hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14859.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMEM115 | Transmembrane protein 115 (Placental protein 6) (Protein PL6) | 5 | UniProt NCBI |
| RAB5IF | GEL complex subunit OPTI (Obligate partner of TMCO1 insertase) (Rab5-interacting protein) (RIP5) (Respirasome Complex Assembly Factor 1) | 5 | UniProt NCBI |
| SLC49A4 | Solute carrier family 49 member 4 (Disrupted in renal cancer protein 2) (Disrupted in renal carcinoma protein 2) | 5 | UniProt NCBI |
| TLCD1 | TLC domain-containing protein 1 (Calfacilitin) | 5 | UniProt NCBI |
| ORMDL1 | ORM1-like protein 1 (Adoplin-1) | 5 | UniProt NCBI |
| SLC22A9 | Organic anion transporter 7 (OAT7) (Organic anion/short-chain fatty acid exchanger) (Solute carrier family 22 member 9) | 5 | UniProt NCBI |
| EIF2D | Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin) | 5 | UniProt NCBI |
| ABCC3 | ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3) | 5 | UniProt NCBI |
| SLC22A5 | Organic cation/carnitine transporter 2 (High-affinity sodium-dependent carnitine cotransporter) (Solute carrier family 22 member 5) | 5 | UniProt NCBI |
| SLC18A2 | Synaptic vesicular amine transporter (Monoamine transporter) (Solute carrier family 18 member 2) (Vesicular amine transporter 2) (VAT2) | 5 | UniProt NCBI |
| SLC22A4 | Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (ETTh) (Organic cation/carnitine transporter 1) (OCTN1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-425366 | 0.00188588147319 | 0.272727272727 | SLC22A5 SLC22A4 SLC18A2 | Transport of bile salts and organic acids, metal ions and amine compounds |
| REAC:R-HSA-549127 | 0.00372670794354 | 0.181818181818 | SLC22A5 SLC22A4 | Organic cation transport |
| REAC:R-HSA-549132 | 0.00731130585838 | 0.181818181818 | SLC22A5 SLC22A4 | Organic cation/anion/zwitterion transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLC22A9 | TMEM115 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC22A9 | ORMDL1 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC49A4 | SLC22A4 | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A4 | ABCC3 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A9 | SLC22A5 | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC22A4 | TMEM115 | 0.982 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC18A2 | ORMDL1 | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A9 | RAB5IF | 0.962 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ORMDL1 | RAB5IF | 0.955 | 0.076 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| SLC22A4 | SLC22A5 | 0.948 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A4 | ORMDL1 | 0.942 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A4 | RAB5IF | 0.939 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A4 | EIF2D | 0.915 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A4 | TLCD1 | 0.846 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC18A2 | TLCD1 | 0.838 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TMEM115 | ORMDL1 | 0.497 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC49A4 | ABCC3 | 0.415 | 0.056 | bioplex3_WMM WMM_only |
| ABCC3 | EIF2D | 0.415 | 0.03 | bioplex3_WMM WMM_only |
| SLC49A4 | EIF2D | 0.415 | 0.026 | bioplex3_WMM WMM_only |
| SLC22A5 | RAB5IF | 0.37 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMEM115 | EIF2D | 0.274 | 0.03 | bioplex3_WMM WMM_only |
| SLC22A5 | ORMDL1 | 0.262 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMEM115 | RAB5IF | 0.218 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC22A5 | EIF2D | 0.113 | bioplex3_WMM WMM_only | |
| ABCC3 | TMEM115 | 0.113 | 0.048 | bioplex3_WMM WMM_only |
| SLC22A5 | TMEM115 | 0.113 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| SLC22A5 | TLCD1 | 0.1 | bioplex3_WMM WMM_only | |
| TLCD1 | EIF2D | 0.095 | 0.04 | bioplex3_WMM WMM_only |
| EIF2D | RAB5IF | 0.095 | 0.05 | bioplex3_WMM WMM_only |
| TLCD1 | RAB5IF | 0.085 | 0.104 | bioplex3_WMM WMM_only |
| TLCD1 | ORMDL1 | 0.08 | 0.072 | bioplex3_WMM gupta_WMM WMM_only |
| SLC49A4 | TMEM115 | 0.079 | 0.148 | bioplex3_WMM WMM_only |
| ABCC3 | TLCD1 | 0.079 | 0.042 | bioplex3_WMM WMM_only |
| SLC49A4 | TLCD1 | 0.079 | 0.086 | bioplex3_WMM WMM_only |
| ABCC3 | ORMDL1 | 0.079 | 0.034 | bioplex3_WMM WMM_only |
| TMEM115 | TLCD1 | 0.079 | 0.11 | bioplex3_WMM WMM_only |
| SLC49A4 | SLC22A5 | 0.078 | bioplex3_WMM WMM_only | |
| ABCC3 | RAB5IF | 0.078 | 0.038 | bioplex3_WMM WMM_only |
| SLC49A4 | RAB5IF | 0.078 | 0.094 | bioplex3_WMM WMM_only |
| ABCC3 | SLC22A5 | 0.078 | bioplex3_WMM WMM_only | |
| ORMDL1 | EIF2D | 0.078 | 0.016 | bioplex3_WMM WMM_only |
| SLC49A4 | ORMDL1 | 0.076 | 0.086 | bioplex3_WMM WMM_only |
Related Complexes