hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15147.1
Complex Portal: CPX-21845
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNMB3 | Calcium-activated potassium channel subunit beta-3 (BK channel subunit beta-3) (BKbeta3) (Hbeta3) (Calcium-activated potassium channel, subfamily M subunit beta-3) (Charybdotoxin receptor subunit beta-3) (K(VCA)beta-3) (Maxi K channel subunit beta-3) (Slo-beta-3) | 5 | UniProt NCBI |
| KCNJ12 | ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12) | 5 | UniProt NCBI |
| SMPD2 | Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Lyso-platelet-activating factor-phospholipase C) (Lyso-PAF-PLC) (Neutral sphingomyelinase) (N-SMase) (nSMase) (nSMase1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296071 | 0.0145828870271 | 0.666666666667 | KCNMB3 KCNJ12 | Potassium Channels |
| REAC:R-HSA-193681 | 0.0498224659464 | 0.333333333333 | SMPD2 | Ceramide signalling |
| REAC:R-HSA-1296053 | 0.0498224659464 | 0.333333333333 | KCNJ12 | Classical Kir channels |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNJ12 | KCNMB3 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNMB3 | SMPD2 | 0.902 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNJ12 | SMPD2 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes