hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14937.1
Complex Portal: CPX-12801
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TNS3 | Tensin-3 (EC 3.1.3.-) (Tensin-like SH2 domain-containing protein 1) (Tumor endothelial marker 6) | 5 | UniProt NCBI |
| TNRC6C | Trinucleotide repeat-containing gene 6C protein | 5 | UniProt NCBI |
| DEF6 | Differentially expressed in FDCP 6 homolog (DEF-6) (IRF4-binding protein) | 5 | UniProt NCBI |
| PRKCQ | Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta) | 5 | UniProt NCBI |
| CECR2 | Chromatin remodeling regulator CECR2 (Cat eye syndrome critical region protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8936459 | 0.0475253950332 | 0.4 | TNRC6C PRKCQ | RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function |
| CORUM:917 | 0.0498708842806 | 0.2 | CECR2 | CERF complex (CECR2-containing remodeling factor complex) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TNS3 | DEF6 | 0.996 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DEF6 | CECR2 | 0.991 | 0.064 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TNRC6C | DEF6 | 0.976 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| DEF6 | PRKCQ | 0.821 | 0.13 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM treiber_WMM | |
| TNS3 | PRKCQ | 0.572 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| TNS3 | CECR2 | 0.557 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| CECR2 | PRKCQ | 0.378 | 0.124 | bioplex_WMM bioplex3_WMM WMM_only | |
| TNRC6C | TNS3 | 0.29 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only | |
| TNRC6C | CECR2 | 0.185 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| TNRC6C | PRKCQ | 0.075 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes