hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14934.1

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
ARFGAP1	ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)	5	UniProt NCBI
GSTM1	Glutathione S-transferase Mu 1 (EC 2.5.1.18) (GST HB subunit 4) (GST class-mu 1) (GSTM1-1) (GSTM1a-1a) (GSTM1b-1b) (GTH4)	5	UniProt NCBI
GSTM2	Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST class-mu 2) (GSTM2-2)	5	UniProt NCBI
GSTM3	Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3) (hGSTM3-3)	5	UniProt NCBI
GSTM4	Glutathione S-transferase Mu 4 (EC 2.5.1.18) (GST class-mu 4) (GST-Mu2) (GSTM4-4) (Leukotriene C4 synthase GSTM4) (EC 4.4.1.20)	5	UniProt NCBI
GSTM5	Glutathione S-transferase Mu 5 (EC 2.5.1.18) (GST class-mu 5) (GSTM5-5)	5	UniProt NCBI
PPP1R13B	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)	5	UniProt NCBI
RASSF9	Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor)	4	UniProt NCBI
UCP1	Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Solute carrier family 25 member 7) (Thermogenin)	5	UniProt NCBI

Showing 1 to 9 of 9 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-156590	4.30104656022e-10	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Glutathione conjugation
KEGG:00480	1.04967378663e-09	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Glutathione metabolism
KEGG:05204	1.42096473e-09	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Chemical carcinogenesis - DNA adducts
KEGG:00982	1.56569247718e-09	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Drug metabolism - cytochrome P450
KEGG:00980	2.47643117257e-09	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Metabolism of xenobiotics by cytochrome P450
KEGG:00983	4.77064270497e-09	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Drug metabolism - other enzymes
KEGG:01524	5.97551490727e-09	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Platinum drug resistance
GO:0004364	1.32402198725e-08	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	glutathione transferase activity
REAC:R-HSA-156580	5.09241824227e-08	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Phase II - Conjugation of compounds
KEGG:05418	8.20570400711e-08	0.625	GSTM4 GSTM3 GSTM5 GSTM2 GSTM1	Fluid shear stress and atherosclerosis

Showing 1 to 10 of 43 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
GSTM4	GSTM2	1.0	0.114	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM3	GSTM2	1.0	0.516	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM4	GSTM3	0.999	0.172	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM5	GSTM2	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM5	GSTM3	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM4	GSTM5	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM5	ARFGAP1	0.995		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
PPP1R13B	GSTM3	0.991	0.046	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GSTM1	GSTM2	0.984	0.108	bioplex3_WMM bioplex3_HCT116 WMM_only
GSTM1	GSTM5	0.972		bioplex3_WMM bioplex3_HCT116 WMM_only

Showing 1 to 10 of 21 entries

Related Complexes

Genename	Complexes
GSTM4	huMAP3_01673.1 huMAP3_14934.1
PPP1R13B	huMAP3_00020.1 huMAP3_06304.1 huMAP3_06341.1 huMAP3_08482.1 huMAP3_08717.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09755.1 huMAP3_10148.1 huMAP3_10901.1 huMAP3_14504.1 huMAP3_14934.1
UCP1	huMAP3_13858.1 huMAP3_14934.1
ARFGAP1	huMAP3_05105.1 huMAP3_05120.1 huMAP3_05849.1 huMAP3_08320.1 huMAP3_09403.1 huMAP3_10876.1 huMAP3_14934.1
GSTM1	huMAP3_01673.1 huMAP3_13858.1 huMAP3_14934.1
GSTM5	huMAP3_01673.1 huMAP3_14445.1 huMAP3_14656.1 huMAP3_14934.1
RASSF9	huMAP3_14504.1 huMAP3_14934.1
GSTM3	huMAP3_01673.1 huMAP3_14934.1
GSTM2	huMAP3_01673.1 huMAP3_14934.1