hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14966.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CYP3A5 | Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3) | 5 | UniProt NCBI |
| CYSTM1 | Cysteine-rich and transmembrane domain-containing protein 1 | 3 | UniProt NCBI |
| CYP3A4 | Cytochrome P450 3A4 (EC 1.14.14.1) (1,4-cineole 2-exo-monooxygenase) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55) | 5 | UniProt NCBI |
| CYP3A7 | Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA) (P450HLp2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2536 | 0.00622025938483 | 0.5 | CYP3A4 | Colchicine metabolic pathway |
| WP:WP2646 | 0.0124400931326 | 0.5 | CYP3A4 | Lidocaine metabolism |
| WP:WP2816 | 0.0124400931326 | 0.5 | CYP3A4 | Felbamate metabolism |
| WP:WP4174 | 0.0124400931326 | 0.5 | CYP3A4 | Metabolism of tetrahydrocannabinol THC |
| WP:WP2826 | 0.0248784837172 | 0.5 | CYP3A4 | Cocaine metabolism |
| WP:WP699 | 0.0435328773163 | 0.5 | CYP3A4 | Aflatoxin B1 metabolism |
| WP:WP2874 | 0.049750157242 | 0.5 | CYP3A4 | Liver X receptor pathway |
| WP:WP696 | 0.049750157242 | 0.5 | CYP3A4 | Benzo a pyrene metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CYP3A5 | CYP3A7 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CYP3A5 | CYP3A4 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CYSTM1 | CYP3A7 | 0.85 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CYP3A5 | CYSTM1 | 0.274 | bioplex3_WMM WMM_only | |
| CYP3A4 | CYP3A7 | 0.214 | bioplex3_WMM WMM_only |
Related Complexes