hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14886.1
Complex Portal: CPX-15911
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ARHGEF7 | Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) | 5 | UniProt   NCBI |
TNK2 | Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2) | 5 | UniProt   NCBI |
WASL | Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP) | 5 | UniProt   NCBI |
PAK1 | Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK) | 5 | UniProt   NCBI |
WIPF2 | WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein) | 5 | UniProt   NCBI |
SH3PXD2B | SH3 and PX domain-containing protein 2B (Adapter protein HOFI) (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) | 5 | UniProt   NCBI |
GIT1 | ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1) | 5 | UniProt   NCBI |
GIT2 | ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2) | 5 | UniProt   NCBI |
CASKIN2 | Caskin-2 (CASK-interacting protein 2) | 3 | UniProt   NCBI |
SHB | SH2 domain-containing adapter protein B | 5 | UniProt   NCBI |
WIPF3 | WAS/WASL-interacting protein family member 3 (Corticosteroids and regional expression protein 16 homolog) | 4 | UniProt   NCBI |
CBLB | E3 ubiquitin-protein ligase CBL-B (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56) (RING-type E3 ubiquitin transferase CBL-B) (SH3-binding protein CBL-B) (Signal transduction protein CBL-B) | 5 | UniProt   NCBI |
DOK1 | Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62) | 5 | UniProt   NCBI |
TAX1BP3 | Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1) | 5 | UniProt   NCBI |
CBL | E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL) | 5 | UniProt   NCBI |
NCK1 | SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha) | 5 | UniProt   NCBI |
WIPF1 | WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein) | 5 | UniProt   NCBI |
ARHGEF6 | Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6) | 5 | UniProt   NCBI |
PIK3AP1 | Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) | 5 | UniProt   NCBI |
NCK2 | Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-9013148 | 5.06575039217e-12 | 0.473684210526 | PAK1 WASL GIT2 WIPF2 GIT1 ARHGEF7 ARHGEF6 WIPF3 WIPF1 | CDC42 GTPase cycle |
  REAC:R-HSA-9013149 | 4.04378441589e-11 | 0.473684210526 | PAK1 WASL GIT2 WIPF2 GIT1 ARHGEF7 ARHGEF6 WIPF3 WIPF1 | RAC1 GTPase cycle |
  REAC:R-HSA-9013424 | 9.53819302778e-10 | 0.315789473684 | PAK1 WASL GIT2 GIT1 ARHGEF7 NCK2 | RHOV GTPase cycle |
  REAC:R-HSA-9013420 | 1.36402950153e-09 | 0.315789473684 | PAK1 GIT2 GIT1 ARHGEF6 NCK2 ARHGEF7 | RHOU GTPase cycle |
  REAC:R-HSA-9012999 | 4.03295104733e-09 | 0.526315789474 | PAK1 WASL GIT2 WIPF2 GIT1 ARHGEF7 ARHGEF6 NCK2 WIPF3 WIPF1 | RHO GTPase cycle |
  KEGG:04144 | 1.3070006217e-08 | 0.421052631579 | WASL GIT2 WIPF2 WIPF1 GIT1 CBLB WIPF3 CBL | Endocytosis |
  REAC:R-HSA-9013409 | 1.33062080725e-08 | 0.315789473684 | PAK1 WASL GIT2 WIPF2 GIT1 ARHGEF7 | RHOJ GTPase cycle |
  REAC:R-HSA-194315 | 1.44732118618e-08 | 0.578947368421 | PAK1 WASL GIT2 WIPF2 GIT1 ARHGEF7 ARHGEF6 NCK2 TAX1BP3 WIPF3 WIPF1 | Signaling by Rho GTPases |
  REAC:R-HSA-9716542 | 1.83326331085e-08 | 0.578947368421 | PAK1 WASL GIT2 WIPF2 GIT1 ARHGEF7 ARHGEF6 NCK2 TAX1BP3 WIPF3 WIPF1 | Signaling by Rho GTPases, Miro GTPases and RHOBTB3 |
  CORUM:6928 | 7.10994807657e-08 | 0.157894736842 | PAK1 ARHGEF7 GIT2 | ARHGEF7-GIT2-PAK1 complex |
  REAC:R-HSA-162582 | 8.44537725073e-08 | 0.789473684211 | PAK1 WASL PIK3AP1 NCK2 GIT2 TAX1BP3 WIPF2 WIPF1 GIT1 ARHGEF7 ARHGEF6 DOK1 SHB WIPF3 CBL | Signal Transduction |
  CORUM:6341 | 2.84164363312e-07 | 0.157894736842 | PAK1 ARHGEF7 GIT1 | GIT1-ARHGEF7-PAK1-PXN complex |
  CORUM:6778 | 2.84164363312e-07 | 0.157894736842 | PAK1 ARHGEF7 GIT1 | SCRIB-GIT1-ARHGEF7-PAK1 complex |
  CORUM:6779 | 2.84164363312e-07 | 0.157894736842 | PAK1 ARHGEF7 GIT1 | SCRIB-GIT1-ARHGEF7-PAK1 complex |
  KEGG:05135 | 3.02357061881e-07 | 0.315789473684 | WIPF1 GIT2 WIPF2 ARHGEF7 WIPF3 WASL | Yersinia infection |
  REAC:R-HSA-3928664 | 1.10057701507e-06 | 0.210526315789 | PAK1 NCK2 ARHGEF7 GIT1 | Ephrin signaling |
  REAC:R-HSA-9013406 | 1.73145015968e-06 | 0.263157894737 | PAK1 GIT1 ARHGEF7 GIT2 WASL | RHOQ GTPase cycle |
  REAC:R-HSA-2029482 | 2.29919373407e-06 | 0.263157894737 | WIPF1 PAK1 WIPF3 WASL WIPF2 | Regulation of actin dynamics for phagocytic cup formation |
  KEGG:05130 | 2.64371876876e-06 | 0.315789473684 | PAK1 WIPF1 WIPF2 NCK2 WIPF3 WASL | Pathogenic Escherichia coli infection |
  REAC:R-HSA-2029480 | 1.24851662498e-05 | 0.263157894737 | WIPF1 PAK1 WIPF3 WASL WIPF2 | Fcgamma receptor (FCGR) dependent phagocytosis |
  REAC:R-HSA-2682334 | 1.60850171095e-05 | 0.263157894737 | NCK2 PAK1 GIT1 ARHGEF7 WASL | EPH-Ephrin signaling |
  REAC:R-HSA-5663213 | 2.76322577389e-05 | 0.210526315789 | WIPF1 WIPF3 WASL WIPF2 | RHO GTPases Activate WASPs and WAVEs |
  WP:WP437 | 0.000112926505902 | 0.263157894737 | NCK2 TNK2 CBL CBLB PAK1 | EGF EGFR signaling pathway |
  KEGG:04012 | 0.000143568966818 | 0.210526315789 | PAK1 NCK2 CBLB CBL | ErbB signaling pathway |
  REAC:R-HSA-9664417 | 0.000171769261098 | 0.210526315789 | WIPF1 WIPF3 WASL WIPF2 | Leishmania phagocytosis |
  REAC:R-HSA-9664407 | 0.000171769261098 | 0.210526315789 | WIPF1 WIPF3 WASL WIPF2 | Parasite infection |
  REAC:R-HSA-9664422 | 0.000171769261098 | 0.210526315789 | WIPF1 WIPF3 WASL WIPF2 | FCGR3A-mediated phagocytosis |
  CORUM:930 | 0.000183206632644 | 0.105263157895 | GIT1 ARHGEF7 | SCRIB-GIT1-ARHGEF7 complex |
  KEGG:04810 | 0.000233546205011 | 0.263157894737 | PAK1 GIT1 ARHGEF7 ARHGEF6 WASL | Regulation of actin cytoskeleton |
  WP:WP673 | 0.000399172840027 | 0.210526315789 | PAK1 NCK2 CBLB CBL | ErbB signaling pathway |
  REAC:R-HSA-195258 | 0.000426856350353 | 0.315789473684 | PAK1 WIPF1 WIPF2 TAX1BP3 WIPF3 WASL | RHO GTPase Effectors |
  GO:0043015 | 0.00126807047383 | 0.210526315789 | PAK1 WIPF3 ARHGEF7 GIT1 | gamma-tubulin binding |
  WP:WP51 | 0.00246235130259 | 0.210526315789 | PAK1 ARHGEF7 ARHGEF6 GIT1 | Regulation of actin cytoskeleton |
  REAC:R-HSA-422475 | 0.00702618619237 | 0.315789473684 | PAK1 WASL GIT1 ARHGEF7 DOK1 NCK2 | Axon guidance |
  REAC:R-HSA-9824443 | 0.00746927717766 | 0.210526315789 | WIPF1 WIPF3 WASL WIPF2 | Parasitic Infection Pathways |
  REAC:R-HSA-9658195 | 0.00746927717766 | 0.210526315789 | WIPF1 WIPF3 WASL WIPF2 | Leishmania infection |
  WP:WP69 | 0.00801036059971 | 0.157894736842 | PAK1 CBLB CBL | T cell receptor signaling pathway |
  REAC:R-HSA-9675108 | 0.00864282892595 | 0.315789473684 | PAK1 WASL GIT1 ARHGEF7 DOK1 NCK2 | Nervous system development |
  HPA:0300000 | 0.010042106516 | 0.894736842105 | CBLB PAK1 SH3PXD2B CASKIN2 NCK2 WIPF2 TAX1BP3 GIT2 WIPF1 GIT1 CBL ARHGEF7 ARHGEF6 DOK1 TNK2 PIK3AP1 WASL | lung |
  REAC:R-HSA-8849469 | 0.0171654763937 | 0.105263157895 | DOK1 CBL | PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 |
  KEGG:04660 | 0.0176633265823 | 0.157894736842 | PAK1 CBLB NCK2 | T cell receptor signaling pathway |
  WP:WP185 | 0.0208105722486 | 0.157894736842 | PAK1 ARHGEF7 GIT2 | Integrin mediated cell adhesion |
  HPA:0600000 | 0.0223875176305 | 0.894736842105 | CBLB PAK1 SH3PXD2B CASKIN2 NCK2 WIPF2 TAX1BP3 GIT2 WIPF1 GIT1 CBL ARHGEF7 ARHGEF6 DOK1 TNK2 PIK3AP1 WASL | tonsil |
  GO:0141124 | 0.031141916262 | 0.526315789474 | PAK1 TAX1BP3 PIK3AP1 GIT2 GIT1 ARHGEF7 ARHGEF6 DOK1 TNK2 CBL | intracellular signaling cassette |
  REAC:R-HSA-428540 | 0.0370766656715 | 0.105263157895 | PAK1 NCK2 | Activation of RAC1 |
  REAC:R-HSA-9013404 | 0.0479847199721 | 0.157894736842 | PAK1 GIT2 GIT1 | RAC2 GTPase cycle |
  CORUM:2513 | 0.0496196263904 | 0.0526315789474 | WASL | N-WASp homomer complex |
  CORUM:5713 | 0.0496196263904 | 0.0526315789474 | CBL | SH3P2/OSTF1-CBL-SRC complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
---|---|---|---|---|
 ARHGEF6 |  GIT1 | 1.0 | 0.218           |
structurally_consistent (dimer)        
|
 ARHGEF7 |  ARHGEF6 | 1.0 |            |
mutually_exclusive (Q9Y2X7)        
|
 NCK2 |  WIPF2 | 1.0 | 0.044           |          |
 GIT2 |  ARHGEF6 | 1.0 | 0.372           |
structurally_consistent (dimer)        
|
 NCK1 |  NCK2 | 1.0 | 0.084           |          |
 ARHGEF6 |  PAK1 | 1.0 | 0.108           |          |
 NCK1 |  WIPF2 | 0.999 | 0.1           |          |
 NCK2 |  WASL | 0.999 | 0.028           |          |
 GIT2 |  ARHGEF7 | 0.999 |            |          |
 ARHGEF7 |  GIT1 | 0.999 |            |
structurally_consistent (dimer)        
|
 ARHGEF7 |  PAK1 | 0.999 |            |          |
 NCK1 |  WASL | 0.999 | 0.126           |          |
 WIPF2 |  WASL | 0.999 | 0.244           |          |
 PIK3AP1 |  NCK2 | 0.998 | 0.06           |          |
 NCK2 |  ARHGEF7 | 0.998 |            |          |
 NCK2 |  TNK2 | 0.998 | 0.07           |          |
 NCK2 |  PAK1 | 0.998 | 0.12           |          |
 WIPF1 |  WASL | 0.997 | 0.13           |          |
 NCK1 |  WIPF1 | 0.997 | 0.052           |          |
 GIT2 |  GIT1 | 0.997 | 0.216           |
mutually_exclusive (Q15052)        
|
 TAX1BP3 |  ARHGEF7 | 0.997 |            |          |
 SH3PXD2B |  NCK2 | 0.997 | 0.03           |          |
 NCK2 |  GIT1 | 0.996 | 0.088           |          |
 NCK2 |  GIT2 | 0.996 | 0.088           |          |
 WIPF3 |  WASL | 0.996 |            |          |
 NCK1 |  PIK3AP1 | 0.994 | 0.056           |          |
 NCK2 |  WIPF1 | 0.994 | 0.04           |          |
 GIT2 |  PAK1 | 0.994 | 0.128           |          |
 WIPF1 |  WIPF2 | 0.993 | 0.16           |          |
 PAK1 |  GIT1 | 0.993 | 0.07           |          |
 NCK2 |  ARHGEF6 | 0.993 | 0.078           |          |
 NCK2 |  WIPF3 | 0.992 |            |          |
 NCK1 |  ARHGEF7 | 0.987 |            |          |
 NCK1 |  TNK2 | 0.984 | 0.204           |          |
 NCK2 |  CASKIN2 | 0.984 | 0.156           |          |
 CBL |  NCK2 | 0.981 | 0.086           |          |
 DOK1 |  NCK2 | 0.979 | 0.062           |          |
 TAX1BP3 |  ARHGEF6 | 0.978 | 0.044           |          |
 PIK3AP1 |  WASL | 0.977 | 0.08           |          |
 NCK1 |  GIT1 | 0.977 | 0.126           |          |
 NCK2 |  CBLB | 0.973 | 0.03           |          |
 PIK3AP1 |  TNK2 | 0.972 | 0.106           |          |
 PIK3AP1 |  WIPF2 | 0.972 | 0.112           |          |
 NCK1 |  PAK1 | 0.972 | 0.236           |          |
 TAX1BP3 |  PAK1 | 0.964 | 0.166           |          |
 TAX1BP3 |  GIT1 | 0.964 | 0.026           |          |
 SH3PXD2B |  CBLB | 0.964 | 0.094           |          |
 WASL |  ARHGEF7 | 0.959 |            |          |
 SHB |  CBL | 0.953 | 0.064           |          |
 SHB |  NCK2 | 0.947 | 0.162           |          |
 TAX1BP3 |  GIT2 | 0.936 | 0.03           |          |
 NCK1 |  GIT2 | 0.935 | 0.176           |          |
 NCK1 |  WIPF3 | 0.933 |            |          |
 WIPF1 |  TNK2 | 0.928 | 0.056           |          |
 WASL |  TNK2 | 0.923 | 0.108           |          |
 NCK1 |  ARHGEF6 | 0.922 | 0.124           |          |
 WIPF2 |  TNK2 | 0.914 | 0.148           |          |
 WIPF2 |  ARHGEF7 | 0.896 |            |          |
 SH3PXD2B |  TNK2 | 0.868 | 0.112           |          |
 NCK1 |  CASKIN2 | 0.862 | 0.0742666666667           |          |
 PIK3AP1 |  ARHGEF7 | 0.855 |            |          |
 CBL |  WIPF2 | 0.849 | 0.104           |          |
 CBL |  NCK1 | 0.84 | 0.046           |          |
 TNK2 |  ARHGEF7 | 0.826 |            |          |
 CBL |  WASL | 0.808 | 0.084           |          |
 TNK2 |  GIT2 | 0.807 | 0.084           |          |
 CBL |  CBLB | 0.805 | 0.408           |          |
 CBL |  PIK3AP1 | 0.797 | 0.11           |          |
 CBL |  WIPF1 | 0.797 | 0.128           |          |
 CBL |  WIPF3 | 0.797 |            |          |
 CBL |  TNK2 | 0.797 | 0.17           |          |
 TNK2 |  GIT1 | 0.786 | 0.06           |          |
 WASL |  GIT2 | 0.786 | 0.088           |          |
 WIPF2 |  WIPF3 | 0.785 |            |          |
 WIPF1 |  WIPF3 | 0.785 |            |          |
 WASL |  GIT1 | 0.779 | 0.17           |          |
 TNK2 |  PAK1 | 0.765 | 0.148           |          |
 TNK2 |  ARHGEF6 | 0.765 | 0.124           |          |
 WASL |  ARHGEF6 | 0.764 | 0.158           |          |
 WIPF2 |  ARHGEF6 | 0.749 | 0.132           |          |
 PIK3AP1 |  ARHGEF6 | 0.725 | 0.15           |          |
 WIPF2 |  GIT1 | 0.724 | 0.24           |          |
 WASL |  PAK1 | 0.723 | 0.168           |          |
 WIPF2 |  GIT2 | 0.704 | 0.168           |          |
 PIK3AP1 |  PAK1 | 0.698 | 0.104           |          |
 PIK3AP1 |  GIT2 | 0.673 | 0.104           |          |
 WIPF2 |  PAK1 | 0.669 | 0.104           |          |
 PIK3AP1 |  GIT1 | 0.663 | 0.062           |          |
 PIK3AP1 |  WIPF3 | 0.622 |            |          |
 PIK3AP1 |  WIPF1 | 0.622 | 0.092           |          |
 WIPF3 |  TNK2 | 0.622 |            |          |
 SH3PXD2B |  WIPF2 | 0.618 | 0.184           |          |
 CBL |  GIT2 | 0.587 | 0.12           |          |
 SH3PXD2B |  PIK3AP1 | 0.559 | 0.038           |          |
 SH3PXD2B |  WASL | 0.544 | 0.144           |          |
 DOK1 |  PIK3AP1 | 0.513 | 0.108           |          |
 DOK1 |  CBLB | 0.513 | 0.078           |          |
 DOK1 |  WIPF2 | 0.513 | 0.104           |          |
 DOK1 |  WIPF1 | 0.513 | 0.182           |          |
 DOK1 |  TNK2 | 0.513 | 0.156           |          |
 DOK1 |  WIPF3 | 0.513 |            |          |
 NCK1 |  SH3PXD2B | 0.501 | 0.07           |          |
 SH3PXD2B |  GIT1 | 0.454 | 0.13           |          |
 CBL |  ARHGEF6 | 0.434 | 0.142           |          |
 SH3PXD2B |  GIT2 | 0.404 | 0.136           |          |
 SH3PXD2B |  ARHGEF7 | 0.404 |            |          |
 DOK1 |  WASL | 0.378 | 0.19           |          |
 SHB |  DOK1 | 0.378 | 0.072           |          |
 DOK1 |  CASKIN2 | 0.377 | 0.076           |          |
 CBL |  CASKIN2 | 0.369 | 0.066           |          |
 CASKIN2 |  WASL | 0.353 | 0.18           |          |
 CASKIN2 |  WIPF3 | 0.353 |            |          |
 PIK3AP1 |  CASKIN2 | 0.353 | 0.08           |          |
 CASKIN2 |  WIPF2 | 0.353 | 0.16           |          |
 CASKIN2 |  TNK2 | 0.353 | 0.106           |          |
 CASKIN2 |  WIPF1 | 0.353 | 0.09           |          |
 DOK1 |  NCK1 | 0.339 | 0.096           |          |
 SH3PXD2B |  ARHGEF6 | 0.326 | 0.224           |          |
 WIPF3 |  ARHGEF7 | 0.324 |            |          |
 WIPF1 |  GIT2 | 0.324 | 0.274           |          |
 WIPF1 |  ARHGEF7 | 0.324 |            |          |
 WIPF3 |  GIT2 | 0.324 |            |          |
 SH3PXD2B |  PAK1 | 0.321 | 0.11           |          |
 WIPF3 |  GIT1 | 0.315 |            |          |
 WIPF1 |  GIT1 | 0.315 | 0.114           |          |
 WIPF3 |  ARHGEF6 | 0.3 |            |          |
 WIPF1 |  ARHGEF6 | 0.3 | 0.194           |          |
 CASKIN2 |  PAK1 | 0.297 | 0.144           |          |
 CASKIN2 |  ARHGEF7 | 0.293 |            |          |
 CASKIN2 |  GIT2 | 0.293 | 0.084           |          |
 CBLB |  WASL | 0.291 | 0.12           |          |
 CBLB |  WIPF2 | 0.291 | 0.064           |          |
 CBLB |  TNK2 | 0.291 | 0.142           |          |
 CBLB |  WIPF1 | 0.291 | 0.076           |          |
 CBLB |  WIPF3 | 0.291 |            |          |
 PIK3AP1 |  CBLB | 0.291 | 0.116           |          |
 CASKIN2 |  GIT1 | 0.285 | 0.154           |          |
 WIPF1 |  PAK1 | 0.275 | 0.11           |          |
 WIPF3 |  PAK1 | 0.275 |            |          |
 SH3PXD2B |  CASKIN2 | 0.247 | 0.088           |          |
 SH3PXD2B |  WIPF1 | 0.247 | 0.068           |          |
 SH3PXD2B |  WIPF3 | 0.247 |            |          |
 CBLB |  ARHGEF7 | 0.242 |            |          |
 CBLB |  GIT1 | 0.242 | 0.108           |          |
 SHB |  NCK1 | 0.242 | 0.14           |          |
 CBLB |  GIT2 | 0.242 | 0.106           |          |
 CBL |  SH3PXD2B | 0.238 | 0.05           |          |
 SHB |  ARHGEF6 | 0.233 | 0.096           |          |
 SHB |  GIT2 | 0.233 | 0.1           |          |
 SHB |  ARHGEF7 | 0.233 |            |          |
 SHB |  GIT1 | 0.233 | 0.094           |          |
 CASKIN2 |  ARHGEF6 | 0.233 | 0.196           |          |
 SHB |  PAK1 | 0.225 | 0.166           |          |
 SHB |  CBLB | 0.224 | 0.068           |          |
 SHB |  TNK2 | 0.224 | 0.08           |          |
 SHB |  WIPF1 | 0.224 | 0.104           |          |
 SHB |  PIK3AP1 | 0.224 | 0.028           |          |
 CBL |  DOK1 | 0.224 | 0.126           |          |
 SHB |  WIPF3 | 0.224 |            |          |
 CBLB |  PAK1 | 0.22 | 0.226           |          |
 CBLB |  ARHGEF6 | 0.216 | 0.174           |          |
 SHB |  WIPF2 | 0.215 | 0.128           |          |
 CASKIN2 |  CBLB | 0.215 | 0.078           |          |
 DOK1 |  SH3PXD2B | 0.215 | 0.07           |          |
 SHB |  CASKIN2 | 0.215 | 0.088           |          |
 SHB |  SH3PXD2B | 0.215 | 0.146           |          |
 SHB |  WASL | 0.215 | 0.184           |          |
 DOK1 |  ARHGEF6 | 0.188 | 0.13           |          |
 NCK1 |  CBLB | 0.188 | 0.07           |          |
 DOK1 |  GIT1 | 0.188 | 0.124           |          |
 DOK1 |  ARHGEF7 | 0.188 |            |          |
 DOK1 |  GIT2 | 0.188 | 0.102           |          |
 DOK1 |  PAK1 | 0.17 | 0.118           |          |
 CBL |  GIT1 | 0.169 | 0.146           |          |
 CBL |  ARHGEF7 | 0.167 |            |          |
 CBL |  PAK1 | 0.156 | 0.186           |          |
 CASKIN2 |  TAX1BP3 | 0.101 | 0.076           |          |
 CBLB |  TAX1BP3 | 0.042 | 0.134           |          |
 SH3PXD2B |  TAX1BP3 | 0.012 | 0.052           |          |
Related Complexes