hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14973.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LTA4H | Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) (Tripeptide aminopeptidase LTA4H) (EC 3.4.11.4) | 5 | UniProt NCBI |
| GRHPR | Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81) | 5 | UniProt NCBI |
| PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | 5 | UniProt NCBI |
| PKM | Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58) | 5 | UniProt NCBI |
| ANP32B | Acidic leucine-rich nuclear phosphoprotein 32 family member B (Acidic protein rich in leucines) (Putative HLA-DR-associated protein I-2) (PHAPI2) (Silver-stainable protein SSP29) | 5 | UniProt NCBI |
| SIGLEC5 | Sialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3183 | 0.0498708842806 | 0.2 | PTPN11 | PDGFRA-SHP-2 complex, PDGF stimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PTPN11 | SIGLEC5 | 0.933 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PTPN11 | ANP32B | 0.927 | 0.176 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| PTPN11 | PKM | 0.913 | 0.372 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM fraction |
| PTPN11 | GRHPR | 0.844 | 0.088 | bioplex_WMM bioplex3_WMM fraction |
| PTPN11 | LTA4H | 0.812 | 0.206 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| ANP32B | LTA4H | 0.288 | 0.15 | bioplex_WMM bioplex3_WMM WMM_only |
| PKM | LTA4H | 0.074 | 0.476 | bioplex_WMM bioplex3_WMM fraction treiber_WMM |
| ANP32B | GRHPR | 0.045 | 0.214 | bioplex_WMM bioplex3_WMM WMM_only |
| GRHPR | PKM | 0.036 | 0.296 | bioplex_WMM bioplex3_WMM fraction treiber_WMM |
| GRHPR | LTA4H | 0.03 | 0.218 | bioplex_WMM bioplex3_WMM fraction |
| PKM | SIGLEC5 | 0.005 | bioplex3_HEK293 bioplex () | |
| ANP32B | PKM | 0.003 | 0.378 | bioplex_WMM bioplex3_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes