hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14883.1
Complex Portal: CPX-19422
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MIEN1 | Migration and invasion enhancer 1 (HBV X-transactivated gene 4 protein) (HBV XAg-transactivated protein 4) (Protein C35) | 5 | UniProt NCBI |
| DPP3 | Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) | 5 | UniProt NCBI |
| MAML1 | Mastermind-like protein 1 (Mam-1) | 5 | UniProt NCBI |
| RGS19 | Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) | 5 | UniProt NCBI |
| CFAP141 | Cilia- and flagella-associated protein 141 | 3 | UniProt NCBI |
| TTC7B | Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1) | 5 | UniProt NCBI |
| METTL26 | Methyltransferase-like 26 | 3 | UniProt NCBI |
| RGS20 | Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-418597 | 0.0328938418336 | 0.25 | RGS20 RGS19 | G alpha (z) signalling events |
| CORUM:6211 | 0.0499436884912 | 0.125 | RGS20 | RSG20-MT1-MT2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RGS19 | RGS20 | 0.993 | 0.17 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| METTL26 | RGS20 | 0.984 | 0.056 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DPP3 | RGS20 | 0.981 | 0.118 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TTC7B | RGS20 | 0.966 | 0.178 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CFAP141 | DPP3 | 0.919 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| RGS20 | MAML1 | 0.853 | 0.13 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| METTL26 | MIEN1 | 0.828 | 0.058 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DPP3 | METTL26 | 0.283 | 0.078 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DPP3 | TTC7B | 0.259 | 0.048 | bioplex_WMM bioplex3_WMM WMM_only | |
| METTL26 | MAML1 | 0.25 | 0.034 | bioplex3_WMM WMM_only | |
| RGS19 | METTL26 | 0.146 | 0.054 | bioplex3_WMM WMM_only | |
| TTC7B | METTL26 | 0.113 | 0.048 | bioplex3_WMM WMM_only | |
| TTC7B | MAML1 | 0.078 | 0.158 | bioplex3_WMM WMM_only | |
| DPP3 | MAML1 | 0.076 | 0.096 | bioplex3_WMM WMM_only | |
| DPP3 | RGS19 | 0.059 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| RGS19 | MAML1 | 0.055 | 0.13 | bioplex3_WMM WMM_only | |
| RGS19 | TTC7B | 0.053 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes