hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15054.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MICALL1 | MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13) | 5 | UniProt NCBI |
| ASAP1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) | 5 | UniProt NCBI |
| SYNJ2 | Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2) | 5 | UniProt NCBI |
| ASAP3 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1) | 5 | UniProt NCBI |
| SH3D19 | SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP) | 5 | UniProt NCBI |
| RTKN2 | Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1) | 5 | UniProt NCBI |
| ARAP1 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2) | 5 | UniProt NCBI |
| SH3KBP1 | SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.000200506538606 | 0.5 | ASAP1 SH3KBP1 ARAP1 ASAP3 | Endocytosis |
| CORUM:3173 | 0.0499436884912 | 0.125 | SH3KBP1 | CIN85 homotetramer complex |
| CORUM:3174 | 0.0499436884912 | 0.125 | SH3KBP1 | CIN85-BLNK complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RTKN2 | SH3KBP1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SH3KBP1 | MICALL1 | 0.999 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| ARAP1 | SH3KBP1 | 0.999 | 0.068 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SH3KBP1 | ASAP1 | 0.998 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| SH3D19 | SH3KBP1 | 0.996 | 0.102 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
| SH3D19 | ARAP1 | 0.983 | 0.142 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| ASAP1 | ASAP3 | 0.965 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SYNJ2 | SH3KBP1 | 0.954 | 0.064 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| ARAP1 | ASAP1 | 0.942 | 0.414 | bioplex_WMM bioplex3_WMM WMM_only |
| RTKN2 | ASAP1 | 0.908 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RTKN2 | MICALL1 | 0.869 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARAP1 | RTKN2 | 0.852 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARAP1 | MICALL1 | 0.73 | 0.018 | bioplex_WMM bioplex3_WMM WMM_only |
| MICALL1 | ASAP1 | 0.391 | 0.034 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| SYNJ2 | RTKN2 | 0.362 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SH3D19 | RTKN2 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | |
| SYNJ2 | MICALL1 | 0.281 | 0.068 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| SH3D19 | SYNJ2 | 0.252 | 0.076 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| ARAP1 | SYNJ2 | 0.164 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only |
| SH3D19 | MICALL1 | 0.1 | 0.054 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| SH3D19 | ASAP1 | 0.096 | 0.086 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| ARAP1 | ASAP3 | 0.076 | 0.084 | bioplex3_WMM WMM_only |
| SYNJ2 | ASAP1 | 0.068 | 0.150465753425 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes