hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_15065.1

Complex Portal: CPX-14943

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
RXRB	Retinoic acid receptor RXR-beta (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta)	5	UniProt NCBI
ZNF784	Zinc finger protein 784	4	UniProt NCBI
FLYWCH2	FLYWCH family member 2	2	UniProt NCBI
PPARG	Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP170	0.00096305612306	0.5	RXRB PPARG	Nuclear receptors
KEGG:05216	0.0014030052018	0.5	RXRB PPARG	Thyroid cancer
WP:WP3942	0.0035028118218	0.5	RXRB PPARG	PPAR signaling pathway
KEGG:03320	0.00426927356048	0.5	RXRB PPARG	PPAR signaling pathway
REAC:R-HSA-383280	0.00507136546841	0.5	RXRB PPARG	Nuclear Receptor transcription pathway
CORUM:5367	0.0249718442456	0.25	RXRB	THRB-RXRB complex
KEGG:05202	0.0295193078423	0.5	RXRB PPARG	Transcriptional misregulation in cancer
KEGG:05417	0.0397541089323	0.5	RXRB PPARG	Lipid and atherosclerosis
REAC:R-HSA-1989781	0.0492961191682	0.5	RXRB PPARG	PPARA activates gene expression

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ZNF784	FLYWCH2	0.975			bioplex3_WMM bioplex3_HCT116 WMM_only
FLYWCH2	PPARG	0.937			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
RXRB	FLYWCH2	0.859	0.02		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM

Related Complexes

Genename	Complexes
RXRB	huMAP3_00358.1 huMAP3_04754.1 huMAP3_08772.1 huMAP3_10891.1 huMAP3_12296.1 huMAP3_13551.1 huMAP3_15065.1
ZNF784	huMAP3_04403.1 huMAP3_08185.1 huMAP3_11542.1 huMAP3_12485.1 huMAP3_13246.1 huMAP3_14452.1 huMAP3_15065.1
FLYWCH2	huMAP3_04403.1 huMAP3_13246.1 huMAP3_14065.1 huMAP3_15065.1
PPARG	huMAP3_13246.1 huMAP3_14065.1 huMAP3_15065.1