hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15119.1
Complex Portal: CPX-21699
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PIWIL1 | Piwi-like protein 1 (EC 3.1.26.-) | 5 | UniProt NCBI |
| PIWIL4 | Piwi-like protein 4 | 5 | UniProt NCBI |
| TDRKH | Tudor and KH domain-containing protein (Tudor domain-containing protein 2) | 5 | UniProt NCBI |
| ARHGAP19 | Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5601884 | 2.4825378684e-06 | 0.75 | PIWIL1 TDRKH PIWIL4 | PIWI-interacting RNA (piRNA) biogenesis |
| GO:0034587 | 0.000139871762976 | 0.75 | PIWIL1 TDRKH PIWIL4 | piRNA processing |
| GO:0043186 | 0.000261258639543 | 0.75 | PIWIL1 TDRKH PIWIL4 | P granule |
| GO:0045495 | 0.000261258639543 | 0.75 | PIWIL1 TDRKH PIWIL4 | pole plasm |
| GO:0060293 | 0.000261258639543 | 0.75 | PIWIL1 TDRKH PIWIL4 | germ plasm |
| REAC:R-HSA-211000 | 0.000372329018867 | 0.75 | PIWIL1 TDRKH PIWIL4 | Gene Silencing by RNA |
| GO:0034584 | 0.0028092043205 | 0.5 | PIWIL1 PIWIL4 | piRNA binding |
| GO:0070918 | 0.0100599149475 | 0.75 | PIWIL1 TDRKH PIWIL4 | regulatory ncRNA processing |
| WP:WP4673 | 0.017442995787 | 0.5 | PIWIL1 PIWIL4 | Male infertility |
| GO:0071547 | 0.0280843539964 | 0.5 | PIWIL4 TDRKH | piP-body |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PIWIL4 | TDRKH | 0.908 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ARHGAP19 | TDRKH | 0.834 | 0.138 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PIWIL1 | TDRKH | 0.822 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PIWIL1 | huMAP3_13124.1 huMAP3_13584.1 huMAP3_15119.1 |
| PIWIL4 | huMAP3_13124.1 huMAP3_13584.1 huMAP3_15119.1 |
| TDRKH | huMAP3_13124.1 huMAP3_13584.1 huMAP3_15119.1 |
| ARHGAP19 | huMAP3_00876.1 huMAP3_05648.1 huMAP3_10265.1 huMAP3_12078.1 huMAP3_13124.1 huMAP3_13181.1 huMAP3_14215.1 huMAP3_15119.1 |