hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_15239.1

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
ADCYAP1	Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)]	5	UniProt NCBI
C1orf115	Required for drug-induced death protein 1	3	UniProt NCBI
CIRBP	Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)	5	UniProt NCBI
COPRS	Coordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1)	5	UniProt NCBI
FARP2	FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)	5	UniProt NCBI
KRT4	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Type-II keratin Kb4)	5	UniProt NCBI
PPP1R14A	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (Protein kinase C-potentiated inhibitor protein of 17 kDa) (CPI-17)	4	UniProt NCBI
PRMT5	Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]	5	UniProt NCBI
RENBP	N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP)	5	UniProt NCBI
RIOK1	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)	5	UniProt NCBI

Showing 1 to 10 of 12 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6853	3.75927585468e-05	0.166666666667	COPRS PRMT5	COPRS-PRMT5 complex
CORUM:837	0.000112726824524	0.166666666667	WDR77 PRMT5	MEP50-PRMT5-ICLN complex
CORUM:2838	0.000112726824524	0.166666666667	WDR77 PRMT5	MEP50-PRMT5-ICLN complex
CORUM:6852	0.000225350794349	0.166666666667	COPRS PRMT5	COPRS-PRMT5-RUNX1-CBFB complex
CORUM:6858	0.000375413311943	0.166666666667	WDR77 PRMT5	CHTOP-methylosome complex
CORUM:810	0.00078764880341	0.166666666667	WDR77 PRMT5	FCP1-associated protein complex
CORUM:811	0.00078764880341	0.166666666667	WDR77 PRMT5	FCP1-associated protein complex
REAC:R-HSA-3214858	0.00584044581838	0.25	COPRS PRMT5 WDR77	RMTs methylate histone arginines
GO:0048026	0.0203399151593	0.25	WDR77 PRMT5 CIRBP	positive regulation of mRNA splicing, via spliceosome
GO:0050685	0.0423869429414	0.25	WDR77 PRMT5 CIRBP	positive regulation of mRNA processing

Showing 1 to 10 of 12 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
COPRS	WDR77	0.999	0.156	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM boldt_WMM WMM_only
PRMT5	WDR77	0.999	0.914	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM
COPRS	RIOK1	0.999	0.068	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM WMM_only
COPRS	PRMT5	0.996	0.132	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM boldt_WMM
PRMT5	RIOK1	0.994	0.214	hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM
RIOK1	WDR77	0.994	0.196	hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only
CIRBP	WDR77	0.993	0.022	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
RENBP	TINAGL1	0.984	0.074	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
COPRS	FARP2	0.983	0.164	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
COPRS	CIRBP	0.981	0.032	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116

Showing 1 to 10 of 38 entries

Related Complexes

Genename	Complexes
TINAGL1	huMAP3_04155.1 huMAP3_15239.1
KRT4	huMAP3_12619.1 huMAP3_15239.1
PRMT5	huMAP3_02247.1 huMAP3_02465.1 huMAP3_03342.1 huMAP3_06511.1 huMAP3_08980.1 huMAP3_11121.1 huMAP3_15239.1
COPRS	huMAP3_00001.1 huMAP3_02741.1 huMAP3_03342.1 huMAP3_07372.1 huMAP3_11121.1 huMAP3_15239.1
FARP2	huMAP3_00001.1 huMAP3_03342.1 huMAP3_11121.1 huMAP3_15239.1
RIOK1	huMAP3_02247.1 huMAP3_02465.1 huMAP3_03342.1 huMAP3_06511.1 huMAP3_08980.1 huMAP3_11121.1 huMAP3_15239.1
WDR77	huMAP3_02247.1 huMAP3_02465.1 huMAP3_03342.1 huMAP3_06511.1 huMAP3_08980.1 huMAP3_11121.1 huMAP3_15239.1
RENBP	huMAP3_04155.1 huMAP3_12287.1 huMAP3_15239.1
CIRBP	huMAP3_00292.1 huMAP3_02247.1 huMAP3_03342.1 huMAP3_10873.1 huMAP3_11026.1 huMAP3_11121.1 huMAP3_15239.1
ADCYAP1	huMAP3_01572.1 huMAP3_03135.1 huMAP3_07584.1 huMAP3_08940.1 huMAP3_10238.1 huMAP3_10622.1 huMAP3_10953.1 huMAP3_14041.1 huMAP3_15239.1
PPP1R14A	huMAP3_15239.1
C1orf115	huMAP3_01919.1 huMAP3_08468.1 huMAP3_09559.1 huMAP3_11981.1 huMAP3_13628.1 huMAP3_14890.1 huMAP3_15239.1