hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15192.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GAGE2D | G antigen 2D (GAGE-2D) (Cancer/testis antigen 4.8) (CT4.8) (G antigen 8) (GAGE-8) | 2 | UniProt NCBI |
| CDYL2 | Chromodomain Y-like protein 2 (CDY-like 2) | 3 | UniProt NCBI |
| ZNF644 | Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2) | 5 | UniProt NCBI |
| XAGE3 | X antigen family member 3 (XAGE-3) (Cancer/testis antigen 12.3) (CT12.3) (G antigen family D member 4) (Placenta-specific gene 6 protein) | 3 | UniProt NCBI |
| MIER2 | Mesoderm induction early response protein 2 (Mi-er2) | 5 | UniProt NCBI |
| APOC2 | Apolipoprotein C-II (Apo-CII) (ApoC-II) (Apolipoprotein C2) [Cleaved into: Proapolipoprotein C-II (ProapoC-II)] | 5 | UniProt NCBI |
| WIZ | Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803) | 5 | UniProt NCBI |
| GMCL1 | Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29) | 5 | UniProt NCBI |
| ZNF462 | Zinc finger protein 462 (Zinc finger PBX1-interacting protein) (ZFPIP) | 5 | UniProt NCBI |
| EHMT2 | Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a) | 5 | UniProt NCBI |
| EHMT1 | Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D) | 5 | UniProt NCBI |
| XAGE2 | X antigen family member 2 (XAGE-2) (Cancer/testis antigen 12.2) (CT12.2) (G antigen family D member 3) | 3 | UniProt NCBI |
| THOP1 | Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78) | 5 | UniProt NCBI |
| ZBTB46 | Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:643 | 0.00147201837296 | 0.153846153846 | EHMT2 EHMT1 | CtBP core complex |
| CORUM:1194 | 0.00269463984543 | 0.153846153846 | EHMT2 EHMT1 | E2F-6 complex |
| GO:0001222 | 0.00274700202473 | 0.307692307692 | EHMT2 EHMT1 ZNF644 WIZ | transcription corepressor binding |
| CORUM:642 | 0.00553867464003 | 0.153846153846 | EHMT2 EHMT1 | CtBP complex |
| WP:WP4288 | 0.0144668298298 | 0.153846153846 | EHMT2 EHMT1 | MTHFR deficiency |
| REAC:R-HSA-6804760 | 0.0302886092005 | 0.153846153846 | EHMT2 EHMT1 | Regulation of TP53 Activity through Methylation |
| CORUM:860 | 0.0499717467432 | 0.0769230769231 | EHMT2 | DNMT1-EHMT2-PCNA complex |
| CORUM:862 | 0.0499717467432 | 0.0769230769231 | EHMT2 | DNMT1-EHMT2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| EHMT1 | WIZ | 1.0 | |
| ZNF644 | EHMT2 | 1.0 | 0.104 |
| WIZ | XAGE2 | 1.0 | |
| ZNF644 | WIZ | 0.999 | |
| EHMT2 | WIZ | 0.999 | |
| XAGE3 | WIZ | 0.999 | |
| ZNF644 | EHMT1 | 0.999 | 0.194 |
| ZNF644 | XAGE2 | 0.999 | |
| EHMT1 | XAGE2 | 0.999 | |
| XAGE3 | EHMT1 | 0.999 | |
| EHMT2 | XAGE2 | 0.999 | |
| XAGE3 | EHMT2 | 0.999 | |
| EHMT2 | EHMT1 | 0.998 | 0.708 |
| ZNF644 | XAGE3 | 0.998 | |
| CDYL2 | MIER2 | 0.997 | 0.086 |
| ZNF462 | XAGE2 | 0.996 | |
| ZNF462 | WIZ | 0.994 | |
| GMCL1 | XAGE2 | 0.994 | |
| ZNF462 | EHMT2 | 0.988 | 0.15 |
| ZNF462 | EHMT1 | 0.985 | 0.132 |
| EHMT2 | MIER2 | 0.982 | 0.104 |
| EHMT1 | MIER2 | 0.975 | 0.082 |
| CDYL2 | WIZ | 0.974 | |
| EHMT1 | GAGE2D | 0.967 | |
| GAGE2D | WIZ | 0.966 | |
| EHMT2 | GAGE2D | 0.959 | |
| THOP1 | XAGE2 | 0.956 | |
| MIER2 | WIZ | 0.955 | |
| ZNF644 | ZNF462 | 0.954 | 0.112 |
| GAGE2D | GMCL1 | 0.924 | |
| ZNF644 | GAGE2D | 0.914 | |
| XAGE3 | APOC2 | 0.868 | |
| EHMT1 | ZBTB46 | 0.849 | |
| EHMT2 | ZBTB46 | 0.843 | |
| ZNF644 | MIER2 | 0.821 | 0.064 |
| XAGE3 | GMCL1 | 0.82 | |
| EHMT2 | CDYL2 | 0.719 | 0.094 |
| EHMT1 | CDYL2 | 0.719 | 0.088 |
| WIZ | GMCL1 | 0.622 | |
| EHMT1 | GMCL1 | 0.598 | |
| ZNF644 | GMCL1 | 0.516 | |
| ZNF644 | CDYL2 | 0.467 | 0.096 |
| ZNF462 | GMCL1 | 0.356 | |
| WIZ | ZBTB46 | 0.302 | |
| EHMT2 | GMCL1 | 0.179 | |
| EHMT1 | APOC2 | 0.116 | |
| WIZ | APOC2 | 0.102 | |
| GMCL1 | APOC2 | 0.097 | |
| EHMT2 | APOC2 | 0.085 | |
| ZNF462 | THOP1 | 0.083 | 0.072 |
| WIZ | THOP1 | 0.057 | |
| ZNF644 | APOC2 | 0.056 | |
| THOP1 | GMCL1 | 0.042 | |
| EHMT2 | THOP1 | 0.037 | 0.058 |
| EHMT1 | THOP1 | 0.022 | 0.04 |
| ZNF644 | THOP1 | 0.021 | 0.034 |
| MIER2 | THOP1 | 0.009 | 0.058 |
Related Complexes