hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14993.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHST6 | Carbohydrate sulfotransferase 6 (Corneal N-acetylglucosamine-6-O-sulfotransferase) (C-GlcNAc6ST) (hCGn6ST) (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta) (GST4-beta) (N-acetylglucosamine 6-O-sulfotransferase 5) (GlcNAc6ST-5) (Gn6st-5) | 5 | UniProt NCBI |
| CHST4 | Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2) | 5 | UniProt NCBI |
| CHST5 | Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha) (GST4-alpha) (Intestinal N-acetylglucosamine-6-O-sulfotransferase) (I-GlcNAc6ST) (Intestinal GlcNAc-6-sulfotransferase) (hIGn6ST) (N-acetylglucosamine 6-O-sulfotransferase 3) (GlcNAc6ST-3) (Gn6st-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0001517 | 9.61200410764e-07 | 1.0 | CHST6 CHST5 CHST4 | N-acetylglucosamine 6-O-sulfotransferase activity |
| GO:0006044 | 2.74903317479e-05 | 1.0 | CHST6 CHST5 CHST4 | N-acetylglucosamine metabolic process |
| WP:WP702 | 3.10835934447e-05 | 1.0 | CHST6 CHST5 CHST4 | Metapathway biotransformation Phase I and II |
| KEGG:00533 | 5.03594835644e-05 | 0.666666666667 | CHST6 CHST4 | Glycosaminoglycan biosynthesis - keratan sulfate |
| GO:1901071 | 0.000109576846827 | 1.0 | CHST6 CHST5 CHST4 | glucosamine-containing compound metabolic process |
| GO:0006040 | 0.000575182325801 | 1.0 | CHST6 CHST5 CHST4 | amino sugar metabolic process |
| GO:0008146 | 0.000949666005835 | 1.0 | CHST6 CHST5 CHST4 | sulfotransferase activity |
| REAC:R-HSA-2022854 | 0.00188000535098 | 0.666666666667 | CHST6 CHST5 | Keratan sulfate biosynthesis |
| GO:0016782 | 0.00252170927764 | 1.0 | CHST6 CHST5 CHST4 | transferase activity, transferring sulphur-containing groups |
| REAC:R-HSA-1638074 | 0.00296224002415 | 0.666666666667 | CHST6 CHST5 | Keratan sulfate/keratin metabolism |
| GO:0006477 | 0.0140440992017 | 0.666666666667 | CHST4 CHST5 | protein sulfation |
| REAC:R-HSA-1630316 | 0.0406752460979 | 0.666666666667 | CHST6 CHST5 | Glycosaminoglycan metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CHST6 | CHST4 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CHST6 | CHST5 | 0.992 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CHST6 | huMAP3_04123.1 huMAP3_05681.1 huMAP3_14993.1 |
| CHST4 | huMAP3_04123.1 huMAP3_05681.1 huMAP3_14993.1 |
| CHST5 | huMAP3_04123.1 huMAP3_05681.1 huMAP3_11778.1 huMAP3_12446.1 huMAP3_14993.1 |