hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15042.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SARM1 | NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR) | 5 | UniProt NCBI |
| OIP5 | Protein Mis18-beta (Cancer/testis antigen 86) (CT86) (Opa-interacting protein 5) (OIP-5) | 5 | UniProt NCBI |
| CAV3 | Caveolin-3 (M-caveolin) | 5 | UniProt NCBI |
| MIS18BP1 | Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243) | 5 | UniProt NCBI |
| CENPA | Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A) | 5 | UniProt NCBI |
| MIS18A | Protein Mis18-alpha (FAPP1-associated protein 1) | 5 | UniProt NCBI |
| CCDC170 | Coiled-coil domain-containing protein 170 | 5 | UniProt NCBI |
| G0S2 | G0/G1 switch protein 2 (G0/G1 switch regulatory protein 2) (Putative lymphocyte G0/G1 switch gene) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6434 | 7.02338504734e-09 | 0.428571428571 | OIP5 MIS18A MIS18BP1 | MIS18 complex |
| REAC:R-HSA-606279 | 1.84539860471e-06 | 0.571428571429 | OIP5 CENPA MIS18A MIS18BP1 | Deposition of new CENPA-containing nucleosomes at the centromere |
| REAC:R-HSA-774815 | 1.84539860471e-06 | 0.571428571429 | OIP5 CENPA MIS18A MIS18BP1 | Nucleosome assembly |
| REAC:R-HSA-73886 | 3.61497405074e-05 | 0.571428571429 | OIP5 CENPA MIS18A MIS18BP1 | Chromosome Maintenance |
| GO:0031055 | 0.000117650375223 | 0.428571428571 | OIP5 MIS18A CENPA | chromatin remodeling at centromere |
| GO:0034080 | 0.000117650375223 | 0.428571428571 | OIP5 MIS18A CENPA | CENP-A containing chromatin assembly |
| GO:0034508 | 0.00445787546995 | 0.428571428571 | OIP5 MIS18A CENPA | centromere complex assembly |
| REAC:R-HSA-1640170 | 0.0231929958906 | 0.571428571429 | OIP5 CENPA MIS18A MIS18BP1 | Cell Cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MIS18A | OIP5 | 1.0 | 0.292 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| MIS18BP1 | MIS18A | 1.0 | 0.282 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| MIS18BP1 | OIP5 | 0.999 | 0.194 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| SARM1 | CAV3 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MIS18BP1 | CAV3 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MIS18A | CCDC170 | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| OIP5 | G0S2 | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CAV3 | OIP5 | 0.926 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CENPA | OIP5 | 0.926 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CENPA | MIS18A | 0.922 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| MIS18A | G0S2 | 0.847 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CAV3 | MIS18A | 0.844 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MIS18BP1 | CCDC170 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | |
| SARM1 | OIP5 | 0.161 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only |
| SARM1 | MIS18BP1 | 0.1 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only |
| SARM1 | MIS18A | 0.095 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only |
| OIP5 | CCDC170 | 0.047 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes