hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_15146.1

Confidence: Medium

Show entries

Search:

Genename	Protein Name	Uniprot Annotation Score	Links
AZI2	5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (Nap1) (TILP)	5	UniProt NCBI
BBOX1	Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase)	5	UniProt NCBI
BIRC2	Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)	5	UniProt NCBI
BIRC3	Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)	5	UniProt NCBI
CXCL1	Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)]	5	UniProt NCBI
CXCL2	C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)]	5	UniProt NCBI
CXCL3	C-X-C motif chemokine 3 (GRO-gamma(1-73)) (Growth-regulated protein gamma) (GRO-gamma) (Macrophage inflammatory protein 2-beta) (MIP2-beta) [Cleaved into: GRO-gamma(5-73)]	5	UniProt NCBI
DIABLO	Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form]	5	UniProt NCBI
HTRA2	Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)	5	UniProt NCBI
IKBKE	Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)	5	UniProt NCBI

Showing 1 to 10 of 18 entries

Show entries

Search:

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0071345	2.84456120799e-13	0.8125	AZI2 IKBKE BIRC2 TANK TBK1 TBKBP1 BIRC3 TRAF5 TRAF1 IRAK3 TRAF2 HTRA2 CXCL1	cellular response to cytokine stimulus
GO:0019221	1.20900130456e-12	0.75	AZI2 IKBKE BIRC2 TANK TBK1 TBKBP1 BIRC3 TRAF5 TRAF1 IRAK3 TRAF2 CXCL1	cytokine-mediated signaling pathway
GO:0034097	1.32821775596e-12	0.8125	AZI2 IKBKE BIRC2 TANK TBK1 TBKBP1 BIRC3 TRAF5 TRAF1 IRAK3 TRAF2 HTRA2 CXCL1	response to cytokine
CORUM:5212	1.99854789364e-12	0.3125	TANK TBKBP1 TRAF2 AZI2 TBK1	Kinase maturation complex 2
KEGG:04621	5.83360113563e-11	0.5	IKBKE BIRC2 CXCL1 TANK TBK1 BIRC3 TRAF5 TRAF2	NOD-like receptor signaling pathway
WP:WP231	1.96147042255e-10	0.4375	BIRC2 BIRC3 DIABLO TANK TRAF2 TBK1 TRAF1	TNF alpha signaling pathway
GO:0007249	3.6652836327e-10	0.625	IKBKE BIRC2 TANK TBK1 TBKBP1 BIRC3 TRAF5 AZI2 TRAF1 TRAF2	canonical NF-kappaB signal transduction
REAC:R-HSA-5357905	1.19546131579e-09	0.375	BIRC2 TBK1 BIRC3 TRAF2 TRAF1 IKBKE	Regulation of TNFR1 signaling
WP:WP3865	1.65600495644e-09	0.375	IKBKE TBKBP1 AZI2 TANK TRAF2 TBK1	Novel intracellular components of RIG I like receptor pathway
KEGG:04622	2.80263790474e-09	0.375	IKBKE TBKBP1 AZI2 TANK TRAF2 TBK1	RIG-I-like receptor signaling pathway

Showing 1 to 10 of 112 entries

Show entries

Search:

Protein 1	Protein 2	Score	ProteomeHD
TRAF2	TRAF1	1.0	0.088
BIRC2	DIABLO	1.0	0.128
BIRC2	TRAF1	0.999	0.166
TANK	TRAF1	0.999	0.136
TANK	TRAF2	0.999	0.148952380952
BIRC2	TRAF2	0.999	0.2272
AZI2	BBOX1	0.999
TRAF1	TBK1	0.999	0.124
TANK	TBK1	0.998	0.194
BIRC2	HTRA2	0.998	0.124

Showing 1 to 10 of 76 entries

Related Complexes

Genename	Complexes
BIRC2	huMAP3_00079.1 huMAP3_05765.1 huMAP3_07387.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
IKBKE	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
CXCL2	huMAP3_04193.1 huMAP3_11292.1 huMAP3_12588.1 huMAP3_12680.1 huMAP3_13249.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
CXCL1	huMAP3_02215.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12588.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13249.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
IRAK3	huMAP3_11252.1 huMAP3_12343.1 huMAP3_12986.1 huMAP3_13723.1 huMAP3_13879.1 huMAP3_13917.1 huMAP3_15146.1
HTRA2	huMAP3_02517.1 huMAP3_03100.1 huMAP3_03925.1 huMAP3_05775.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_08787.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09818.1 huMAP3_09978.1 huMAP3_10711.1 huMAP3_12700.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1
BIRC3	huMAP3_01302.1 huMAP3_02031.1 huMAP3_02285.1 huMAP3_02517.1 huMAP3_03925.1 huMAP3_05158.1 huMAP3_05694.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_08312.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
CXCL3	huMAP3_02215.1 huMAP3_04193.1 huMAP3_06150.1 huMAP3_09978.1 huMAP3_11292.1 huMAP3_12588.1 huMAP3_12680.1 huMAP3_13249.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
DIABLO	huMAP3_05765.1 huMAP3_06254.1 huMAP3_07387.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
TRAF5	huMAP3_00937.1 huMAP3_02595.1 huMAP3_05172.1 huMAP3_07571.1 huMAP3_08385.1 huMAP3_08640.1 huMAP3_10605.1 huMAP3_10687.1 huMAP3_11771.1 huMAP3_12053.1 huMAP3_12088.1 huMAP3_12986.1 huMAP3_13843.1 huMAP3_13879.1 huMAP3_14423.1 huMAP3_15146.1
SYCN	huMAP3_00477.1 huMAP3_11779.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1
TRAF2	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
TANK	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
TRAF1	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_14463.1 huMAP3_15146.1 huMAP3_15257.1
TBK1	huMAP3_03925.1 huMAP3_06254.1 huMAP3_09536.1 huMAP3_10832.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
BBOX1	huMAP3_02194.1 huMAP3_07956.1 huMAP3_08217.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1
TBKBP1	huMAP3_11248.1 huMAP3_11496.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_14821.1 huMAP3_15146.1 huMAP3_15257.1
AZI2	huMAP3_00422.1 huMAP3_04363.1 huMAP3_08217.1 huMAP3_08972.1 huMAP3_10832.1 huMAP3_12343.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13723.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1