hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14884.1
Complex Portal: CPX-17858
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CFAP36 | Cilia- and flagella-associated protein 36 (Coiled-coil domain-containing protein 104) | 5 | UniProt NCBI |
| ARL3 | ADP-ribosylation factor-like protein 3 | 5 | UniProt NCBI |
| WDR17 | WD repeat-containing protein 17 | 2 | UniProt NCBI |
| ARL2BP | ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1) | 5 | UniProt NCBI |
| TTC5 | Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap) | 5 | UniProt NCBI |
| EML1 | Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1) | 5 | UniProt NCBI |
| EML4 | Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120) | 5 | UniProt NCBI |
| ARL2 | ADP-ribosylation factor-like protein 2 | 5 | UniProt NCBI |
| EML6 | Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like) | 3 | UniProt NCBI |
| EML2 | Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-83936 | 0.0036548283771 | 0.2 | ARL2 ARL2BP | Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane |
| GO:0008017 | 0.00677756699018 | 0.5 | ARL3 EML6 EML2 EML1 EML4 | microtubule binding |
| GO:0015631 | 0.0382006985198 | 0.5 | ARL3 EML6 EML2 EML1 EML4 | tubulin binding |
| REAC:R-HSA-425397 | 0.0499343626014 | 0.2 | ARL2 ARL2BP | Transport of vitamins, nucleosides, and related molecules |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EML4 | EML1 | 1.0 | 0.088 |
mutually_exclusive (Q13509)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| CFAP36 | ARL2 | 0.999 | 0.036 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| EML1 | EML2 | 0.997 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ARL2 | ARL2BP | 0.995 | 0.006 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
| EML4 | EML2 | 0.99 |
mutually_exclusive (Q9BVA1)
|
hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ARL3 | ARL2BP | 0.99 | 0.038 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| ARL2 | EML2 | 0.963 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ARL2 | TTC5 | 0.934 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARL2 | WDR17 | 0.915 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| EML2 | TTC5 | 0.884 | bioplex_WMM bioplex3_WMM WMM_only | ||
| EML4 | TTC5 | 0.871 | 0.026 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARL3 | CFAP36 | 0.847 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ARL2 | EML1 | 0.834 | 0.012 | bioplex_WMM bioplex3_WMM WMM_only | |
| EML6 | EML2 | 0.81 | bioplex_WMM bioplex3_WMM WMM_only | ||
| EML1 | TTC5 | 0.789 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only | |
| CFAP36 | WDR17 | 0.415 | bioplex3_WMM WMM_only | ||
| ARL2 | EML4 | 0.383 | 0.106 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| ARL3 | ARL2 | 0.353 | 0.062 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| ARL2 | EML6 | 0.3 | bioplex_WMM bioplex3_WMM WMM_only | ||
| EML6 | EML1 | 0.291 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CFAP36 | ARL2BP | 0.274 | 0.072 | bioplex3_WMM WMM_only | |
| ARL2BP | WDR17 | 0.274 | bioplex3_WMM WMM_only | ||
| EML6 | EML4 | 0.251 | bioplex_WMM bioplex3_WMM WMM_only | ||
| EML6 | TTC5 | 0.157 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ARL2BP | EML2 | 0.022 | bioplex3_HCT116 WMM_only | ||
| ARL3 | WDR17 | 0.021 | WMM_only boldt_WMM | ||
| ARL3 | EML2 | 0.009 | bioplex3_WMM WMM_only | ||
| ARL3 | EML6 | 0.008 | WMM_only boldt_WMM | ||
| CFAP36 | EML1 | 0.006 | 0.066 | fraction | |
| ARL3 | EML4 | 0.005 | 0.046 | bioplex3_WMM gupta_WMM WMM_only | |
| CFAP36 | EML4 | 0.004 | 0.04 | youn_WMM gupta_WMM fraction |
Related Complexes