hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14975.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PIGL | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L) | 5 | UniProt NCBI |
| PAQR7 | Membrane progestin receptor alpha (mPR alpha) (Membrane progesterone P4 receptor alpha) (Membrane progesterone receptor alpha) (Progesterone and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member VII) | 4 | UniProt NCBI |
| CALCRL | Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor) | 5 | UniProt NCBI |
| SMIM20 | Small integral membrane protein 20 (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa) (MITRAC7) [Cleaved into: Phoenixin-14 (PNX-14); Phoenixin-20 (PNX-20)] | 5 | UniProt NCBI |
| LPAR2 | Lysophosphatidic acid receptor 2 (LPA receptor 2) (LPA-2) (Lysophosphatidic acid receptor Edg-4) | 5 | UniProt NCBI |
| RAMP1 | Receptor activity-modifying protein 1 (Calcitonin-receptor-like receptor activity-modifying protein 1) (CRLR activity-modifying protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1300 | 1.70876175213e-05 | 0.333333333333 | CALCRL RAMP1 | CRLR-RAMP1 complex |
| CORUM:1301 | 1.70876175213e-05 | 0.333333333333 | CALCRL RAMP1 | CRLR-RAMP1 complex |
| REAC:R-HSA-419812 | 0.000541723162524 | 0.333333333333 | CALCRL RAMP1 | Calcitonin-like ligand receptors |
| WP:WP2197 | 0.0023190863075 | 0.333333333333 | CALCRL RAMP1 | Endothelin pathways |
| GO:0001635 | 0.00702301080125 | 0.333333333333 | CALCRL RAMP1 | calcitonin gene-related peptide receptor activity |
| GO:1990406 | 0.00702301080125 | 0.333333333333 | CALCRL RAMP1 | CGRP receptor complex |
| REAC:R-HSA-500792 | 0.0134812218215 | 0.5 | CALCRL LPAR2 RAMP1 | GPCR ligand binding |
| GO:0097644 | 0.0210651876021 | 0.333333333333 | CALCRL RAMP1 | calcitonin family binding |
| GO:1990408 | 0.0210651876021 | 0.333333333333 | CALCRL RAMP1 | calcitonin gene-related peptide receptor signaling pathway |
| KEGG:04270 | 0.0325874784997 | 0.333333333333 | CALCRL RAMP1 | Vascular smooth muscle contraction |
| GO:0097642 | 0.042122686785 | 0.333333333333 | CALCRL RAMP1 | calcitonin family receptor activity |
| GO:1903439 | 0.042122686785 | 0.333333333333 | CALCRL RAMP1 | calcitonin family receptor complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PIGL | LPAR2 | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CALCRL | RAMP1 | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| LPAR2 | PAQR7 | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SMIM20 | CALCRL | 0.902 | bioplex3_WMM WMM_only | |
| SMIM20 | PIGL | 0.902 | bioplex3_WMM WMM_only | |
| PIGL | CALCRL | 0.902 | bioplex3_WMM WMM_only | |
| PIGL | PAQR7 | 0.722 | bioplex3_WMM WMM_only |
Related Complexes