hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14996.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KIT | Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) | 5 | UniProt NCBI |
| IFNB1 | Interferon beta (IFN-beta) (Fibroblast interferon) | 5 | UniProt NCBI |
| EDAR | Tumor necrosis factor receptor superfamily member EDAR (Anhidrotic ectodysplasin receptor 1) (Downless homolog) (EDA-A1 receptor) (Ectodermal dysplasia receptor) (Ectodysplasin-A receptor) | 5 | UniProt NCBI |
| MOSPD1 | Motile sperm domain-containing protein 1 | 4 | UniProt NCBI |
| IFNAR1 | Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04060 | 0.0146065267115 | 0.666666666667 | IFNB1 EDAR | Cytokine-cytokine receptor interaction |
| CORUM:552 | 0.0499402709677 | 0.333333333333 | IFNB1 | IFNAR1-IFNAR2-IFNB1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IFNAR1 | IFNB1 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| EDAR | KIT | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| EDAR | MOSPD1 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| EDAR | IFNAR1 | 0.931 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| KIT | IFNAR1 | 0.886 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MOSPD1 | IFNAR1 | 0.415 | bioplex3_WMM WMM_only | |
| KIT | MOSPD1 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes