hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15075.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CR2 | Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21) | 5 | UniProt NCBI |
| GRAMD2A | GRAM domain-containing protein 2A | 5 | UniProt NCBI |
| NECTIN1 | Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) | 5 | UniProt NCBI |
| ITGA1 | Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a) | 5 | UniProt NCBI |
| JAG1 | Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339) | 5 | UniProt NCBI |
| ACE | Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] | 5 | UniProt NCBI |
| MEGF9 | Multiple epidermal growth factor-like domains protein 9 (Multiple EGF-like domains protein 9) (Epidermal growth factor-like protein 5) (EGF-like protein 5) | 4 | UniProt NCBI |
| EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3413 | 0.00105547828549 | 0.333333333333 | ITGA1 JAG1 | NOTCH1 regulation of endothelial cell calcification |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NECTIN1 | ITGA1 | 0.955 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only |
| ACE | MEGF9 | 0.946 | 0.078 | bioplex3_WMM WMM_only |
| MEGF9 | EFCAB14 | 0.946 | 0.064 | bioplex3_WMM WMM_only |
| ACE | EFCAB14 | 0.946 | 0.07 | bioplex3_WMM WMM_only |
| ACE | ITGA1 | 0.923 | 0.14 | bioplex3_WMM WMM_only |
| EFCAB14 | ITGA1 | 0.923 | 0.106583333333 | bioplex3_WMM WMM_only |
| ACE | NECTIN1 | 0.902 | 0.13 | bioplex3_WMM WMM_only |
| CR2 | NECTIN1 | 0.902 | bioplex3_WMM WMM_only | |
| MEGF9 | NECTIN1 | 0.902 | 0.064 | bioplex3_WMM WMM_only |
| CR2 | MEGF9 | 0.902 | bioplex3_WMM WMM_only | |
| CR2 | ACE | 0.902 | 0.106 | bioplex3_WMM WMM_only |
| CR2 | ITGA1 | 0.902 | 0.141583333333 | bioplex3_WMM WMM_only |
| CR2 | JAG1 | 0.902 | bioplex3_WMM WMM_only | |
| MEGF9 | JAG1 | 0.902 | 0.146 | bioplex3_WMM WMM_only |
| CR2 | EFCAB14 | 0.902 | bioplex3_WMM WMM_only | |
| EFCAB14 | GRAMD2A | 0.902 | bioplex3_WMM WMM_only | |
| EFCAB14 | NECTIN1 | 0.902 | 0.054 | bioplex3_WMM WMM_only |
| NECTIN1 | JAG1 | 0.902 | 0.092 | bioplex3_WMM WMM_only |
| ACE | JAG1 | 0.902 | 0.198 | bioplex3_WMM WMM_only |
| MEGF9 | ITGA1 | 0.827 | 0.118 | bioplex3_WMM WMM_only |
| EFCAB14 | JAG1 | 0.717 | 0.14 | bioplex3_WMM WMM_only |
| ITGA1 | JAG1 | 0.656 | 0.246 | bioplex3_WMM WMM_only |
Related Complexes