hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14852.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HAUS7 | HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | 5 | UniProt NCBI |
| SPRYD7 | SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein) (CLL deletion region gene 6 protein) | 5 | UniProt NCBI |
| HAUS8 | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | 5 | UniProt NCBI |
| HAUS3 | HAUS augmin-like complex subunit 3 | 5 | UniProt NCBI |
| HAUS2 | HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27) | 5 | UniProt NCBI |
| HAUS6 | HAUS augmin-like complex subunit 6 | 5 | UniProt NCBI |
| RNF10 | E3 ubiquitin-protein ligase RNF10 (EC 2.3.2.27) (RING finger protein 10) | 5 | UniProt NCBI |
| HAUS4 | HAUS augmin-like complex subunit 4 | 5 | UniProt NCBI |
| HAUS5 | HAUS augmin-like complex subunit 5 | 5 | UniProt NCBI |
| HAUS1 | HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) | 5 | UniProt NCBI |
| BEX5 | Protein BEX5 (Brain-expressed X-linked protein 5) (NGFRAP1-like protein 1) (Nerve growth factor receptor-associated protein 2) | 5 | UniProt NCBI |
| ADAMTS3 | A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070652 | 4.80327387602e-22 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | HAUS complex |
| GO:1990498 | 1.44031747814e-18 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | mitotic spindle microtubule |
| CORUM:6435 | 4.1567655224e-18 | 0.5 | HAUS7 HAUS5 HAUS1 HAUS6 HAUS2 HAUS8 | HAUS augmin-like complex |
| GO:0010968 | 1.16511970707e-17 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of microtubule nucleation |
| REAC:R-HSA-380284 | 1.47828855014e-14 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-380259 | 1.47828855014e-14 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-8854518 | 2.15050592347e-14 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | AURKA Activation by TPX2 |
| REAC:R-HSA-380287 | 6.01712129547e-14 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Centrosome maturation |
| REAC:R-HSA-380270 | 6.01712129547e-14 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Recruitment of mitotic centrosome proteins and complexes |
| GO:0007020 | 8.4386109784e-14 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule nucleation |
| REAC:R-HSA-2565942 | 1.0109862502e-13 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-380320 | 1.98343513399e-13 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-5620912 | 2.60396496913e-13 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Anchoring of the basal body to the plasma membrane |
| GO:0031113 | 3.57608670482e-13 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of microtubule polymerization |
| GO:0005876 | 7.12363790473e-12 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | spindle microtubule |
| GO:0031110 | 1.10715031837e-11 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of microtubule polymerization or depolymerization |
| GO:0046785 | 1.51766695275e-11 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule polymerization |
| REAC:R-HSA-5617833 | 8.67855027065e-11 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Cilium Assembly |
| REAC:R-HSA-69275 | 8.67855027065e-11 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | G2/M Transition |
| REAC:R-HSA-453274 | 9.45143931064e-11 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Mitotic G2-G2/M phases |
| GO:0051225 | 1.02943935027e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | spindle assembly |
| REAC:R-HSA-68877 | 1.11794696965e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Mitotic Prometaphase |
| GO:0031109 | 2.22664437748e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule polymerization or depolymerization |
| GO:0007098 | 3.42056331403e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | centrosome cycle |
| GO:0005875 | 4.80974325912e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule associated complex |
| GO:0070507 | 7.57227521313e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of microtubule cytoskeleton organization |
| GO:0032271 | 9.12781791005e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of protein polymerization |
| GO:0031023 | 9.70498157097e-10 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule organizing center organization |
| REAC:R-HSA-1852241 | 1.78971078533e-09 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Organelle biogenesis and maintenance |
| GO:0072686 | 3.92145740515e-09 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | mitotic spindle |
| GO:0007051 | 4.56596531606e-09 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | spindle organization |
| GO:0032886 | 2.14402749983e-08 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of microtubule-based process |
| GO:0051258 | 2.5250337573e-08 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | protein polymerization |
| REAC:R-HSA-68886 | 2.75892351906e-08 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | M Phase |
| GO:1902903 | 2.75801643603e-07 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of supramolecular fiber organization |
| GO:0005874 | 3.01519721395e-07 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule |
| REAC:R-HSA-69278 | 3.16405557461e-07 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Cell Cycle, Mitotic |
| GO:0043254 | 4.90680156676e-07 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of protein-containing complex assembly |
| GO:0005819 | 6.98418745652e-07 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | spindle |
| GO:0140694 | 8.61290206603e-07 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | non-membrane-bounded organelle assembly |
| GO:0007059 | 1.19696277631e-06 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | chromosome segregation |
| REAC:R-HSA-1640170 | 1.62447510678e-06 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | Cell Cycle |
| GO:0097435 | 3.31417095168e-06 | 0.75 | HAUS3 ADAMTS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | supramolecular fiber organization |
| GO:0051493 | 4.20744962727e-06 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of cytoskeleton organization |
| GO:0099513 | 9.56200052403e-06 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | polymeric cytoskeletal fiber |
| GO:0000226 | 3.48323504383e-05 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule cytoskeleton organization |
| GO:0005813 | 7.38097818076e-05 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | centrosome |
| GO:0099512 | 9.16079638887e-05 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | supramolecular fiber |
| GO:0099081 | 0.000101119084683 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | supramolecular polymer |
| GO:0005815 | 0.000281176090774 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule organizing center |
| GO:0044087 | 0.000432107959287 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of cellular component biogenesis |
| GO:0007017 | 0.000519141360944 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule-based process |
| GO:0070925 | 0.000797774168729 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | organelle assembly |
| GO:0099080 | 0.00310763574538 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | supramolecular complex |
| GO:0033043 | 0.0039085685374 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | regulation of organelle organization |
| GO:0022402 | 0.00771945982259 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | cell cycle process |
| GO:0015630 | 0.0100620199596 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | microtubule cytoskeleton |
| GO:0007010 | 0.0191816160898 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | cytoskeleton organization |
| GO:0065003 | 0.0338363465564 | 0.666666666667 | HAUS3 HAUS5 HAUS7 HAUS4 HAUS8 HAUS6 HAUS2 HAUS1 | protein-containing complex assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| HAUS7 | HAUS8 | 1.0 | 0.35 |
| HAUS7 | HAUS4 | 1.0 | 0.274 |
| HAUS7 | HAUS5 | 1.0 | 0.332 |
| HAUS7 | HAUS3 | 1.0 | 0.222 |
| HAUS7 | HAUS1 | 1.0 | 0.238 |
| HAUS7 | HAUS6 | 1.0 | 0.208 |
| HAUS7 | HAUS2 | 1.0 | 0.686 |
| HAUS4 | HAUS5 | 1.0 | 0.392 |
| HAUS6 | HAUS5 | 1.0 | 0.122 |
| HAUS2 | HAUS5 | 0.999 | 0.348 |
| HAUS3 | HAUS5 | 0.999 | 0.188 |
| HAUS4 | HAUS1 | 0.999 | 0.33 |
| HAUS3 | HAUS4 | 0.999 | 0.352 |
| HAUS8 | HAUS2 | 0.999 | 0.324 |
| HAUS3 | HAUS2 | 0.999 | 0.45 |
| HAUS2 | HAUS6 | 0.998 | 0.338 |
| HAUS8 | HAUS4 | 0.998 | 0.364 |
| HAUS2 | HAUS1 | 0.998 | 0.284 |
| HAUS8 | HAUS6 | 0.998 | 0.374 |
| HAUS3 | HAUS1 | 0.998 | 0.12 |
| HAUS2 | HAUS4 | 0.998 | 0.474 |
| HAUS8 | HAUS5 | 0.997 | 0.268 |
| HAUS6 | HAUS4 | 0.996 | 0.244 |
| HAUS3 | HAUS6 | 0.995 | 0.12 |
| HAUS6 | HAUS1 | 0.995 | 0.114 |
| HAUS8 | HAUS3 | 0.993 | 0.288 |
| HAUS7 | SPRYD7 | 0.993 | 0.072 |
| HAUS8 | HAUS1 | 0.99 | 0.292 |
| HAUS3 | RNF10 | 0.988 | 0.104 |
| HAUS5 | HAUS1 | 0.987 | 0.35 |
| HAUS8 | RNF10 | 0.953 | 0.26 |
| RNF10 | HAUS4 | 0.953 | 0.168 |
| HAUS2 | SPRYD7 | 0.932 | 0.098 |
| HAUS3 | SPRYD7 | 0.908 | 0.052 |
| RNF10 | ADAMTS3 | 0.902 | |
| HAUS4 | SPRYD7 | 0.886 | 0.1 |
| HAUS6 | SPRYD7 | 0.873 | 0.044 |
| HAUS8 | SPRYD7 | 0.866 | 0.106 |
| HAUS1 | SPRYD7 | 0.856 | 0.09 |
| HAUS3 | BEX5 | 0.854 | |
| HAUS2 | RNF10 | 0.749 | 0.142 |
| HAUS6 | BEX5 | 0.729 | |
| HAUS8 | BEX5 | 0.646 | |
| HAUS5 | BEX5 | 0.619 | |
| RNF10 | HAUS1 | 0.615 | 0.204 |
| RNF10 | HAUS5 | 0.581 | 0.134 |
| HAUS4 | BEX5 | 0.565 | |
| HAUS6 | RNF10 | 0.406 | 0.122 |
| HAUS5 | SPRYD7 | 0.365 | 0.074 |
| HAUS7 | RNF10 | 0.224 | 0.216 |
| HAUS7 | BEX5 | 0.102 | |
| HAUS1 | BEX5 | 0.079 | |
| HAUS2 | BEX5 | 0.079 |
Related Complexes