hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14850.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LZTS1 | Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1) | 5 | UniProt NCBI |
| PDE9A | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35) | 5 | UniProt NCBI |
| PDE8A | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53) | 5 | UniProt NCBI |
| PDE8B | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) | 5 | UniProt NCBI |
| SGK3 | Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) | 5 | UniProt NCBI |
| FSTL5 | Follistatin-related protein 5 (Follistatin-like protein 5) | 4 | UniProt NCBI |
| AMHR2 | Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) | 5 | UniProt NCBI |
| RFTN1 | Raftlin (Cell migration-inducing gene 2 protein) (Raft-linking protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004114 | 0.00364711882004 | 0.375 | PDE8B PDE9A PDE8A | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| GO:0004112 | 0.0043754188034 | 0.375 | PDE8B PDE9A PDE8A | cyclic-nucleotide phosphodiesterase activity |
| WP:WP4222 | 0.016652650636 | 0.25 | PDE9A PDE8A | Phosphodiesterases in neuronal function |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SGK3 | AMHR2 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PDE8B | PDE8A | 0.979 | 0.13 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| PDE8A | PDE9A | 0.947 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PDE9A | LZTS1 | 0.916 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDE8A | LZTS1 | 0.912 | 0.16 | bioplex_WMM bioplex3_WMM WMM_only |
| RFTN1 | AMHR2 | 0.904 | bioplex3_WMM WMM_only | |
| PDE8A | AMHR2 | 0.902 | bioplex3_WMM WMM_only | |
| LZTS1 | FSTL5 | 0.902 | bioplex3_WMM WMM_only | |
| PDE9A | AMHR2 | 0.902 | bioplex3_WMM WMM_only | |
| PDE9A | RFTN1 | 0.896 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDE8A | RFTN1 | 0.869 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| LZTS1 | RFTN1 | 0.868 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
| LZTS1 | AMHR2 | 0.717 | bioplex3_WMM WMM_only |
Related Complexes