAC:R-HSA-5696399	9.71865018567e-13	0.391304347826	CETN2 RPA1 XPC RPA3 CHD1L PARP2 LIG3 PARP1 XPA	Global Genome Nucleotide Excision Repair (GG-NER)
REAC:R-HSA-5696398	1.1317044235e-11	0.391304347826	CETN2 RPA1 XPC RPA3 CHD1L PARP2 LIG3 PARP1 XPA	Nucleotide Excision Repair
WP:WP5114	1.51036043751e-11	0.347826086957	CETN2 RPA1 XPC RPA3 CHD1L XPA LIG3 PARP1	Nucleotide excision repair in xeroderma pigmentosum
REAC:R-HSA-73933	1.83459378726e-11	0.304347826087	PNKP RPA1 RPA3 LIG3 POLB PARP2 PARP1	Resolution of Abasic Sites (AP sites)
GO:0006284	3.55351324569e-11	0.347826086957	PNKP RPA1 RPA3 LIG3 POLB XPA WRN PARP1	base-excision repair
GO:0033554	1.03742443965e-10	0.782608695652	PNKP XPA PRIMPOL CHD1L CETN2 WRN PARP1 XPC LIG3 RPA3 HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	cellular response to stress
GO:0003684	5.54928479526e-10	0.347826086957	PNKP WRN XPC RPA3 PARP2 RPA1 PARP1 XPA	damaged DNA binding
KEGG:03410	2.70099149654e-09	0.260869565217	PNKP PARP1 POLB PARP2 LIG3 TDP1	Base excision repair
GO:0006302	3.87962074861e-09	0.478260869565	PNKP PARP2 WRN RPA3 PARP1 POLB RPA4 RPA1 LIG3 APLF TDP1	double-strand break repair
REAC:R-HSA-73884	5.73397588662e-09	0.304347826087	PNKP RPA1 RPA3 LIG3 POLB PARP2 PARP1	Base Excision Repair
REAC:R-HSA-5696400	1.04568773938e-08	0.260869565217	RPA1 RPA3 CHD1L PARP2 PARP1 XPA	Dual Incision in GG-NER
KEGG:03420	1.76654433824e-08	0.260869565217	CETN2 RPA1 XPC RPA3 RPA4 XPA	Nucleotide excision repair
GO:0006260	1.86380833392e-08	0.434782608696	PNKP PRIMPOL SSBP1 WRN RPA3 LIG3 POLB RPA4 RPA1 PARP1	DNA replication
GO:0006261	2.03852217629e-08	0.391304347826	PNKP PRIMPOL SSBP1 WRN LIG3 POLB RPA4 RPA1 PARP1	DNA-templated DNA replication
GO:0090734	9.57341960823e-08	0.347826086957	PNKP RPA1 RPA3 APLF CHD1L RPA4 PARP1 PARP2	site of DNA damage
REAC:R-HSA-110373	1.0174423399e-07	0.217391304348	RPA1 PARP2 POLB RPA3 PARP1	Resolution of AP sites via the multiple-nucleotide patch replacement pathway
WP:WP4752	1.05470237948e-07	0.217391304348	PNKP POLB PARP1 LIG3 PARP2	Base excision repair
CORUM:5243	1.07739615662e-07	0.130434782609	PNKP TDP1 LIG3	XRCC1-LIG3-PNK-TDP1 complex
CORUM:362	1.07739615662e-07	0.130434782609	PNKP LIG3 POLB	DNA ligase III-XRCC1-PNK-DNA-pol III multiprotein complex
WP:WP4016	2.06625093263e-07	0.260869565217	WRN POLB XPA RPA1 PARP1 TDP1	DNA IR damage and cellular response via ATR
GO:0005657	2.86036646421e-07	0.304347826087	PRIMPOL WRN RPA3 XPA RPA1 PARP1 RPA4	replication fork
GO:0006950	4.83937124012e-07	0.826086956522	PNKP MACROD1 PRIMPOL CHD1L CETN2 WRN PARP1 XPA RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 CLEC1B POLB APLF TDP1	response to stress
WP:WP4753	7.02970284826e-07	0.217391304348	CETN2 RPA1 XPA XPC RPA3	Nucleotide excision repair
REAC:R-HSA-5693532	1.03297399911e-06	0.304347826087	WRN RPA3 LIG3 PARP2 RPA1 PARP1 TDP1	DNA Double-Strand Break Repair
GO:0006289	1.07196602592e-06	0.304347826087	CETN2 PNKP RPA1 XPC RPA3 RPA4 XPA	nucleotide-excision repair
KEGG:03430	2.49112561543e-06	0.173913043478	RPA1 RPA4 SSBP1 RPA3	Mismatch repair
CORUM:1004	8.99452984903e-06	0.130434782609	RPA1 RPA3 PARP1	RC complex during S-phase of cell cycle
REAC:R-HSA-5693538	1.21131215953e-05	0.260869565217	WRN RPA3 LIG3 PARP2 RPA1 PARP1	Homology Directed Repair
CORUM:1005	1.28361389281e-05	0.130434782609	RPA1 RPA3 PARP1	RC complex during G2/M-phase of cell cycle
GO:0070013	1.6290692267e-05	0.95652173913	WRN RPA3 SSRP1 CETN2 POLB RNF146 HLTF PARP2 RPAIN APLF RPA4 PNKP XPC CHD1L TDP1 SSBP1 PRIMPOL LIG3 XPA RPA1 MACROD1 PARP1	intracellular organelle lumen
GO:0031974	1.6290692267e-05	0.95652173913	WRN RPA3 SSRP1 CETN2 POLB RNF146 HLTF PARP2 RPAIN APLF RPA4 PNKP XPC CHD1L TDP1 SSBP1 PRIMPOL LIG3 XPA RPA1 MACROD1 PARP1	membrane-enclosed lumen
GO:0043233	1.6290692267e-05	0.95652173913	WRN RPA3 SSRP1 CETN2 POLB RNF146 HLTF PARP2 RPAIN APLF RPA4 PNKP XPC CHD1L TDP1 SSBP1 PRIMPOL LIG3 XPA RPA1 MACROD1 PARP1	organelle lumen
KEGG:03030	1.63486074628e-05	0.173913043478	RPA1 RPA4 SSBP1 RPA3	DNA replication
GO:0140097	1.6549829348e-05	0.347826086957	CHD1L WRN POLB LIG3 HLTF TDP1 PRIMPOL APLF	catalytic activity, acting on DNA
REAC:R-HSA-3108214	2.37810580949e-05	0.217391304348	CETN2 WRN PARP1 XPC RPA1	SUMOylation of DNA damage response and repair proteins
KEGG:03440	2.5259126325e-05	0.173913043478	RPA1 RPA4 SSBP1 RPA3	Homologous recombination
GO:0005654	2.83592923666e-05	0.869565217391	PNKP XPA RPAIN CHD1L CETN2 WRN PARP1 XPC LIG3 RPA3 SSRP1 HLTF PARP2 RNF146 RPA4 RPA1 MACROD1 POLB APLF TDP1	nucleoplasm
REAC:R-HSA-5649702	3.82811230328e-05	0.130434782609	PNKP LIG3 POLB	APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
REAC:R-HSA-110362	6.11869241326e-05	0.130434782609	POLB PARP1 PARP2	POLB-Dependent Long Patch Base Excision Repair
CORUM:5229	7.49713811273e-05	0.0869565217391	RPA1 RPA3	RPA complex
CORUM:5235	7.49713811273e-05	0.0869565217391	WRN PARP1	WRN-Ku70-Ku80-PARP1 complex
CORUM:7352	7.49713811273e-05	0.0869565217391	PARP1 LIG3	PARP1-LIG3 complex
GO:0035861	7.60953569476e-05	0.260869565217	PNKP RPA3 APLF CHD1L RPA4 PARP1	site of double-strand break
GO:0031981	9.7139886495e-05	0.869565217391	PNKP XPA RPAIN CHD1L CETN2 WRN PARP1 XPC LIG3 RPA3 SSRP1 HLTF PARP2 RNF146 RPA4 RPA1 MACROD1 POLB APLF TDP1	nuclear lumen
REAC:R-HSA-5696394	0.000107100893456	0.173913043478	CETN2 PARP2 XPC PARP1	DNA Damage Recognition in GG-NER
GO:0005662	0.000165040423252	0.173913043478	RPA1 XPA RPA3 RPA4	DNA replication factor A complex
GO:0043596	0.000168457538004	0.217391304348	RPA1 PARP1 XPA RPA3 RPA4	nuclear replication fork
REAC:R-HSA-5685939	0.000179728307106	0.130434782609	LIG3 PARP1 PARP2	HDR through MMEJ (alt-NHEJ)
CORUM:7295	0.00022469866415	0.0869565217391	RPA1 XPA	ERCC1-RPA1-XPA complex
GO:0032042	0.000314421871079	0.173913043478	PRIMPOL LIG3 SSBP1 PARP1	mitochondrial DNA metabolic process
CORUM:1086	0.00044896681224	0.0869565217391	POLB LIG3	DNA repair complex NEIL1-PNK-Pol(beta)-LigIII(alpha)-XRCC1
CORUM:1085	0.00044896681224	0.0869565217391	POLB LIG3	DNA repair complex NEIL2-PNK-Pol(beta)-LigIII(alpha)-XRCC1
GO:0003697	0.000456654731149	0.260869565217	SSBP1 RPA1 RPA3 XPC RPA4 TDP1	single-stranded DNA binding
GO:0005634	0.000460476294842	0.95652173913	WRN RPA3 SSRP1 CETN2 POLB RNF146 HLTF PARP2 RPAIN APLF RPA4 PNKP XPC CHD1L TDP1 SSBP1 PRIMPOL LIG3 XPA RPA1 MACROD1 PARP1	nucleus
HPA:0330222	0.000584987599948	0.739130434783	PNKP XPA SSBP1 CETN2 WRN PARP1 RPA3 LIG3 XPC CHD1L PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	oral mucosa; squamous epithelial cells[>=Medium]
REAC:R-HSA-174437	0.00073614863329	0.130434782609	WRN RPA3 RPA1	Removal of the Flap Intermediate from the C-strand
CORUM:2222	0.000747561230202	0.0869565217391	RPA1 RPA3	BLM complex II
CORUM:2738	0.000747561230202	0.0869565217391	RPA1 RPA3	BLM complex II
REAC:R-HSA-174414	0.00104685961	0.130434782609	WRN RPA3 RPA1	Processive synthesis on the C-strand of the telomere
GO:0009411	0.00115694148803	0.260869565217	WRN XPC XPA PRIMPOL RPAIN PARP1	response to UV
GO:0005694	0.00120593486185	0.565217391304	PNKP XPA WRN PARP1 RPA3 XPC APLF CHD1L RPA4 RPA1 PRIMPOL SSRP1 PARP2	chromosome
REAC:R-HSA-3108232	0.0012854097409	0.217391304348	CETN2 WRN PARP1 XPC RPA1	SUMO E3 ligases SUMOylate target proteins
REAC:R-HSA-5651801	0.00143391828595	0.130434782609	RPA1 RPA3 POLB	PCNA-Dependent Long Patch Base Excision Repair
REAC:R-HSA-2990846	0.00149731418049	0.217391304348	CETN2 WRN PARP1 XPC RPA1	SUMOylation
HPA:0620222	0.00151676629366	0.695652173913	PNKP SSBP1 CHD1L CETN2 WRN XPA RPA3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN LIG3 PARP1 TDP1	vagina; squamous epithelial cells[>=Medium]
GO:0000002	0.00167274433788	0.173913043478	PRIMPOL LIG3 SSBP1 PARP1	mitochondrial genome maintenance
GO:0043601	0.00167274433788	0.173913043478	RPA1 XPA RPA3 RPA4	nuclear replisome
GO:0043504	0.00169879277018	0.130434782609	PRIMPOL PARP1 LIG3	mitochondrial DNA repair
REAC:R-HSA-6781827	0.00188535330492	0.173913043478	RPA1 LIG3 RPA3 XPA	Transcription-Coupled Nucleotide Excision Repair (TC-NER)
GO:0051716	0.00218419298103	0.869565217391	PNKP MACROD1 PRIMPOL CHD1L CETN2 WRN PARP1 XPA RPA3 LIG3 XPC HLTF PARP2 RNF146 RPA4 RPA1 CLEC1B POLB APLF TDP1	cellular response to stimulus
GO:0030894	0.00242482694796	0.173913043478	RPA1 XPA RPA3 RPA4	replisome
REAC:R-HSA-5696397	0.0024695445471	0.130434782609	RPA1 RPA3 LIG3	Gap-filling DNA repair synthesis and ligation in GG-NER
CORUM:248	0.00268092511124	0.0869565217391	RPA1 RPA3	BRAFT complex
GO:0003677	0.00286391226727	0.565217391304	PNKP XPA SSBP1 PARP2 WRN PARP1 RPA3 XPC HLTF RPA4 RPA1 SSRP1 TDP1	DNA binding
HPA:0460672	0.00286658880338	0.652173913043	PNKP XPA SSBP1 CHD1L RPA1 PARP1 RPA3 LIG3 XPC RNF146 RPA4 RPAIN POLB SSRP1 TDP1	skin 1; melanocytes[>=Medium]
GO:0050896	0.00315225595199	0.913043478261	PNKP MACROD1 PRIMPOL RPAIN CHD1L CETN2 WRN PARP1 XPA RPA3 LIG3 XPC HLTF PARP2 RNF146 RPA4 RPA1 CLEC1B POLB APLF TDP1	response to stimulus
REAC:R-HSA-6804756	0.00335935454073	0.173913043478	WRN RPA1 RPA3 SSRP1	Regulation of TP53 Activity through Phosphorylation
GO:0072572	0.00339409783315	0.130434782609	PARP2 APLF RNF146	poly-ADP-D-ribose binding
GO:0160002	0.00339409783315	0.130434782609	CHD1L APLF PARP2	ADP-D-ribose modification-dependent protein binding
GO:0006139	0.00346749513976	0.826086956522	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	nucleobase-containing compound metabolic process
KEGG:03460	0.00368424416283	0.130434782609	RPA1 RPA3 RPA4	Fanconi anemia pathway
CORUM:244	0.00408801752763	0.0869565217391	RPA1 RPA3	BRAFT complex
REAC:R-HSA-110381	0.00457656492477	0.0869565217391	POLB LIG3	Resolution of AP sites via the single-nucleotide replacement pathway
GO:0009314	0.00461841022237	0.304347826087	PNKP WRN XPC XPA PRIMPOL RPAIN PARP1	response to radiation
WP:WP466	0.00470554581227	0.130434782609	RPA1 RPA3 RPA4	DNA replication
HPA:0190222	0.00523093426717	0.739130434783	PNKP SSBP1 CHD1L CETN2 WRN XPA RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB PARP1 TDP1	esophagus; squamous epithelial cells[>=Medium]
GO:0046483	0.00578465270442	0.826086956522	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	heterocycle metabolic process
REAC:R-HSA-68962	0.00581026889635	0.130434782609	RPA1 RPA3 RPA4	Activation of the pre-replicative complex
GO:0006725	0.00610839874469	0.826086956522	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	cellular aromatic compound metabolic process
GO:0090304	0.0062838493694	0.782608695652	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 POLB APLF TDP1	nucleic acid metabolic process
GO:0000724	0.00629320614948	0.260869565217	WRN RPA3 PARP1 RPA4 RPA1 LIG3	double-strand break repair via homologous recombination
REAC:R-HSA-9709570	0.00636601399978	0.130434782609	WRN RPA3 RPA1	Impaired BRCA2 binding to RAD51
REAC:R-HSA-174417	0.00636601399978	0.130434782609	WRN RPA3 RPA1	Telomere C-strand (Lagging Strand) Synthesis
REAC:R-HSA-5685938	0.00695568324258	0.130434782609	WRN RPA3 RPA1	HDR through Single Strand Annealing (SSA)
GO:0000725	0.00729991150006	0.260869565217	WRN RPA3 PARP1 RPA4 RPA1 LIG3	recombinational repair
HPA:0630052	0.00838179133043	0.652173913043	PNKP SSBP1 CETN2 RPA1 XPA RPA3 LIG3 RNF146 CHD1L XPC RPA4 RPAIN POLB PARP1 TDP1	cervix; glandular cells[>=Medium]
HPA:0460671	0.00957837569837	0.739130434783	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	skin 1; melanocytes[>=Low]
REAC:R-HSA-5693616	0.00967264952063	0.130434782609	WRN RPA3 RPA1	Presynaptic phase of homologous DNA pairing and strand exchange
HP:0003621	0.0101378327784	0.304347826087	PNKP SSBP1 RPA1 XPA WRN LIG3 TDP1	Juvenile onset
HPA:0620000	0.0103621335931	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	vagina
HPA:0620221	0.0103621335931	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	vagina; squamous epithelial cells[>=Low]
REAC:R-HSA-9675136	0.010446189328	0.130434782609	WRN RPA3 RPA1	Diseases of DNA Double-Strand Break Repair
REAC:R-HSA-9701190	0.010446189328	0.130434782609	WRN RPA3 RPA1	Defective homologous recombination repair (HRR) due to BRCA2 loss of function
GO:1901360	0.0114813707769	0.826086956522	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	organic cyclic compound metabolic process
HPA:0380512	0.0118527820237	0.608695652174	PNKP CETN2 WRN XPA RPA3 RNF146 XPC CHD1L RPA4 RPA1 RPAIN LIG3 PARP1 TDP1	placenta; decidual cells[>=Medium]
REAC:R-HSA-5693579	0.0121129856716	0.130434782609	WRN RPA3 RPA1	Homologous DNA Pairing and Strand Exchange
HPA:0380511	0.0152509680484	0.695652173913	PNKP CETN2 WRN XPA RPA3 RNF146 LIG3 XPC CHD1L PARP2 RPA4 RPA1 RPAIN POLB PARP1 TDP1	placenta; decidual cells[>=Low]
GO:0009416	0.0160078601911	0.260869565217	WRN XPC XPA PRIMPOL RPAIN PARP1	response to light stimulus
REAC:R-HSA-9675135	0.0193006855498	0.130434782609	WRN RPA3 RPA1	Diseases of DNA repair
HPA:0330221	0.0193024640344	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	oral mucosa; squamous epithelial cells[>=Low]
HPA:0330000	0.0193024640344	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	oral mucosa
GO:0000012	0.0202810995064	0.130434782609	PARP1 APLF TDP1	single strand break repair
REAC:R-HSA-180786	0.0217711970027	0.130434782609	WRN RPA3 RPA1	Extension of Telomeres
HPA:0630051	0.0246071062192	0.739130434783	PNKP SSBP1 CHD1L CETN2 WRN XPA RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB PARP1 TDP1	cervix; glandular cells[>=Low]
GO:0034641	0.0246451741372	0.826086956522	PNKP XPA PRIMPOL SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC HLTF PARP2 RPA4 RPA1 MACROD1 POLB APLF TDP1	cellular nitrogen compound metabolic process
GO:0140640	0.0252259069443	0.347826086957	CHD1L WRN POLB LIG3 HLTF TDP1 PRIMPOL APLF	catalytic activity, acting on a nucleic acid
REAC:R-HSA-5633007	0.0275386892805	0.173913043478	WRN RPA1 RPA3 SSRP1	Regulation of TP53 Activity
GO:0000109	0.0278578876014	0.130434782609	CETN2 XPC XPA	nucleotide-excision repair complex
GO:0006264	0.0278578876014	0.130434782609	PRIMPOL SSBP1 LIG3	mitochondrial DNA replication
HPA:0040000	0.0280707551987	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN RPAIN RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 CLEC1B POLB PARP1 TDP1	bone marrow
HPA:0040081	0.0280707551987	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN RPAIN RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 CLEC1B POLB PARP1 TDP1	bone marrow; hematopoietic cells[>=Low]
HPA:0090191	0.029013888338	0.652173913043	PNKP XPA CHD1L CETN2 WRN PARP1 XPC RPA3 RNF146 RPA4 RPA1 RPAIN LIG3 SSRP1 PARP2	cerebellum; cells in molecular layer[>=Low]
HPA:0301371	0.0324391274778	0.391304347826	PNKP SSBP1 RPA1 XPC LIG3 CHD1L PARP2 PARP1 XPA	lung; alveolar cells type II[>=Low]
HPA:0380513	0.0348495607474	0.347826086957	PNKP RPA1 RPA3 LIG3 CHD1L XPA RPAIN PARP1	placenta; decidual cells[High]
WP:WP2446	0.0400963184579	0.130434782609	HLTF RPA3 RPA1	Retinoblastoma gene in cancer
REAC:R-HSA-6782210	0.0410071526782	0.130434782609	RPA1 RPA3 LIG3	Gap-filling DNA repair synthesis and ligation in TC-NER
HPA:0610833	0.0420474822818	0.434782608696	PNKP POLB RPA1 XPC RPA3 CHD1L RPA4 RPAIN LIG3 XPA	urinary bladder; urothelial cells[High]
REAC:R-HSA-6782135	0.0429797702741	0.130434782609	RPA1 RPA3 XPA	Dual incision in TC-NER
HPA:0340461	0.0430726814647	0.608695652174	PNKP CETN2 RPA1 PARP1 RPA3 RNF146 LIG3 XPC CHD1L RPA4 RPAIN POLB SSRP1 XPA	ovary; ovarian stroma cells[>=Low]
WP:WP3645	0.044731571894	0.0869565217391	PARP1 PARP2	NAD biosynthetic pathways
REAC:R-HSA-5685942	0.0471083437265	0.130434782609	WRN RPA3 RPA1	HDR through Homologous Recombination (HRR)
GO:0006287	0.0481879293545	0.130434782609	PNKP LIG3 POLB	base-excision repair, gap-filling
GO:0006266	0.0481879293545	0.130434782609	PNKP APLF LIG3	DNA ligation
HPA:0190000	0.0487715282554	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	esophagus
HPA:0190221	0.0487715282554	0.782608695652	PNKP XPA SSBP1 CHD1L CETN2 WRN PARP1 RPA3 LIG3 XPC RNF146 PARP2 RPA4 RPA1 RPAIN POLB SSRP1 TDP1	esophagus; squamous epithelial cells[>=Low]
CORUM:365	0.0498014438088	0.0434782608696	LIG3	DNA ligase III-XRCC1 complex
CORUM:363	0.0498014438088	0.0434782608696	LIG3	DNA ligase III-XRCC1 complex
CORUM:212	0.0498014438088	0.0434782608696	LIG3	DNA ligase III-XRCC1 complex
CORUM:4082	0.0498014438088	0.0434782608696	WRN	XRCC6-XRCC5-WRN complex
WP:WP5103	0.0499462656714	0.0869565217391	WRN PARP1	Progeria associated lipodystrophy
REAC:R-HSA-3371511	0.0499578070164	0.0869565217391	RPA1 RPA3	HSF1 activation

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RPA3	RPA2	1.0	0.958	structurally_consistent (dimer)
RPA1	RPA2	1.0	0.802
RPA3	RPA1	1.0	0.658	mutually_exclusive (Q13156)
XRCC6	XRCC5	1.0	0.96	structurally_consistent (dimer)
LIG3	XRCC1	1.0	0.55
POLB	XRCC1	0.999	0.084	mutually_exclusive (P35244)
POLB	PARP2	0.999	0.04
LIG3	POLB	0.999	0.1
RPA1	RPAIN	0.999	0.196
RPA2	RPAIN	0.999	0.208
WRN	XRCC6	0.999	0.32
XPC	CETN2	0.999	0.08	structurally_consistent (dimer)
RNF146	PARP2	0.999	0.088	structurally_consistent (dimer)
RPA1	RPA4	0.998		structurally_consistent (dimer)
XRCC5	APLF	0.998		structurally_consistent (dimer)
LIG3	PNKP	0.998	0.18
XRCC6	APLF	0.998
XRCC6	RPA2	0.997	0.456
APLF	XPC	0.997
APLF	PARP1	0.997
APLF	PARP2	0.997
RPAIN	RPA4	0.997
XPA	RPA3	0.996	0.106
APLF	LIG3	0.996
LIG3	TDP1	0.996	0.0660385964912
XPC	RPA2	0.995	0.14
XRCC6	PARP1	0.995	0.55	structurally_consistent (dimer)
APLF	RPA2	0.995
APLF	RPA1	0.995
RPA3	RPA4	0.995		structurally_consistent (dimer)
XPC	RPA1	0.994	0.218
APLF	HLTF	0.994
PNKP	POLB	0.994	0.108
SSRP1	PARP1	0.994	0.562
XPC	PARP2	0.993	0.032
PNKP	XRCC1	0.993	0.13
XPC	RPA3	0.993	0.156
SSBP1	RPA2	0.993	0.24
APLF	POLB	0.993
HLTF	CHD1L	0.993	0.09
XPC	PARP1	0.992	0.363073394495
SSBP1	RPA4	0.992
LIG3	PARP2	0.991	0.076
MACROD1	PARP1	0.991	0.166	structurally_consistent (dimer)
APLF	XRCC1	0.99
XPC	RPA4	0.99
XRCC5	RPA2	0.99	0.424
RPA3	RPAIN	0.989	0.288
XPA	RPA2	0.989	0.196
LIG3	RPA2	0.989	0.106
SSRP1	APLF	0.989
RNF146	CHD1L	0.988	0.06
XPC	CHD1L	0.988	0.024
POLB	TDP1	0.986	0.13
LIG3	RPA4	0.986		structurally_consistent (dimer)
RPA2	PARP1	0.985	0.424
XPC	RNF146	0.984	0.182	structurally_consistent (dimer)
HLTF	XPC	0.984	0.032
RPA2	PARP2	0.983	0.048
APLF	RPA3	0.983
RPAIN	PARP1	0.983	0.226
LIG3	PARP1	0.982	0.53
LIG3	XPC	0.981	0.164
MACROD1	RPA2	0.978	0.026
HLTF	RPA2	0.977	0.07
XPC	POLB	0.976	0.19
POLB	PARP1	0.974	0.313555555556
RPA1	SSBP1	0.974	0.244
LIG3	HLTF	0.973	0.1
HLTF	RPA1	0.972	0.204166666667
RNF146	PARP1	0.972	0.216
RPA4	PARP1	0.97
XRCC6	PARP2	0.97	0.206
SSRP1	POLB	0.97	0.154
PARP2	CHD1L	0.966	0.054
XRCC6	CHD1L	0.966	0.198
XRCC5	CHD1L	0.965	0.264
MACROD1	XPC	0.964	0.022
HLTF	PARP1	0.963	0.482857142857
RPA1	CHD1L	0.962	0.204
LIG3	RPA3	0.962	0.12
WRN	XRCC5	0.96	0.48
SSBP1	CLEC1B	0.96
XRCC6	LIG3	0.96	0.338
CHD1L	PARP1	0.958	0.470310125952
HLTF	RPA3	0.957	0.048
XRCC5	LIG3	0.955	0.306
PRIMPOL	RPA2	0.951
LIG3	RPA1	0.951	0.202
MACROD1	PARP2	0.95	0.034	structurally_consistent (dimer)
APLF	CETN2	0.949
XPA	SSBP1	0.948	0.062
SSRP1	MACROD1	0.947	0.04
XRCC1	CHD1L	0.943	0.102
XRCC1	RPA2	0.943	0.232
SSRP1	CHD1L	0.94	0.144
XRCC6	RPA4	0.937
XRCC6	XPC	0.932	0.314
RPA2	RPA4	0.931		mutually_exclusive (P35244)
PRIMPOL	SSBP1	0.926
CETN2	RPA2	0.923	0.088
RPA3	RNF146	0.92	0.148
LIG3	CHD1L	0.92	0.094
XRCC6	SSRP1	0.92	0.588
XRCC1	TDP1	0.918	0.172
RPA3	CETN2	0.915	0.082	structurally_consistent (dimer)
SSRP1	RNF146	0.915	0.106
SSRP1	XPC	0.914	0.184	structurally_consistent (dimer)
RNF146	RPA2	0.91	0.112
XRCC1	PARP2	0.908	0.07
XRCC5	PARP1	0.905	0.672	mutually_exclusive (P12956)
APLF	TDP1	0.904
SSRP1	RPA2	0.904	0.323
HLTF	RNF146	0.903	0.094
RPA2	CHD1L	0.9	0.082
SSRP1	LIG3	0.896	0.108
LIG3	CETN2	0.893	0.086
CETN2	PARP2	0.889	0.018	mutually_exclusive (Q9BQ69)
SSRP1	CETN2	0.884	0.062	structurally_consistent (Q01831)
RPA3	PARP2	0.883	0.078
XPA	RPA1	0.88	0.122
HLTF	POLB	0.878	0.036
RPA3	SSBP1	0.875	0.348
PNKP	TDP1	0.862	0.12
XRCC6	RNF146	0.862	0.136
XRCC5	RNF146	0.861	0.136
XPC	SSBP1	0.859	0.136
XRCC6	CETN2	0.858	0.154
PRIMPOL	RPA1	0.857
SSRP1	RPA1	0.855	0.398
XRCC5	XPC	0.853	0.292
XRCC5	RPA4	0.852
MACROD1	RPA1	0.841	0.052
HLTF	CETN2	0.838	0.038
RPA3	CHD1L	0.836	0.102
RPA1	RNF146	0.834	0.112
XRCC5	SSRP1	0.831	0.408
POLB	RPA1	0.825	0.112
XRCC5	HLTF	0.823	0.114
POLB	RPA2	0.823	0.1
APLF	CHD1L	0.818
XRCC6	RPA3	0.808	0.612
XRCC6	XRCC1	0.807	0.336
TDP1	CETN2	0.804	0.05
SSRP1	HLTF	0.795	0.186
XRCC6	POLB	0.794	0.302
HLTF	XRCC1	0.791	0.07
XPC	TDP1	0.787	0.05
PARP2	RPA4	0.786
TDP1	PARP2	0.785	0.092
XRCC5	MACROD1	0.779	0.186
SSRP1	PARP2	0.777	0.266
POLB	RPA3	0.737	0.106	structurally_consistent (dimer)
MACROD1	RPA3	0.734	0.052	mutually_exclusive (P41208)
WRN	LIG3	0.719	0.146
XRCC5	POLB	0.71	0.306
XRCC5	CETN2	0.704	0.104
WRN	XPC	0.687	0.126
SSRP1	RPA4	0.681
PNKP	PARP2	0.661	0.046
HLTF	PARP2	0.654	0.086
WRN	CHD1L	0.651	0.162
MACROD1	CETN2	0.642	0.032	structurally_consistent (dimer)
XRCC6	MACROD1	0.63	0.2
POLB	CETN2	0.628	0.14	mutually_exclusive (P35244)
PNKP	RPA2	0.624	0.1
XRCC6	RPA1	0.614	0.654
RPA1	PARP1	0.605	0.63
XRCC6	HLTF	0.561	0.106
RPA1	PARP2	0.555	0.11
XRCC5	PARP2	0.538	0.198
XRCC5	PNKP	0.532	0.336193548387
SSRP1	RPA3	0.516	0.368
XRCC5	RPA1	0.516	0.632
XPC	XRCC1	0.515	0.126
LIG3	RPAIN	0.512	0.1
PRIMPOL	RPA3	0.505
WRN	PARP2	0.488	0.17
XPC	RPAIN	0.469	0.062
TDP1	RPA1	0.465	0.11
RNF146	CETN2	0.458	0.052	structurally_consistent (Q01831)
TDP1	RPA3	0.457	0.034
XRCC1	RPA1	0.429	0.22
PARP2	PARP1	0.423	0.307277777778	mutually_exclusive (Q9BQ69)
CETN2	PARP1	0.422	0.1227	mutually_exclusive (Q9BQ69)
RPA1	CETN2	0.401	0.054
SSRP1	XRCC1	0.399	0.196
TDP1	RPA2	0.379	0.042
XRCC6	PNKP	0.375	0.308
XRCC1	CETN2	0.364	0.026	mutually_exclusive (P35244)
LIG3	RNF146	0.345	0.064
CETN2	RPA4	0.335
CETN2	CHD1L	0.335	0.032
XRCC5	RPA3	0.32	0.578
TDP1	PARP1	0.314	0.214
LIG3	MACROD1	0.304	0.036
APLF	PNKP	0.297
PNKP	PARP1	0.292	0.338764705882
WRN	PARP1	0.287	0.543322033898
CETN2	SSBP1	0.286	0.102
SSRP1	TDP1	0.284	0.187333333333
HLTF	RPAIN	0.283	0.078
SSBP1	PARP1	0.264	0.462
XRCC1	RPA3	0.253	0.098	structurally_consistent (dimer)
RPA3	PARP1	0.242	0.42
XRCC5	XRCC1	0.234	0.286
WRN	SSRP1	0.234	0.45
XRCC1	PARP1	0.23	0.434955555556
PARP2	RPAIN	0.204	0.088
SSRP1	RPAIN	0.195	0.094
SSBP1	PARP2	0.17	0.09
WRN	RPA2	0.169	0.198
CETN2	RPAIN	0.167	0.214
WRN	APLF	0.164
XRCC1	RNF146	0.164	0.14
WRN	RPA1	0.16	0.296
WRN	XRCC1	0.157	0.13
WRN	HLTF	0.13	0.318
POLB	CHD1L	0.115	0.064
XRCC6	TDP1	0.114	0.365333333333
XPC	PNKP	0.111	0.108
WRN	RPA3	0.107	0.136
HLTF	TDP1	0.095	0.06
TDP1	CHD1L	0.094	0.17
SSBP1	RPAIN	0.091	0.076
XRCC5	TDP1	0.078	0.278
XPC	XPA	0.076	0.094
XRCC5	RPAIN	0.073	0.136
WRN	CETN2	0.071	0.092
PNKP	RPA1	0.071	0.106
HLTF	MACROD1	0.067	0.036
XRCC6	RPAIN	0.067	0.232
XPA	PARP1	0.059	0.212275862069
APLF	SSBP1	0.058
HLTF	PNKP	0.053	0.042
LIG3	SSBP1	0.042	0.094
SSRP1	PNKP	0.04	0.104
PNKP	CETN2	0.034	0.052
HLTF	SSBP1	0.031	0.05
XRCC5	SSBP1	0.031	0.332
XPA	CETN2	0.027	0.078
HLTF	RPA4	0.024
HLTF	XPA	0.021	0.078
XRCC1	SSBP1	0.016	0.156
SSRP1	XPA	0.016	0.096
PNKP	RPA3	0.015	0.056
XRCC6	XPA	0.014	0.256
WRN	TDP1	0.014	0.246
RNF146	SSBP1	0.013	0.14
WRN	PNKP	0.008	0.08
XRCC6	SSBP1	0.008	0.374
CLEC1B	PARP1	0.006
XRCC5	XPA	0.004	0.192	structurally_consistent (dimer)
MACROD1	SSBP1	0.004	0.104
PRIMPOL	XRCC5	0.004
POLB	SSBP1	0.004	0.162
SSBP1	CHD1L	0.004	0.18
RPA1	CLEC1B	0.004
PNKP	SSBP1	0.003	0.048
XRCC6	CLEC1B	0.002
TDP1	SSBP1	0.001	0.046
XRCC5	CLEC1B	0.001
SSRP1	SSBP1	0.001	0.214

Related Complexes

Genename	Complexes
SSBP1	huMAP3_03449.1 huMAP3_05330.1 huMAP3_10213.1 huMAP3_13432.1 huMAP3_13854.1 huMAP3_14846.1
XPC	huMAP3_01511.1 huMAP3_02570.1 huMAP3_06287.1 huMAP3_08413.1 huMAP3_09211.1 huMAP3_09858.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
HLTF	huMAP3_01511.1 huMAP3_02570.1 huMAP3_06287.1 huMAP3_08422.1 huMAP3_09432.1 huMAP3_09858.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
CLEC1B	huMAP3_05330.1 huMAP3_13432.1 huMAP3_13854.1 huMAP3_14846.1
RPA3	huMAP3_02103.1 huMAP3_07481.1 huMAP3_08325.1 huMAP3_08422.1 huMAP3_09432.1 huMAP3_10578.1 huMAP3_13854.1 huMAP3_14846.1
APLF	huMAP3_00669.1 huMAP3_02384.1 huMAP3_07457.1 huMAP3_09211.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
PNKP	huMAP3_01586.1 huMAP3_02384.1 huMAP3_07457.1 huMAP3_08193.1 huMAP3_09211.1 huMAP3_10578.1 huMAP3_11158.1 huMAP3_13854.1 huMAP3_14846.1
RPA4	huMAP3_07481.1 huMAP3_08325.1 huMAP3_08422.1 huMAP3_09432.1 huMAP3_10578.1 huMAP3_13854.1 huMAP3_14846.1
SSRP1	huMAP3_00545.1 huMAP3_05655.1 huMAP3_09466.1 huMAP3_10862.1 huMAP3_12711.1 huMAP3_13854.1 huMAP3_14846.1
RPA2	huMAP3_03503.1 huMAP3_07481.1 huMAP3_08325.1 huMAP3_08422.1 huMAP3_09432.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
WRN	huMAP3_00033.1 huMAP3_03073.1 huMAP3_07080.1 huMAP3_07130.1 huMAP3_07707.1 huMAP3_09649.1 huMAP3_10143.1 huMAP3_10513.1 huMAP3_10639.1 huMAP3_13816.1 huMAP3_14174.1 huMAP3_14846.1 huMAP3_15006.1
RNF146	huMAP3_02570.1 huMAP3_06287.1 huMAP3_08413.1 huMAP3_09211.1 huMAP3_09858.1 huMAP3_10578.1 huMAP3_13854.1 huMAP3_14846.1
RPA1	huMAP3_02103.1 huMAP3_07481.1 huMAP3_08325.1 huMAP3_08422.1 huMAP3_09432.1 huMAP3_10578.1 huMAP3_13854.1 huMAP3_14846.1
TDP1	huMAP3_01586.1 huMAP3_02384.1 huMAP3_08193.1 huMAP3_09211.1 huMAP3_10578.1 huMAP3_11158.1 huMAP3_11442.1 huMAP3_12122.1 huMAP3_13854.1 huMAP3_14846.1
PARP1	huMAP3_09432.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
CHD1L	huMAP3_07080.1 huMAP3_08413.1 huMAP3_09211.1 huMAP3_10513.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
CETN2	huMAP3_02830.1 huMAP3_05949.1 huMAP3_11442.1 huMAP3_12122.1 huMAP3_14846.1 huMAP3_14860.1
XRCC5	huMAP3_00503.1 huMAP3_03073.1 huMAP3_07080.1 huMAP3_07130.1 huMAP3_07707.1 huMAP3_09649.1 huMAP3_10513.1 huMAP3_10639.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
PARP2	huMAP3_06287.1 huMAP3_06600.1 huMAP3_08413.1 huMAP3_09211.1 huMAP3_09858.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
MACROD1	huMAP3_01511.1 huMAP3_03503.1 huMAP3_07481.1 huMAP3_08422.1 huMAP3_08778.1 huMAP3_09432.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13399.1 huMAP3_13854.1 huMAP3_14846.1
XRCC6	huMAP3_00503.1 huMAP3_03073.1 huMAP3_07080.1 huMAP3_07130.1 huMAP3_07707.1 huMAP3_09649.1 huMAP3_10513.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1
RPAIN	huMAP3_07481.1 huMAP3_08325.1 huMAP3_08422.1 huMAP3_09432.1 huMAP3_10578.1 huMAP3_13854.1 huMAP3_14846.1
POLB	huMAP3_01586.1 huMAP3_02384.1 huMAP3_07457.1 huMAP3_08193.1 huMAP3_09211.1 huMAP3_10578.1 huMAP3_11158.1 huMAP3_13854.1 huMAP3_14846.1
XRCC1	huMAP3_01586.1 huMAP3_02384.1 huMAP3_07457.1 huMAP3_08193.1 huMAP3_09211.1 huMAP3_10578.1 huMAP3_11158.1 huMAP3_13854.1 huMAP3_14846.1
XPA	huMAP3_01917.1 huMAP3_03121.1 huMAP3_09920.1 huMAP3_10527.1 huMAP3_11825.1 huMAP3_13432.1 huMAP3_13854.1 huMAP3_14846.1
PRIMPOL	huMAP3_00318.1 huMAP3_04058.1 huMAP3_06720.1 huMAP3_07164.1 huMAP3_07715.1 huMAP3_10013.1 huMAP3_13053.1 huMAP3_13432.1 huMAP3_13854.1 huMAP3_14846.1
LIG3	huMAP3_00669.1 huMAP3_01586.1 huMAP3_02384.1 huMAP3_07457.1 huMAP3_08193.1 huMAP3_09211.1 huMAP3_10578.1 huMAP3_10730.1 huMAP3_13854.1 huMAP3_14846.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_14846.1

Complex Portal: CPX-24023