hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15129.1
Complex Portal: CPX-22965
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DEFB104A | Beta-defensin 104 (Beta-defensin 4) (BD-4) (DEFB-4) (hBD-4) (Defensin, beta 104) | 5 | UniProt NCBI |
| NTRK3 | NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) | 5 | UniProt NCBI |
| GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7210 | 0.0249718442457 | 0.5 | GNB2 | GNAS-L-GNB2-GNG13 complex |
| HPA:0100213 | 0.038242008944 | 1.0 | NTRK3 GNB2 | cerebral cortex; neuropil[High] |
| REAC:R-HSA-9034013 | 0.0499419797295 | 0.5 | NTRK3 | NTF3 activates NTRK3 signaling |
| CORUM:7205 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG12 complex |
| CORUM:7199 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG11 complex |
| CORUM:7188 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG10 complex |
| CORUM:7171 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG7 complex |
| CORUM:7176 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG8 complex |
| CORUM:7161 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG4 complex |
| CORUM:7153 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG3 complex |
| CORUM:7148 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG2 complex |
| CORUM:7143 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG1 complex |
| CORUM:7093 | 0.0499419797295 | 0.5 | GNB2 | GNAI1-GNB2-GNG13 complex |
| CORUM:7166 | 0.0499419797295 | 0.5 | GNB2 | GNAS-L-GNB2-GNG5 complex |
| HP:0031935 | 0.0499436884913 | 0.5 | GNB2 | Ascending aorta hypoplasia |
| HP:0006659 | 0.0499436884913 | 0.5 | GNB2 | Internally rotated shoulders |
| HP:0006837 | 0.0499436884913 | 0.5 | GNB2 | Congenital Horner syndrome |
| HP:0031909 | 0.0499436884913 | 0.5 | GNB2 | Unicornuate uterus |
| HP:0033992 | 0.0499436884913 | 0.5 | GNB2 | Chronotropic incompetence |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DEFB104A | GNB2 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM | ||
| NTRK3 | GNB2 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes