hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15172.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHP2 | Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520) | 5 | UniProt NCBI |
| GLT1D1 | Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-) | 3 | UniProt NCBI |
| ASAH1 | Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] | 5 | UniProt NCBI |
| CYP1A2 | Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2646 | 0.0248784837172 | 0.25 | CYP1A2 | Lidocaine metabolism |
| CORUM:7098 | 0.0249718442456 | 0.25 | ASAH1 | ASAH1-NR5A1 complex |
| WP:WP2542 | 0.049746753544 | 0.25 | CYP1A2 | Sulindac metabolic pathway |
| WP:WP3633 | 0.049746753544 | 0.25 | CYP1A2 | Caffeine and theobromine metabolism |
| WP:WP694 | 0.049746753544 | 0.25 | CYP1A2 | Arylamine metabolism |
| CORUM:7099 | 0.049938562206 | 0.25 | ASAH1 | ASAH1-NR5A1-SAPD complex |
| REAC:R-HSA-211957 | 0.0499436884912 | 0.25 | CYP1A2 | Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ASAH1 | GLT1D1 | 0.934 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ASAH1 | CHP2 | 0.927 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ASAH1 | CYP1A2 | 0.893 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes