hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15154.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LONP2 | Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon) | 5 | UniProt NCBI |
| IL2 | Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin) | 5 | UniProt NCBI |
| IL17A | Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5285 | 0.000367738611184 | 0.666666666667 | IL2 IL17A | Immune infiltration in pancreatic cancer |
| KEGG:05321 | 0.000688034410789 | 0.666666666667 | IL2 IL17A | Inflammatory bowel disease |
| WP:WP5130 | 0.00180332266367 | 0.666666666667 | IL2 IL17A | Th17 cell differentiation pathway |
| WP:WP2328 | 0.00249706944772 | 0.666666666667 | IL2 IL17A | Allograft rejection |
| KEGG:04659 | 0.00304502569943 | 0.666666666667 | IL2 IL17A | Th17 cell differentiation |
| WP:WP5098 | 0.00304949085786 | 0.666666666667 | IL2 IL17A | T cell activation SARS CoV 2 |
| WP:WP5095 | 0.0039339723602 | 0.666666666667 | IL2 IL17A | Overview of proinflammatory and profibrotic mediators |
| KEGG:04060 | 0.0146065267115 | 0.666666666667 | IL2 IL17A | Cytokine-cytokine receptor interaction |
| WP:WP5256 | 0.0331010360575 | 0.333333333333 | IL17A | COVID 19 and endothelial cell senescence |
| CORUM:1707 | 0.0499402709677 | 0.333333333333 | IL2 | IL2-IL2RA-IL2RB complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IL2 | IL17A | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LONP2 | IL17A | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LONP2 | IL2 | 0.855 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| LONP2 | huMAP3_02449.1 huMAP3_07658.1 huMAP3_15154.1 |
| IL2 | huMAP3_03030.1 huMAP3_09900.1 huMAP3_15154.1 |
| IL17A | huMAP3_03030.1 huMAP3_09900.1 huMAP3_15154.1 |