hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15158.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CARD16 | Caspase recruitment domain-containing protein 16 (Caspase recruitment domain-only protein 1) (CARD-only protein 1) (Caspase-1 inhibitor COP) (Pseudo interleukin-1 beta converting enzyme) (Pseudo-ICE) (Pseudo-IL1B-converting enzyme) | 5 | UniProt NCBI |
| CASP12 | Inactive caspase-12 (CASP-12) | 5 | UniProt NCBI |
| FMN2 | Formin-2 | 5 | UniProt NCBI |
| CASP1 | Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04621 | 0.00802719593767 | 0.666666666667 | CARD16 CASP12 | NOD-like receptor signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CASP12 | CASP1 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CASP1 | FMN2 | 0.939 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CASP1 | CARD16 | 0.928 | 0.168 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| CASP12 | FMN2 | 0.303 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes