hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15055.1
Complex Portal: CPX-18302
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MIS18A | Protein Mis18-alpha (FAPP1-associated protein 1) | 5 | UniProt NCBI |
| CENPA | Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A) | 5 | UniProt NCBI |
| CCDC170 | Coiled-coil domain-containing protein 170 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-606279 | 0.01244419045 | 0.666666666667 | CENPA MIS18A | Deposition of new CENPA-containing nucleosomes at the centromere |
| REAC:R-HSA-774815 | 0.01244419045 | 0.666666666667 | CENPA MIS18A | Nucleosome assembly |
| GO:0031055 | 0.0294899169624 | 0.666666666667 | CENPA MIS18A | chromatin remodeling at centromere |
| GO:0034080 | 0.0294899169624 | 0.666666666667 | CENPA MIS18A | CENP-A containing chromatin assembly |
| CORUM:7413 | 0.0499402709677 | 0.333333333333 | CENPA | CENP-A-histone H4 heterodimer- HJURP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MIS18A | CCDC170 | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CENPA | MIS18A | 0.922 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| MIS18A | huMAP3_04715.1 huMAP3_14811.1 huMAP3_15038.1 huMAP3_15042.1 huMAP3_15055.1 |
| CENPA | huMAP3_00090.1 huMAP3_14811.1 huMAP3_15038.1 huMAP3_15042.1 huMAP3_15055.1 |
| CCDC170 | huMAP3_04715.1 huMAP3_14811.1 huMAP3_15038.1 huMAP3_15042.1 huMAP3_15055.1 |