hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_15146.1

Complex Portal: CPX-13954

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
BIRC2	Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)	5	UniProt NCBI
IKBKE	Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)	5	UniProt NCBI
CXCL2	C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)]	5	UniProt NCBI
CXCL1	Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)]	5	UniProt NCBI
IRAK3	Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)	5	UniProt NCBI
HTRA2	Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)	5	UniProt NCBI
BIRC3	Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)	5	UniProt NCBI
CXCL3	C-X-C motif chemokine 3 (GRO-gamma(1-73)) (Growth-regulated protein gamma) (GRO-gamma) (Macrophage inflammatory protein 2-beta) (MIP2-beta) [Cleaved into: GRO-gamma(5-73)]	5	UniProt NCBI
DIABLO	Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form]	5	UniProt NCBI
TRAF5	TNF receptor-associated factor 5 (RING finger protein 84)	5	UniProt NCBI
SYCN	Syncollin (Insulin synthesis-associated protein 1)	2	UniProt NCBI
TRAF2	TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)	5	UniProt NCBI
TANK	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)	5	UniProt NCBI
TRAF1	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)	5	UniProt NCBI
TBK1	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)	5	UniProt NCBI
BBOX1	Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase)	5	UniProt NCBI
TBKBP1	TANK-binding kinase 1-binding protein 1 (TBK1-binding protein 1)	5	UniProt NCBI
AZI2	5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (Nap1) (TILP)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0071345	2.84456120799e-13	0.8125	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	cellular response to cytokine stimulus
GO:0019221	1.20900130456e-12	0.75	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF2 CXCL1 TRAF5	cytokine-mediated signaling pathway
GO:0034097	1.32821775596e-12	0.8125	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	response to cytokine
CORUM:5212	1.99854789364e-12	0.3125	TRAF2 TBKBP1 TANK AZI2 TBK1	Kinase maturation complex 2
KEGG:04621	5.83360113563e-11	0.5	TRAF2 TANK IKBKE BIRC2 BIRC3 TBK1 CXCL1 TRAF5	NOD-like receptor signaling pathway
WP:WP231	1.96147042255e-10	0.4375	TRAF1 TRAF2 TANK DIABLO BIRC2 BIRC3 TBK1	TNF alpha signaling pathway
GO:0007249	3.6652836327e-10	0.625	TRAF1 TRAF2 AZI2 TANK TBKBP1 IKBKE BIRC2 TRAF5 TBK1 BIRC3	canonical NF-kappaB signal transduction
REAC:R-HSA-5357905	1.19546131579e-09	0.375	TRAF1 TRAF2 IKBKE BIRC2 TBK1 BIRC3	Regulation of TNFR1 signaling
WP:WP3865	1.65600495644e-09	0.375	TRAF2 AZI2 TBKBP1 TANK IKBKE TBK1	Novel intracellular components of RIG I like receptor pathway
KEGG:04622	2.80263790474e-09	0.375	TRAF2 AZI2 TBKBP1 TANK IKBKE TBK1	RIG-I-like receptor signaling pathway
REAC:R-HSA-75893	3.86736174768e-09	0.375	TRAF1 TRAF2 IKBKE BIRC2 TBK1 BIRC3	TNF signaling
REAC:R-HSA-166016	7.90735380017e-09	0.4375	BIRC2 TANK IKBKE IRAK3 BIRC3 TRAF2 TBK1	Toll Like Receptor 4 (TLR4) Cascade
REAC:R-HSA-5357786	9.66028385499e-09	0.3125	TBK1 BIRC2 TRAF2 BIRC3 IKBKE	TNFR1-induced proapoptotic signaling
KEGG:04064	1.01065347677e-08	0.375	TRAF1 TRAF2 BIRC2 TRAF5 CXCL1 BIRC3	NF-kappa B signaling pathway
GO:0035631	1.81026995552e-08	0.3125	BIRC2 TRAF5 TRAF2 HTRA2 DIABLO	CD40 receptor complex
REAC:R-HSA-168898	2.19025598657e-08	0.4375	BIRC2 TANK IKBKE IRAK3 BIRC3 TRAF2 TBK1	Toll-like Receptor Cascades
KEGG:04668	2.89729743916e-08	0.375	TRAF1 TRAF2 BIRC2 TRAF5 CXCL1 BIRC3	TNF signaling pathway
WP:WP2036	3.23867863449e-08	0.3125	BIRC2 TRAF1 TRAF2 BIRC3 TRAF5	TNF related weak inducer of apoptosis TWEAK signaling pathway
GO:0071310	4.903126771e-08	0.8125	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	cellular response to organic substance
REAC:R-HSA-168164	1.09803566699e-07	0.375	TRAF2 TANK IKBKE BIRC2 TBK1 BIRC3	Toll Like Receptor 3 (TLR3) Cascade
KEGG:04210	1.19987491825e-07	0.375	TRAF1 TRAF2 DIABLO BIRC2 HTRA2 BIRC3	Apoptosis
REAC:R-HSA-166166	1.25417363658e-07	0.375	TRAF2 TANK IKBKE BIRC2 TBK1 BIRC3	MyD88-independent TLR4 cascade
REAC:R-HSA-937061	1.25417363658e-07	0.375	TRAF2 TANK IKBKE BIRC2 TBK1 BIRC3	TRIF(TICAM1)-mediated TLR4 signaling
WP:WP5039	2.21038193064e-07	0.3125	TBK1 TRAF2 TANK CXCL1 TRAF5	SARS CoV 2 innate immunity evasion and cell specific immune response
GO:0007166	4.26881576982e-07	0.875	TRAF1 BIRC2 AZI2 TBKBP1 DIABLO TANK IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	cell surface receptor signaling pathway
REAC:R-HSA-73887	8.33666340131e-07	0.375	TRAF1 TRAF2 IKBKE BIRC2 TBK1 BIRC3	Death Receptor Signaling
GO:0035556	8.71246612656e-07	0.875	TRAF1 BIRC2 AZI2 TBKBP1 DIABLO TANK IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	intracellular signal transduction
KEGG:04657	8.81038178526e-07	0.3125	TBK1 IKBKE TRAF2 CXCL1 TRAF5	IL-17 signaling pathway
GO:0043122	1.03909274014e-06	0.5	TRAF1 TRAF2 TANK IKBKE BIRC2 TRAF5 TBK1 BIRC3	regulation of canonical NF-kappaB signal transduction
GO:0010033	1.05316934365e-06	0.8125	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	response to organic substance
WP:WP254	1.26069494586e-06	0.3125	BIRC2 TRAF1 TRAF2 BIRC3 DIABLO	Apoptosis
KEGG:04215	1.32724591149e-06	0.25	BIRC2 HTRA2 DIABLO BIRC3	Apoptosis - multiple species
KEGG:05222	1.54419603947e-06	0.3125	BIRC2 TRAF1 TRAF2 BIRC3 TRAF5	Small cell lung cancer
WP:WP4658	3.4489263619e-06	0.3125	BIRC2 TRAF1 TRAF2 BIRC3 TRAF5	Small cell lung cancer
GO:0070887	4.65760406727e-06	0.8125	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	cellular response to chemical stimulus
REAC:R-HSA-933541	6.5430894935e-06	0.25	TBK1 IKBKE TANK TRAF2	TRAF6 mediated IRF7 activation
REAC:R-HSA-5357956	9.88698006292e-06	0.25	BIRC2 TRAF1 BIRC3 TRAF2	TNFR1-induced NF-kappa-B signaling pathway
GO:0140546	1.00243257643e-05	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	defense response to symbiont
GO:0098542	2.11245456803e-05	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	defense response to other organism
CORUM:5529	5.10764421909e-05	0.125	BIRC2 TRAF2	TRAF2-cIAP1/BIRC2 complex
REAC:R-HSA-5676594	5.16619332528e-05	0.1875	BIRC2 BIRC3 TRAF2	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
KEGG:05417	6.22143531759e-05	0.3125	TBK1 IKBKE TANK CXCL1 TRAF2	Lipid and atherosclerosis
GO:0045087	6.51548401626e-05	0.5625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 TBK1	innate immune response
REAC:R-HSA-9013973	6.88366113519e-05	0.1875	IKBKE TANK TBK1	TICAM1-dependent activation of IRF3/IRF7
KEGG:05168	9.23993437067e-05	0.375	TRAF2 BIRC3 BIRC2 TBK1 IKBKE TRAF5	Herpes simplex virus 1 infection
GO:0042221	0.000103261240428	0.8125	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	response to chemical
GO:0051707	0.000112785173941	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	response to other organism
GO:0043207	0.000112785173941	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	response to external biotic stimulus
REAC:R-HSA-936964	0.000113741345606	0.1875	IKBKE TANK TBK1	Activation of IRF3, IRF7 mediated by TBK1, IKBKE
WP:WP1772	0.00014490813841	0.25	BIRC2 HTRA2 DIABLO BIRC3	Apoptosis modulation and signaling
CORUM:5210	0.000153131458895	0.125	TRAF2 TANK	TANK-TRAF2-TRAF3 complex
CORUM:5531	0.000153131458895	0.125	BIRC2 TRAF2	Tumor necrosis factor receptor 1 signaling complex
GO:0009607	0.000154926428392	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	response to biotic stimulus
GO:0071356	0.000156678853324	0.375	TRAF1 TRAF2 TANK BIRC2 BIRC3 TRAF5	cellular response to tumor necrosis factor
GO:0141124	0.000162510764245	0.6875	TRAF1 BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 TRAF5 TBK1 TRAF2 BIRC3	intracellular signaling cassette
GO:0009898	0.00026799570908	0.375	TRAF1 TRAF2 DIABLO BIRC2 TRAF5 HTRA2	cytoplasmic side of plasma membrane
WP:WP3851	0.000271709825145	0.1875	IKBKE TBK1 IRAK3	TLR4 signaling and tolerance
GO:0060337	0.000288967006385	0.3125	IKBKE TBKBP1 TANK AZI2 TBK1	type I interferon-mediated signaling pathway
GO:0034612	0.000304233143671	0.375	TRAF1 TRAF2 TANK BIRC2 BIRC3 TRAF5	response to tumor necrosis factor
GO:0071357	0.000312850704938	0.3125	IKBKE TBKBP1 TANK AZI2 TBK1	cellular response to type I interferon
REAC:R-HSA-168928	0.000324854814064	0.25	TBK1 IKBKE TANK TRAF2	DDX58/IFIH1-mediated induction of interferon-alpha/beta
WP:WP5406	0.000386234928838	0.1875	TRAF2 TRAF5 TRAF1	13q12 12 copy number variation
GO:0044419	0.000401663803349	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	biological process involved in interspecies interaction between organisms
REAC:R-HSA-168249	0.000437316392748	0.5	BIRC2 TANK IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	Innate Immune System
GO:0034340	0.000456972654925	0.3125	IKBKE TBKBP1 TANK AZI2 TBK1	response to type I interferon
GO:0033209	0.000527613283696	0.3125	BIRC2 TRAF1 TRAF2 BIRC3 TRAF5	tumor necrosis factor-mediated signaling pathway
GO:0043123	0.000664681346632	0.375	TRAF2 BIRC3 BIRC2 TBK1 IKBKE TRAF5	positive regulation of canonical NF-kappaB signal transduction
GO:0006952	0.000687386146039	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	defense response
KEGG:04217	0.000730899004263	0.25	BIRC2 TRAF2 BIRC3 TRAF5	Necroptosis
GO:0006955	0.000791667248896	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	immune response
GO:0098562	0.00091543574347	0.375	TRAF1 TRAF2 DIABLO BIRC2 TRAF5 HTRA2	cytoplasmic side of membrane
GO:0140888	0.00122684595838	0.3125	IKBKE TBKBP1 TANK AZI2 TBK1	interferon-mediated signaling pathway
REAC:R-HSA-5213460	0.00125517419044	0.1875	BIRC2 BIRC3 TRAF2	RIPK1-mediated regulated necrosis
REAC:R-HSA-5675482	0.00125517419044	0.1875	BIRC2 BIRC3 TRAF2	Regulation of necroptotic cell death
KEGG:05167	0.00163263874749	0.25	TBK1 IKBKE CXCL1 TRAF2	Kaposi sarcoma-associated herpesvirus infection
WP:WP2018	0.00176831553253	0.1875	TRAF2 TRAF5 TRAF1	RANKL RANK signaling pathway
KEGG:05169	0.00213968018554	0.25	TBK1 IKBKE TRAF5 TRAF2	Epstein-Barr virus infection
WP:WP5116	0.00349028021912	0.125	IKBKE TBK1	SARS CoV 2 B 1 1 7 variant antagonises innate immune activation
GO:1902531	0.0039780635369	0.625	TRAF1 BIRC2 TANK IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 HTRA2	regulation of intracellular signal transduction
GO:0031996	0.00450341440411	0.1875	TRAF2 TRAF5 TRAF1	thioesterase binding
CORUM:6344	0.00461246285552	0.125	TRAF2 BIRC3	TNF-R1-associated signaling complex
KEGG:05200	0.00507404086882	0.3125	BIRC2 TRAF1 TRAF2 BIRC3 TRAF5	Pathways in cancer
REAC:R-HSA-5218859	0.00713191639651	0.1875	BIRC2 BIRC3 TRAF2	Regulated Necrosis
REAC:R-HSA-1280215	0.00835999888012	0.375	TRAF2 IRAK3 BIRC2 BIRC3 CXCL1 TBK1	Cytokine Signaling in Immune system
GO:1902554	0.00890145696994	0.3125	IKBKE TBKBP1 TANK AZI2 TBK1	serine/threonine protein kinase complex
GO:0098802	0.0100128127401	0.3125	BIRC2 TRAF5 TRAF2 HTRA2 DIABLO	plasma membrane signaling receptor complex
GO:0007165	0.010126465611	0.875	TRAF1 BIRC2 AZI2 TBKBP1 DIABLO TANK IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	signal transduction
WP:WP5182	0.0113000203587	0.125	TRAF2 BIRC3	Pro survival signaling of neuroprotectin D1
REAC:R-HSA-5357801	0.0141363635802	0.25	BIRC2 TRAF2 BIRC3 DIABLO	Programmed Cell Death
GO:0070534	0.0146549762917	0.25	BIRC2 TRAF1 TRAF5 TRAF2	protein K63-linked ubiquitination
GO:0009615	0.015639812058	0.375	IRAK3 AZI2 TBKBP1 TANK IKBKE TBK1	response to virus
GO:0065009	0.0164953292088	0.625	TRAF1 BIRC2 DIABLO TANK IKBKE IRAK3 BIRC3 TRAF5 TRAF2 HTRA2	regulation of molecular function
GO:1902911	0.0167425726181	0.3125	IKBKE TBKBP1 TANK AZI2 TBK1	protein kinase complex
KEGG:04936	0.0182647337957	0.1875	IKBKE CXCL1 TBK1	Alcoholic liver disease
WP:WP4961	0.0189504620679	0.125	IKBKE TBK1	STING pathway in Kawasaki like disease and COVID 19
WP:WP2507	0.0211664067834	0.125	HTRA2 DIABLO	Nanomaterial induced apoptosis
KEGG:05160	0.0214634491342	0.1875	IKBKE TBK1 TRAF2	Hepatitis C
GO:0034121	0.0242959882477	0.1875	BIRC2 BIRC3 IRAK3	regulation of toll-like receptor signaling pathway
GO:0009605	0.026500423105	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	response to external stimulus
GO:0023052	0.0292918197435	0.875	TRAF1 BIRC2 AZI2 TBKBP1 DIABLO TANK IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	signaling
REAC:R-HSA-918233	0.0296708136905	0.125	IKBKE TBK1	TRAF3-dependent IRF activation pathway
GO:0002376	0.0302329747754	0.625	BIRC2 AZI2 TANK TBKBP1 IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	immune system process
REAC:R-HSA-5668541	0.0304776271965	0.1875	BIRC2 BIRC3 TRAF2	TNFR2 non-canonical NF-kB pathway
WP:WP4868	0.0312364916034	0.125	IKBKE TBK1	Type I interferon induction and signaling during SARS CoV 2 infection
GO:0007154	0.0345151227914	0.875	TRAF1 BIRC2 AZI2 TBKBP1 DIABLO TANK IKBKE IRAK3 BIRC3 TBK1 TRAF5 TRAF2 CXCL1 HTRA2	cell communication
KEGG:05202	0.0351133870028	0.1875	BIRC2 BIRC3 TRAF1	Transcriptional misregulation in cancer
WP:WP4950	0.0400491403785	0.125	TRAF2 TRAF1	16p11 2 distal deletion syndrome
GO:0051091	0.0406924925344	0.3125	IKBKE TRAF1 TRAF2 TRAF5 IRAK3	positive regulation of DNA-binding transcription factor activity
WP:WP3858	0.0432254649743	0.125	IKBKE TBK1	Toll like receptor signaling related to MyD88
REAC:R-HSA-168256	0.0495670440802	0.5	BIRC2 TANK IKBKE IRAK3 BIRC3 TRAF2 CXCL1 TBK1	Immune System
WP:WP4880	0.0499348849842	0.125	IKBKE TBK1	Host pathogen interaction of human coronaviruses interferon induction
WP:WP5038	0.0499348849842	0.125	IKBKE TBK1	Mitochondrial immune response to SARS CoV 2

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
TRAF2	TRAF1	1.0	0.088	structurally_consistent (dimer)
BIRC2	DIABLO	1.0	0.128
BIRC2	TRAF1	0.999	0.166	structurally_consistent (dimer)
TANK	TRAF1	0.999	0.136
TANK	TRAF2	0.999	0.148952380952
BIRC2	TRAF2	0.999	0.2272	mutually_exclusive (Q13077)
AZI2	BBOX1	0.999
TRAF1	TBK1	0.999	0.124
TANK	TBK1	0.998	0.194
BIRC2	HTRA2	0.998	0.124
TRAF2	TBK1	0.998	0.06
CXCL3	CXCL2	0.998		mutually_exclusive (P09341) structurally_consistent (dimer)
BBOX1	TBK1	0.997
BBOX1	TANK	0.997
TRAF2	DIABLO	0.996	0.074	structurally_consistent (dimer)
BIRC2	CXCL1	0.995
HTRA2	TRAF2	0.994	0.034
TANK	DIABLO	0.993	0.128
AZI2	TBK1	0.99	0.12
CXCL1	TRAF2	0.987
TRAF1	DIABLO	0.986	0.168
CXCL1	TBK1	0.984
TANK	IKBKE	0.98
HTRA2	TRAF1	0.98	0.092
TRAF2	IKBKE	0.976
HTRA2	DIABLO	0.973	0.374
CXCL3	CXCL1	0.972		mutually_exclusive (P19875) structurally_consistent (dimer)
BIRC3	TRAF2	0.969		mutually_exclusive (Q9NR28)
BIRC3	TRAF1	0.966
BIRC3	DIABLO	0.964		structurally_consistent (dimer)
BIRC2	TANK	0.955	0.172
HTRA2	TANK	0.952	0.096
CXCL1	DIABLO	0.952
BIRC2	TBK1	0.939	0.184
CXCL3	TRAF2	0.928
AZI2	IRAK3	0.921	0.132
CXCL1	CXCL2	0.894		mutually_exclusive (P19876) structurally_consistent (dimer)
BIRC3	IKBKE	0.892
TRAF5	TANK	0.886	0.14
AZI2	TANK	0.874	0.162
BIRC2	SYCN	0.862
TBK1	DIABLO	0.858	0.052
TBK1	TBKBP1	0.85
BIRC2	CXCL3	0.797
TRAF1	IKBKE	0.796
BIRC2	IKBKE	0.492
TBK1	IRAK3	0.483	0.114
IKBKE	TBK1	0.456		structurally_consistent (dimer)
HTRA2	IKBKE	0.451
BIRC2	BIRC3	0.438
BIRC3	TANK	0.384
IKBKE	DIABLO	0.374
BIRC3	TBK1	0.373
AZI2	TBKBP1	0.371
TRAF2	CXCL2	0.334
BIRC3	HTRA2	0.306
HTRA2	TBK1	0.277	0.042
SYCN	TRAF2	0.186
TRAF5	TBKBP1	0.138
TRAF5	IKBKE	0.113
BIRC2	CXCL2	0.105
TRAF5	TRAF1	0.076	0.148
BIRC2	TRAF5	0.064	0.152
TRAF5	HTRA2	0.053	0.06
AZI2	HTRA2	0.052	0.09
TRAF5	TRAF2	0.051	0.126
CXCL1	TANK	0.043
AZI2	DIABLO	0.022	0.102
HTRA2	TBKBP1	0.022
TRAF2	TBKBP1	0.022
SYCN	HTRA2	0.02
TRAF5	TBK1	0.02	0.13
TRAF5	DIABLO	0.016	0.136
DIABLO	TBKBP1	0.015
AZI2	TRAF2	0.014	0.158
AZI2	TRAF5	0.014	0.094

Related Complexes

Genename	Complexes
BIRC2	huMAP3_00079.1 huMAP3_05765.1 huMAP3_07387.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
IKBKE	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
CXCL2	huMAP3_04193.1 huMAP3_11292.1 huMAP3_12588.1 huMAP3_12680.1 huMAP3_13249.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
CXCL1	huMAP3_02215.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12588.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13249.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
IRAK3	huMAP3_11252.1 huMAP3_12343.1 huMAP3_12986.1 huMAP3_13723.1 huMAP3_13879.1 huMAP3_13917.1 huMAP3_15146.1
HTRA2	huMAP3_02517.1 huMAP3_03100.1 huMAP3_03925.1 huMAP3_05775.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_08787.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09818.1 huMAP3_09978.1 huMAP3_10711.1 huMAP3_12700.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1
BIRC3	huMAP3_01302.1 huMAP3_02031.1 huMAP3_02285.1 huMAP3_02517.1 huMAP3_03925.1 huMAP3_05158.1 huMAP3_05694.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_08312.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
CXCL3	huMAP3_02215.1 huMAP3_04193.1 huMAP3_06150.1 huMAP3_09978.1 huMAP3_11292.1 huMAP3_12588.1 huMAP3_12680.1 huMAP3_13249.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
DIABLO	huMAP3_05765.1 huMAP3_06254.1 huMAP3_07387.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
TRAF5	huMAP3_00937.1 huMAP3_02595.1 huMAP3_05172.1 huMAP3_07571.1 huMAP3_08385.1 huMAP3_08640.1 huMAP3_10605.1 huMAP3_10687.1 huMAP3_11771.1 huMAP3_12053.1 huMAP3_12088.1 huMAP3_12986.1 huMAP3_13843.1 huMAP3_13879.1 huMAP3_14423.1 huMAP3_15146.1
SYCN	huMAP3_00477.1 huMAP3_11779.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1
TRAF2	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
TANK	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
TRAF1	huMAP3_02517.1 huMAP3_03925.1 huMAP3_06254.1 huMAP3_06826.1 huMAP3_08034.1 huMAP3_09205.1 huMAP3_09536.1 huMAP3_09978.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_14463.1 huMAP3_15146.1 huMAP3_15257.1
TBK1	huMAP3_03925.1 huMAP3_06254.1 huMAP3_09536.1 huMAP3_10832.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1
BBOX1	huMAP3_02194.1 huMAP3_07956.1 huMAP3_08217.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_15146.1
TBKBP1	huMAP3_11248.1 huMAP3_11496.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13879.1 huMAP3_14821.1 huMAP3_15146.1 huMAP3_15257.1
AZI2	huMAP3_00422.1 huMAP3_04363.1 huMAP3_08217.1 huMAP3_08972.1 huMAP3_10832.1 huMAP3_12343.1 huMAP3_12680.1 huMAP3_12986.1 huMAP3_13723.1 huMAP3_13879.1 huMAP3_15146.1 huMAP3_15257.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_15146.1

Complex Portal: CPX-13954