hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15148.1
Complex Portal: CPX-22380
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LIFR | Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) | 5 | UniProt NCBI |
| CTF1 | Cardiotrophin-1 (CT-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1528 | 8.93837738341e-05 | 1.0 | LIFR CTF1 | Physiological and pathological hypertrophy of the heart |
| REAC:R-HSA-6788467 | 0.000133283416666 | 1.0 | LIFR CTF1 | IL-6-type cytokine receptor ligand interactions |
| REAC:R-HSA-6783589 | 0.000292198259614 | 1.0 | LIFR CTF1 | Interleukin-6 family signaling |
| WP:WP4538 | 0.000753377522316 | 1.0 | LIFR CTF1 | Regulatory circuits of the STAT3 signaling pathway |
| KEGG:04630 | 0.00138428094844 | 1.0 | LIFR CTF1 | JAK-STAT signaling pathway |
| KEGG:04060 | 0.0031385705215 | 1.0 | LIFR CTF1 | Cytokine-cytokine receptor interaction |
| CORUM:5579 | 0.0499419797295 | 0.5 | LIFR | CNTF-CNTFR-gp130-LIFR complex |
| CORUM:5582 | 0.0499419797295 | 0.5 | LIFR | LIFR-LIF-gp130 complex |
| HP:0004980 | 0.0499436884913 | 0.5 | LIFR | Metaphyseal rarefaction |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LIFR | CTF1 | 0.936 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes