hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15006.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C6orf136 | Uncharacterized protein C6orf136 | 2 | UniProt NCBI |
| WRN | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)] | 5 | UniProt NCBI |
| SLC35A3 | UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter) (Solute carrier family 35 member A3) | 5 | UniProt NCBI |
| PAXX | Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:4082 | 0.0249718442456 | 0.25 | WRN | XRCC6-XRCC5-WRN complex |
| CORUM:6619 | 0.0249718442456 | 0.25 | SLC35A3 | MGAT1-NGT complex |
| CORUM:1217 | 0.049938562206 | 0.25 | WRN | WRN-TRF2 complex |
| CORUM:5235 | 0.049938562206 | 0.25 | WRN | WRN-Ku70-Ku80-PARP1 complex |
| CORUM:6622 | 0.049938562206 | 0.25 | SLC35A3 | MGAT2-SLC35A3 complex |
| CORUM:6624 | 0.049938562206 | 0.25 | SLC35A3 | MGAT4B-SLC35A3 complex |
| CORUM:6629 | 0.049938562206 | 0.25 | SLC35A3 | MAGT5-SLC35A3 complex |
| CORUM:7282 | 0.049938562206 | 0.25 | WRN | FEN1-WRN complex |
| REAC:R-HSA-5619083 | 0.0499436884912 | 0.25 | SLC35A3 | Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| WRN | PAXX | 0.981 | 0.068 | hein_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
| C6orf136 | PAXX | 0.968 | 0.028 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PAXX | SLC35A3 | 0.925 | 0.07 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes