hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14989.1
Complex Portal: CPX-18761
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATG2B | Autophagy-related protein 2 homolog B | 5 | UniProt NCBI |
| WDR45 | WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45) | 5 | UniProt NCBI |
| UBTD1 | Ubiquitin domain-containing protein 1 | 5 | UniProt NCBI |
| ATG2A | Autophagy-related protein 2 homolog A | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04140 | 0.000211376960202 | 0.75 | ATG2B ATG2A WDR45 | Autophagy - animal |
| GO:0044804 | 0.000261258639543 | 0.75 | ATG2B ATG2A WDR45 | nucleophagy |
| KEGG:04136 | 0.00108828934266 | 0.5 | ATG2B ATG2A | Autophagy - other |
| GO:0000407 | 0.00190418300832 | 0.75 | ATG2B ATG2A WDR45 | phagophore assembly site |
| WP:WP4577 | 0.00198508114189 | 0.5 | WDR45 ATG2A | Neurodegeneration with brain iron accumulation NBIA subtypes pathway |
| GO:0032266 | 0.0025122894873 | 0.75 | ATG2B ATG2A WDR45 | phosphatidylinositol-3-phosphate binding |
| KEGG:05017 | 0.0192212154966 | 0.5 | ATG2B ATG2A | Spinocerebellar ataxia |
| GO:0000422 | 0.0302857026499 | 0.75 | ATG2B ATG2A WDR45 | autophagy of mitochondrion |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| WDR45 | ATG2B | 0.994 | 0.15 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| ATG2A | WDR45 | 0.991 | 0.12 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_WMM hein () |
| ATG2A | UBTD1 | 0.974 | 0.066 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| WDR45 | UBTD1 | 0.408 | 0.09 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes