hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15248.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| POTEJ | POTE ankyrin domain family member J | 4 | UniProt NCBI |
| UBC | Polyubiquitin-C [Cleaved into: Ubiquitin] | 5 | UniProt NCBI |
| MRTFA | Myocardin-related transcription factor A (MRTF-A) (MKL/myocardin-like protein 1) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein) | 5 | UniProt NCBI |
| BCL7C | B-cell CLL/lymphoma 7 protein family member C | 4 | UniProt NCBI |
| SPIRE2 | Protein spire homolog 2 (Spir-2) | 5 | UniProt NCBI |
| CAP1 | Adenylyl cyclase-associated protein 1 (CAP 1) | 5 | UniProt NCBI |
| CAP2 | Adenylyl cyclase-associated protein 2 (CAP 2) | 5 | UniProt NCBI |
| SPIRE1 | Protein spire homolog 1 (Spir-1) | 5 | UniProt NCBI |
| BCL7A | B-cell CLL/lymphoma 7 protein family member A | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-428890 | 0.00223242997382 | 0.222222222222 | CAP1 CAP2 | Role of ABL in ROBO-SLIT signaling |
| GO:2000781 | 0.00463414518632 | 0.444444444444 | BCL7C BCL7A SPIRE2 SPIRE1 | positive regulation of double-strand break repair |
| GO:0045739 | 0.0263809026071 | 0.444444444444 | BCL7C BCL7A SPIRE2 SPIRE1 | positive regulation of DNA repair |
| GO:2000779 | 0.0263809026071 | 0.444444444444 | BCL7C BCL7A SPIRE2 SPIRE1 | regulation of double-strand break repair |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CAP2 | CAP1 | 1.0 | 0.416 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| CAP2 | UBC | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CAP1 | BCL7C | 0.993 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| BCL7A | POTEJ | 0.99 | 0.028 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| BCL7A | BCL7C | 0.99 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CAP2 | BCL7C | 0.986 | 0.032 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SPIRE2 | BCL7A | 0.985 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CAP2 | BCL7A | 0.969 | 0.076 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| MRTFA | BCL7A | 0.969 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| BCL7C | SPIRE1 | 0.964 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CAP2 | POTEJ | 0.955 | 0.026 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| CAP1 | BCL7A | 0.951 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| BCL7A | SPIRE1 | 0.933 | 0.1 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| UBC | POTEJ | 0.902 | bioplex3_WMM WMM_only | |
| SPIRE2 | BCL7C | 0.873 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| SPIRE2 | SPIRE1 | 0.781 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| CAP1 | UBC | 0.591 | bioplex3_WMM WMM_only boldt_WMM | |
| CAP2 | SPIRE1 | 0.559 | 0.03 | bioplex_WMM bioplex3_WMM WMM_only |
| CAP2 | SPIRE2 | 0.527 | bioplex_WMM bioplex3_WMM WMM_only | |
| CAP1 | POTEJ | 0.46 | 0.044 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| MRTFA | BCL7C | 0.349 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only |
| CAP1 | SPIRE2 | 0.29 | bioplex_WMM bioplex3_WMM WMM_only | |
| CAP1 | SPIRE1 | 0.245 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| BCL7C | POTEJ | 0.188 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
| SPIRE2 | POTEJ | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | |
| POTEJ | SPIRE1 | 0.172 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only |
| MRTFA | SPIRE2 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | |
| CAP2 | MRTFA | 0.164 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only |
| MRTFA | SPIRE1 | 0.164 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only |
| MRTFA | POTEJ | 0.164 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| CAP1 | MRTFA | 0.067 | 0.046 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes