hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15051.1
Complex Portal: CPX-20771
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DHRSX | Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY) (Short chain dehydrogenase/reductase family 46C member 1) (Short chain dehydrogenase/reductase family 7C member 6) | 5 | UniProt NCBI |
| ZBED1 | E3 SUMO-protein ligase ZBED1 (EC 2.3.2.-) (DNA replication-related element-binding factor) (Putative Ac-like transposable element) (Zinc finger BED domain-containing protein 1) (dREF homolog) | 5 | UniProt NCBI |
| HARS1 | Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) | 5 | UniProt NCBI |
| CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05033 | 0.0385480863284 | 1.0 | CHRNA7 | Nicotine addiction |
| WP:WP4942 | 0.0454335014827 | 1.0 | CHRNA7 | 15q13 3 copy number variation syndrome |
| CORUM:7239 | 0.0499436884912 | 1.0 | CHRNA7 | CHRNA7-NMDAR1 complex |
| CORUM:7240 | 0.0499436884912 | 1.0 | CHRNA7 | CHRNA7-GRIN2A complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DHRSX | ZBED1 | 0.999 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CHRNA7 | DHRSX | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CHRNA7 | HARS1 | 0.831 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HARS1 | DHRSX | 0.12 | 0.052 | bioplex3_WMM WMM_only |
Related Complexes