hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15260.1
Complex Portal: CPX-18369
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ETV5 | ETS translocation variant 5 (Ets-related protein ERM) | 5 | UniProt   NCBI |
| ATF2 | Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1) | 5 | UniProt   NCBI |
| BATF3 | Basic leucine zipper transcriptional factor ATF-like 3 (B-ATF-3) (21 kDa small nuclear factor isolated from T-cells) (Jun dimerization protein p21SNFT) | 5 | UniProt   NCBI |
| DET1 | DET1 homolog (De-etiolated-1 homolog) | 5 | UniProt   NCBI |
| WASHC1 | WASH complex subunit 1 (CXYorf1-like protein on chromosome 9) (Protein FAM39E) (WAS protein family homolog 1) | 5 | UniProt   NCBI |
| ETV1 | ETS translocation variant 1 (Ets-related protein 81) | 5 | UniProt   NCBI |
| VARS1 | Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) | 5 | UniProt   NCBI |
| FOS | Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos) | 5 | UniProt   NCBI |
| FOSL2 | Fos-related antigen 2 (FRA-2) | 5 | UniProt   NCBI |
| BACH2 | Transcription regulator protein BACH2 (BTB and CNC homolog 2) | 5 | UniProt   NCBI |
| TRIB1 | Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1) | 5 | UniProt   NCBI |
| FOSL1 | Fos-related antigen 1 (FRA-1) | 5 | UniProt   NCBI |
| UBE2E2 | Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) | 5 | UniProt   NCBI |
| CREB5 | Cyclic AMP-responsive element-binding protein 5 (CREB-5) (cAMP-responsive element-binding protein 5) (cAMP-response element-binding protein A) (CRE-BPa) | 5 | UniProt   NCBI |
| CEBPG | CCAAT/enhancer-binding protein gamma (C/EBP gamma) | 5 | UniProt   NCBI |
| TRIB2 | Tribbles homolog 2 (TRB-2) | 5 | UniProt   NCBI |
| JUND | Transcription factor JunD (Transcription factor AP-1 subunit JunD) | 5 | UniProt   NCBI |
| EGR1 | Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24) | 5 | UniProt   NCBI |
| COP1 | E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2) | 5 | UniProt   NCBI |
| ATF3 | Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3) | 5 | UniProt   NCBI |
| EEF1D | Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) | 5 | UniProt   NCBI |
| JUN | Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39) | 5 | UniProt   NCBI |
| STK40 | Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495) | 5 | UniProt   NCBI |
| FOSB | Protein FosB (FosB proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 3) (Transcription factor AP-1 subunit FosB) | 5 | UniProt   NCBI |
| ETS2 | Protein C-ets-2 | 5 | UniProt   NCBI |
| JUNB | Transcription factor JunB (Transcription factor AP-1 subunit JunB) | 5 | UniProt   NCBI |
| UBE2E1 | Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1) | 5 | UniProt   NCBI |
| ATF7 | Cyclic AMP-dependent transcription factor ATF-7 (cAMP-dependent transcription factor ATF-7) (Activating transcription factor 7) (Transcription factor ATF-A) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   REAC:R-HSA-9031628 | 2.30764929541e-07 | 0.238095238095 | TRIB1 EGR1 FOSB FOS JUND | NGF-stimulated transcription |
|   GO:0000981 | 7.45901583889e-07 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | DNA-binding transcription factor activity, RNA polymerase II-specific |
|   GO:0000977 | 1.06453645456e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
|   GO:0003700 | 1.63147429471e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | DNA-binding transcription factor activity |
|   GO:0000785 | 2.84253046962e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | chromatin |
|   GO:0000976 | 3.11047278325e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | transcription cis-regulatory region binding |
|   GO:0001067 | 3.1505845936e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | transcription regulatory region nucleic acid binding |
|   REAC:R-HSA-198725 | 3.55189258482e-06 | 0.238095238095 | TRIB1 EGR1 FOSB FOS JUND | Nuclear Events (kinase and transcription factor activation) |
|   GO:0000978 | 3.63772552334e-06 | 0.571428571429 | EGR1 ATF7 BATF3 BACH2 CEBPG JUND ETV1 ATF3 CREB5 FOSB FOS JUN | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
|   GO:0000987 | 4.62891448098e-06 | 0.571428571429 | EGR1 ATF7 BATF3 BACH2 CEBPG JUND ETV1 ATF3 CREB5 FOSB FOS JUN | cis-regulatory region sequence-specific DNA binding |
|   GO:1990837 | 5.59900030278e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | sequence-specific double-stranded DNA binding |
|   GO:0032993 | 5.95032699563e-06 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | protein-DNA complex |
|   GO:0090575 | 1.13730233703e-05 | 0.380952380952 | ATF7 BATF3 JUND CEBPG BACH2 ATF3 FOS JUN | RNA polymerase II transcription regulator complex |
|   GO:0043565 | 1.36742305262e-05 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | sequence-specific DNA binding |
|   GO:0003690 | 1.41457374128e-05 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | double-stranded DNA binding |
|   WP:WP5373 | 3.08046117151e-05 | 0.190476190476 | JUN FOSB FOS JUND | Role of hypoxia angiogenesis and FGF pathway in OA chondrocyte hypertrophy |
|   GO:0051171 | 5.65707914336e-05 | 0.904761904762 | TRIB2 EGR1 ATF7 CEBPG BATF3 ETV5 TRIB1 FOSB JUND DET1 WASHC1 ETV1 ATF3 COP1 UBE2E1 CREB5 BACH2 FOS JUN | regulation of nitrogen compound metabolic process |
|   CORUM:6092 | 6.82792716788e-05 | 0.0952380952381 | ATF3 JUN | c-Jun-ATF3 complex |
|   CORUM:2694 | 6.82792716788e-05 | 0.0952380952381 | FOS JUN | ERG-JUN-FOS DNA-protein complex |
|   CORUM:2693 | 6.82792716788e-05 | 0.0952380952381 | FOS JUN | NFAT-JUN-FOS DNA-protein complex |
|   CORUM:2695 | 6.82792716788e-05 | 0.0952380952381 | FOS JUN | ETS2-FOS-JUN complex |
|   KEGG:05031 | 6.95764128482e-05 | 0.190476190476 | CREB5 FOSB FOS JUN | Amphetamine addiction |
|   REAC:R-HSA-187037 | 6.95880741409e-05 | 0.238095238095 | TRIB1 EGR1 FOSB FOS JUND | Signaling by NTRK1 (TRKA) |
|   WP:WP366 | 7.40808356233e-05 | 0.238095238095 | ATF3 JUN FOSB FOS JUND | TGF beta signaling pathway |
|   GO:0080090 | 8.8917738812e-05 | 0.904761904762 | TRIB2 EGR1 ATF7 CEBPG BATF3 ETV5 TRIB1 FOSB JUND DET1 WASHC1 ETV1 ATF3 COP1 UBE2E1 CREB5 BACH2 FOS JUN | regulation of primary metabolic process |
|   REAC:R-HSA-166520 | 0.000156067232589 | 0.238095238095 | TRIB1 EGR1 FOSB FOS JUND | Signaling by NTRKs |
|   GO:0140110 | 0.000157251523294 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | transcription regulator activity |
|   GO:0051173 | 0.000184601441361 | 0.714285714286 | TRIB2 EGR1 ATF7 ETV1 TRIB1 JUND DET1 CEBPG ETV5 ATF3 COP1 UBE2E1 CREB5 FOS JUN | positive regulation of nitrogen compound metabolic process |
|   CORUM:6235 | 0.000204660259961 | 0.0952380952381 | FOS JUN | c-Fos-c-Jun-SAF-1 complex |
|   KEGG:04657 | 0.000233960398763 | 0.190476190476 | JUN FOSB FOS JUND | IL-17 signaling pathway |
|   GO:0006357 | 0.000240184465735 | 0.666666666667 | EGR1 ATF7 BATF3 BACH2 UBE2E1 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | regulation of transcription by RNA polymerase II |
|   GO:0005694 | 0.000257699802441 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | chromosome |
|   KEGG:04928 | 0.000315923666062 | 0.190476190476 | CREB5 EGR1 FOS JUND | Parathyroid hormone synthesis, secretion and action |
|   GO:0060255 | 0.000325860891678 | 0.904761904762 | TRIB2 EGR1 ATF7 CEBPG BATF3 ETV5 TRIB1 FOSB JUND DET1 WASHC1 ETV1 ATF3 COP1 UBE2E1 CREB5 BACH2 FOS JUN | regulation of macromolecule metabolic process |
|   CORUM:2692 | 0.000408965737855 | 0.0952380952381 | FOS JUN | SMAD3-SMAD4-cJun-cFos complex |
|   CORUM:2754 | 0.000408965737855 | 0.0952380952381 | JUND FOSB | JUND-FOSB-SMAD3-SMAD4 complex |
|   GO:0006366 | 0.000484123256313 | 0.666666666667 | EGR1 ATF7 BATF3 BACH2 UBE2E1 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | transcription by RNA polymerase II |
|   GO:0035976 | 0.000510886175237 | 0.142857142857 | JUN FOS JUND | transcription factor AP-1 complex |
|   GO:0003677 | 0.000620883784967 | 0.619047619048 | EGR1 ATF7 BATF3 BACH2 CEBPG ETV1 JUND ETV5 ATF3 CREB5 FOSB FOS JUN | DNA binding |
|   CORUM:1214 | 0.000681018805949 | 0.0952380952381 | COP1 DET1 | Ubiquitin E3 ligase (DET1, DDB1, CUL4A, RBX1, COP1) |
|   GO:0005667 | 0.000943754776813 | 0.380952380952 | ATF7 BATF3 JUND CEBPG BACH2 ATF3 FOS JUN | transcription regulator complex |
|   GO:0006355 | 0.000964495488023 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of DNA-templated transcription |
|   GO:2001141 | 0.00104964828297 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of RNA biosynthetic process |
|   GO:0010604 | 0.00105598828541 | 0.714285714286 | TRIB2 EGR1 ATF7 ETV1 TRIB1 JUND DET1 CEBPG ETV5 ATF3 COP1 UBE2E1 CREB5 FOS JUN | positive regulation of macromolecule metabolic process |
|   KEGG:04380 | 0.00115358871983 | 0.190476190476 | JUN FOSB FOS JUND | Osteoclast differentiation |
|   GO:0045944 | 0.00144381866785 | 0.47619047619 | ATF7 EGR1 UBE2E1 JUND ETV1 CEBPG ETV5 ATF3 FOS JUN | positive regulation of transcription by RNA polymerase II |
|   GO:0019222 | 0.00153558711909 | 0.904761904762 | TRIB2 EGR1 ATF7 CEBPG BATF3 ETV5 TRIB1 FOSB JUND DET1 WASHC1 ETV1 ATF3 COP1 UBE2E1 CREB5 BACH2 FOS JUN | regulation of metabolic process |
|   GO:0001228 | 0.00153608090433 | 0.333333333333 | EGR1 CEBPG ETV1 ETV5 ATF3 FOS JUN | DNA-binding transcription activator activity, RNA polymerase II-specific |
|   KEGG:05030 | 0.00154611199491 | 0.142857142857 | CREB5 JUN FOSB | Cocaine addiction |
|   GO:0001216 | 0.00176709486089 | 0.333333333333 | EGR1 CEBPG ETV1 ETV5 ATF3 FOS JUN | DNA-binding transcription activator activity |
|   WP:WP3527 | 0.0018265004688 | 0.142857142857 | EGR1 BATF3 FOSB | Pre implantation embryo |
|   GO:0006351 | 0.00186924747106 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | DNA-templated transcription |
|   KEGG:04120 | 0.00216725659497 | 0.190476190476 | UBE2E1 COP1 DET1 UBE2E2 | Ubiquitin mediated proteolysis |
|   GO:0032774 | 0.00216919099625 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | RNA biosynthetic process |
|   GO:0045893 | 0.00227765378914 | 0.52380952381 | EGR1 ATF7 ETV1 UBE2E1 JUND CEBPG ETV5 ATF3 CREB5 FOS JUN | positive regulation of DNA-templated transcription |
|   GO:1902680 | 0.00234584164441 | 0.52380952381 | EGR1 ATF7 ETV1 UBE2E1 JUND CEBPG ETV5 ATF3 CREB5 FOS JUN | positive regulation of RNA biosynthetic process |
|   GO:0005634 | 0.00289795525695 | 0.952380952381 | TRIB2 EGR1 JUN STK40 BATF3 BACH2 TRIB1 JUND ATF7 DET1 ETV1 CEBPG ETV5 ATF3 COP1 UBE2E1 CREB5 FOSB FOS UBE2E2 | nucleus |
|   GO:0009893 | 0.0036629100287 | 0.714285714286 | TRIB2 EGR1 ATF7 ETV1 TRIB1 JUND DET1 CEBPG ETV5 ATF3 COP1 UBE2E1 CREB5 FOS JUN | positive regulation of metabolic process |
|   GO:0051252 | 0.00457278392266 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of RNA metabolic process |
|   WP:WP437 | 0.00583363045719 | 0.190476190476 | JUN FOSB FOS JUND | EGF EGFR signaling pathway |
|   WP:WP2374 | 0.00702589147166 | 0.142857142857 | EGR1 FOS JUND | Oncostatin M signaling pathway |
|   GO:0035497 | 0.00712601113833 | 0.142857142857 | CREB5 JUN ATF7 | cAMP response element binding |
|   GO:0051254 | 0.00737749042764 | 0.52380952381 | EGR1 ATF7 ETV1 UBE2E1 JUND CEBPG ETV5 ATF3 CREB5 FOS JUN | positive regulation of RNA metabolic process |
|   GO:0140467 | 0.0090039927973 | 0.190476190476 | JUN CEBPG BATF3 FOS | integrated stress response signaling |
|   REAC:R-HSA-9018519 | 0.00930250052112 | 0.190476190476 | JUN FOSB FOS JUND | Estrogen-dependent gene expression |
|   KEGG:05166 | 0.00959219990121 | 0.190476190476 | CREB5 JUN FOS EGR1 | Human T-cell leukemia virus 1 infection |
|   KEGG:05235 | 0.0114946357645 | 0.142857142857 | JUN BATF3 FOS | PD-L1 expression and PD-1 checkpoint pathway in cancer |
|   GO:0034654 | 0.0123003992036 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | nucleobase-containing compound biosynthetic process |
|   WP:WP2840 | 0.0129559957442 | 0.142857142857 | FOSB FOS JUN | Hair follicle development cytodifferentiation part 3 of 3 |
|   GO:0018130 | 0.0157948907324 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | heterocycle biosynthetic process |
|   WP:WP4919 | 0.0158065007671 | 0.0952380952381 | FOS JUN | Neuroinflammation |
|   GO:0019438 | 0.0160264121186 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | aromatic compound biosynthetic process |
|   GO:0019219 | 0.0161042757823 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of nucleobase-containing compound metabolic process |
|   KEGG:04915 | 0.0173756572637 | 0.142857142857 | CREB5 FOS JUN | Estrogen signaling pathway |
|   GO:0010468 | 0.0180267439011 | 0.761904761905 | TRIB2 EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of gene expression |
|   KEGG:04668 | 0.0190985543679 | 0.142857142857 | CREB5 FOS JUN | TNF signaling pathway |
|   WP:WP2355 | 0.0198445163578 | 0.142857142857 | FOSB FOS JUND | Corticotropin releasing hormone signaling pathway |
|   WP:WP4928 | 0.0217560686576 | 0.0952380952381 | FOS JUN | MAPK pathway in congenital thyroid cancer |
|   WP:WP2435 | 0.0217560686576 | 0.0952380952381 | FOS JUN | Quercetin and Nf kB AP 1 induced apoptosis |
|   GO:1901362 | 0.0238100531388 | 0.714285714286 | EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | organic cyclic compound biosynthetic process |
|   KEGG:04926 | 0.0278333210506 | 0.142857142857 | CREB5 FOS JUN | Relaxin signaling pathway |
|   REAC:R-HSA-450341 | 0.0281661174121 | 0.0952380952381 | FOS JUN | Activation of the AP-1 family of transcription factors |
|   GO:0010556 | 0.0283956554654 | 0.761904761905 | TRIB2 EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of macromolecule biosynthetic process |
|   GO:0045935 | 0.0284885882386 | 0.52380952381 | EGR1 ATF7 ETV1 UBE2E1 JUND CEBPG ETV5 ATF3 CREB5 FOS JUN | positive regulation of nucleobase-containing compound metabolic process |
|   WP:WP516 | 0.0364523199885 | 0.0952380952381 | JUND ATF3 | Hypertrophy model |
|   GO:0031326 | 0.0391185136275 | 0.761904761905 | TRIB2 EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of cellular biosynthetic process |
|   REAC:R-HSA-8939211 | 0.0402798139648 | 0.190476190476 | JUN FOSB FOS JUND | ESR-mediated signaling |
|   GO:0009889 | 0.042631852165 | 0.761904761905 | TRIB2 EGR1 ATF7 BATF3 BACH2 TRIB1 CEBPG ETV1 JUND ETV5 ATF3 UBE2E1 CREB5 FOSB FOS JUN | regulation of biosynthetic process |
|   WP:WP712 | 0.0451892186292 | 0.0952380952381 | FOS JUN | Estrogen signaling pathway |
|   WP:WP1528 | 0.0499027296991 | 0.0952380952381 | FOS JUN | Physiological and pathological hypertrophy of the heart |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
|  COP1 |  TRIB1 | 1.0 |            |
structurally_consistent (dimer)        
|
|  EEF1D |  VARS1 | 1.0 |            |          |
|  JUNB |  ATF7 | 1.0 | 0.136           |          |
|  FOS |  JUND | 1.0 |            |          |
|  DET1 |  TRIB1 | 1.0 |            |
structurally_consistent (Q92519)        
|
|  ATF2 |  JUNB | 1.0 | 0.094           |          |
|  JUNB |  JUN | 1.0 | 0.326120260424           |          |
|  STK40 |  DET1 | 0.999 |            |          |
|  FOS |  JUNB | 0.999 |            |          |
|  CREB5 |  JUN | 0.999 |            |          |
|  DET1 |  COP1 | 0.999 |            |
structurally_consistent (dimer)        
|
|  ATF7 |  JUN | 0.999 | 0.444           |          |
|  JUNB |  FOSL2 | 0.999 | 0.106           |
mutually_exclusive (P18847)        
|
|  COP1 |  JUNB | 0.999 | 0.068           |          |
|  DET1 |  UBE2E2 | 0.999 |            |
structurally_consistent (dimer)        
|
|  UBE2E1 |  DET1 | 0.999 |            |
structurally_consistent (Q92519)        
structurally_consistent (dimer)         |
|  FOSB |  JUNB | 0.999 |            |          |
|  COP1 |  JUN | 0.999 | 0.238           |          |
|  ATF7 |  FOSL2 | 0.999 | 0.112           |          |
|  ETV5 |  COP1 | 0.999 |            |          |
|  JUN |  FOSL2 | 0.999 | 0.32           |          |
|  ATF2 |  JUN | 0.999 | 0.376827743417           |          |
|  CREB5 |  JUNB | 0.999 |            |          |
|  JUND |  JUN | 0.998 | 0.45           |          |
|  ETV1 |  COP1 | 0.998 |            |          |
|  JUND |  ATF7 | 0.998 | 0.126           |          |
|  JUND |  FOSL2 | 0.998 | 0.174           |          |
|  STK40 |  TRIB1 | 0.998 |            |          |
|  BATF3 |  JUN | 0.998 |            |
structurally_consistent (dimer)        
|
|  JUNB |  JUND | 0.998 | 0.076           |          |
|  FOS |  JUN | 0.998 |            |          |
|  ATF2 |  JUND | 0.998 | 0.104           |          |
|  TRIB2 |  TRIB1 | 0.998 |            |
structurally_consistent (dimer)        
|
|  DET1 |  TRIB2 | 0.998 |            |
structurally_consistent (dimer)        
|
|  FOS |  ATF2 | 0.998 |            |          |
|  FOSL1 |  JUNB | 0.998 | 0.156           |          |
|  CREB5 |  JUND | 0.998 |            |          |
|  TRIB2 |  COP1 | 0.998 |            |
structurally_consistent (Q96RU8)        
|
|  ATF2 |  ATF7 | 0.997 | 0.244           |          |
|  COP1 |  JUND | 0.997 | 0.088           |          |
|  STK40 |  TRIB2 | 0.997 |            |          |
|  BATF3 |  JUND | 0.997 |            |
structurally_consistent (dimer)        
|
|  BATF3 |  ATF2 | 0.997 |            |
structurally_consistent (dimer)        
|
|  BATF3 |  ATF7 | 0.997 |            |
structurally_consistent (dimer)        
|
|  BATF3 |  JUNB | 0.997 |            |
structurally_consistent (dimer)        
|
|  STK40 |  ETV5 | 0.996 |            |          |
|  FOSL1 |  ATF2 | 0.996 | 0.094           |          |
|  ATF3 |  JUN | 0.996 | 0.261319148936           |          |
|  ETV5 |  DET1 | 0.995 |            |          |
|  COP1 |  FOSL1 | 0.995 | 0.132           |          |
|  FOSL1 |  JUND | 0.995 | 0.152           |
mutually_exclusive (Q9NR55)        
|
|  CREB5 |  ATF7 | 0.995 |            |          |
|  ATF2 |  CREB5 | 0.995 |            |          |
|  UBE2E1 |  TRIB1 | 0.995 |            |          |
|  FOSL1 |  JUN | 0.995 | 0.367002881844           |          |
|  FOSL1 |  ATF7 | 0.995 | 0.214           |          |
|  STK40 |  ETV1 | 0.994 |            |          |
|  TRIB1 |  FOSL2 | 0.994 |            |          |
|  COP1 |  ATF7 | 0.992 | 0.15           |          |
|  TRIB1 |  FOS | 0.992 |            |          |
|  FOSB |  JUN | 0.991 |            |          |
|  STK40 |  COP1 | 0.991 |            |          |
|  STK40 |  FOS | 0.991 |            |          |
|  TRIB1 |  JUNB | 0.991 |            |          |
|  ATF3 |  FOSL2 | 0.99 | 0.114           |
structurally_consistent (dimer)        
|
|  COP1 |  FOS | 0.99 |            |          |
|  ATF2 |  FOSL2 | 0.989 | 0.092           |          |
|  DET1 |  ETV1 | 0.988 |            |          |
|  COP1 |  FOSL2 | 0.988 | 0.122           |          |
|  VARS1 |  JUND | 0.988 | 0.156           |          |
|  VARS1 |  ATF7 | 0.986 | 0.088           |          |
|  FOSB |  JUND | 0.986 |            |          |
|  CREB5 |  ATF3 | 0.986 |            |          |
|  EEF1D |  BATF3 | 0.986 |            |
structurally_consistent (dimer)        
|
|  VARS1 |  ATF2 | 0.985 | 0.114           |          |
|  FOSB |  ATF2 | 0.985 |            |          |
|  STK40 |  FOSL2 | 0.985 |            |          |
|  FOSB |  ATF7 | 0.983 |            |          |
|  VARS1 |  JUNB | 0.982 | 0.12           |          |
|  JUNB |  ATF3 | 0.982 | 0.1444           |
structurally_consistent (dimer)        
|
|  STK40 |  FOSL1 | 0.981 |            |          |
|  UBE2E1 |  TRIB2 | 0.978 |            |
structurally_consistent (dimer)        
|
|  EEF1D |  JUNB | 0.978 |            |
mutually_exclusive (Q9NR55)        
|
|  UBE2E1 |  STK40 | 0.976 |            |          |
|  STK40 |  JUND | 0.975 |            |          |
|  DET1 |  FOS | 0.975 |            |
structurally_consistent (dimer)        
|
|  CREB5 |  FOSL2 | 0.974 |            |          |
|  COP1 |  ATF2 | 0.973 | 0.15           |          |
|  ATF2 |  ATF3 | 0.972 | 0.08           |          |
|  ATF7 |  ATF3 | 0.971 | 0.092           |          |
|  EEF1D |  JUND | 0.97 |            |
mutually_exclusive (Q9NR55)        
|
|  STK40 |  ATF2 | 0.969 |            |          |
|  FOS |  ATF7 | 0.969 |            |          |
|  EEF1D |  ATF7 | 0.968 |            |
mutually_exclusive (Q9NR55)        
|
|  VARS1 |  FOSL2 | 0.968 | 0.172           |          |
|  STK40 |  JUNB | 0.967 |            |          |
|  DET1 |  FOSL2 | 0.965 |            |          |
|  VARS1 |  BATF3 | 0.964 |            |          |
|  FOSB |  TRIB1 | 0.96 |            |          |
|  BATF3 |  CREB5 | 0.957 |            |
structurally_consistent (dimer)        
|
|  TRIB1 |  FOSL1 | 0.957 |            |          |
|  EEF1D |  FOSL1 | 0.956 |            |
mutually_exclusive (Q9NR55)        
|
|  UBE2E1 |  COP1 | 0.955 | 0.094           |          |
|  FOSB |  COP1 | 0.954 |            |          |
|  CREB5 |  CEBPG | 0.952 |            |          |
|  STK40 |  ATF7 | 0.949 |            |          |
|  STK40 |  JUN | 0.946 |            |          |
|  TRIB1 |  JUND | 0.946 |            |          |
|  EEF1D |  CEBPG | 0.944 |            |          |
|  FOSB |  STK40 | 0.943 |            |          |
|  BATF3 |  BACH2 | 0.94 |            |
structurally_consistent (dimer)        
|
|  COP1 |  UBE2E2 | 0.936 | 0.122           |
mutually_exclusive (Q7L5Y6)        
|
|  EEF1D |  JUN | 0.932 |            |
mutually_exclusive (Q9NR55)        
|
|  VARS1 |  CEBPG | 0.932 |            |
structurally_consistent (dimer)        
|
|  EEF1D |  FOSL2 | 0.93 |            |          |
|  TRIB1 |  JUN | 0.929 |            |          |
|  VARS1 |  JUN | 0.927 | 0.516           |          |
|  TRIB1 |  ATF7 | 0.924 |            |          |
|  DET1 |  JUNB | 0.92 |            |          |
|  VARS1 |  FOSL1 | 0.912 | 0.217           |          |
|  TRIB1 |  ATF2 | 0.906 |            |          |
|  ETV5 |  ETV1 | 0.902 |            |          |
|  ETV5 |  UBE2E2 | 0.902 |            |          |
|  ETV1 |  UBE2E2 | 0.902 |            |          |
|  FOSL1 |  FOSL2 | 0.902 | 0.184           |          |
|  BACH2 |  FOSL2 | 0.898 |            |          |
|  EEF1D |  ATF2 | 0.894 |            |
mutually_exclusive (Q9NR55)        
|
|  ATF7 |  CEBPG | 0.894 |            |          |
|  FOS |  CREB5 | 0.892 |            |          |
|  BACH2 |  CREB5 | 0.89 |            |
mutually_exclusive (Q9NR55)        
|
|  FOSB |  CREB5 | 0.877 |            |          |
|  EGR1 |  FOSL2 | 0.876 |            |          |
|  COP1 |  WASHC1 | 0.873 |            |          |
|  VARS1 |  CREB5 | 0.872 |            |          |
|  EGR1 |  JUND | 0.86 |            |          |
|  JUN |  CEBPG | 0.859 |            |          |
|  EEF1D |  CREB5 | 0.854 |            |
mutually_exclusive (Q9NR55)        
|
|  VARS1 |  FOS | 0.853 |            |          |
|  FOSL1 |  CREB5 | 0.848 |            |          |
|  BACH2 |  ATF7 | 0.843 |            |
mutually_exclusive (Q9NR55)        
|
|  VARS1 |  COP1 | 0.838 | 0.2758           |          |
|  VARS1 |  STK40 | 0.835 |            |          |
|  VARS1 |  TRIB1 | 0.822 |            |          |
|  EGR1 |  JUNB | 0.816 |            |          |
|  BACH2 |  ATF2 | 0.816 |            |
mutually_exclusive (Q9NR55)        
|
|  COP1 |  ETS2 | 0.814 |            |          |
|  UBE2E1 |  UBE2E2 | 0.787 | 0.102           |
structurally_consistent (Q7L5Y6)        
|
|  JUND |  CEBPG | 0.745 |            |          |
|  STK40 |  UBE2E2 | 0.733 |            |          |
|  EEF1D |  FOS | 0.678 |            |          |
|  COP1 |  CREB5 | 0.644 |            |          |
|  TRIB1 |  UBE2E2 | 0.634 |            |          |
|  STK40 |  CREB5 | 0.595 |            |          |
|  VARS1 |  DET1 | 0.569 |            |          |
|  BACH2 |  JUN | 0.525 |            |
mutually_exclusive (Q9NR55)        
|
|  FOSB |  FOSL2 | 0.502 |            |          |
|  BATF3 |  FOSB | 0.502 |            |          |
|  BATF3 |  FOSL2 | 0.502 |            |          |
|  ATF2 |  CEBPG | 0.489 |            |          |
|  FOSB |  ATF3 | 0.487 |            |          |
|  DET1 |  JUND | 0.447 |            |          |
|  ETV5 |  TRIB1 | 0.418 |            |          |
|  ETV1 |  TRIB1 | 0.418 |            |          |
|  TRIB1 |  CREB5 | 0.389 |            |          |
|  DET1 |  CREB5 | 0.367 |            |          |
|  DET1 |  JUN | 0.363 |            |          |
|  DET1 |  ATF2 | 0.359 |            |          |
|  DET1 |  ATF7 | 0.359 |            |          |
|  UBE2E1 |  ETV5 | 0.356 |            |          |
|  UBE2E1 |  ETV1 | 0.356 |            |          |
|  BATF3 |  ATF3 | 0.333 |            |
structurally_consistent (dimer)        
|
|  BACH2 |  JUND | 0.281 |            |
mutually_exclusive (Q9NR55)        
|
|  VARS1 |  FOSB | 0.25 |            |          |
|  EEF1D |  BACH2 | 0.23 |            |
mutually_exclusive (Q9NR55)        
|
|  BACH2 |  JUNB | 0.23 |            |          |
|  VARS1 |  BACH2 | 0.23 |            |          |
|  BATF3 |  FOSL1 | 0.214 |            |
structurally_consistent (dimer)        
|
|  FOSB |  FOSL1 | 0.214 |            |          |
|  EEF1D |  TRIB1 | 0.207 |            |          |
|  TRIB1 |  BACH2 | 0.206 |            |          |
|  COP1 |  ATF3 | 0.198 | 0.148           |          |
|  DET1 |  BACH2 | 0.185 |            |          |
|  FOSB |  DET1 | 0.172 |            |          |
|  STK40 |  ATF3 | 0.165 |            |          |
|  DET1 |  ATF3 | 0.164 |            |          |
|  TRIB1 |  ATF3 | 0.164 |            |          |
|  JUND |  ATF3 | 0.164 | 0.126           |          |
|  EEF1D |  COP1 | 0.147 |            |          |
|  FOSL1 |  ATF3 | 0.146 | 0.118           |          |
|  BATF3 |  DET1 | 0.143 |            |          |
|  BATF3 |  TRIB1 | 0.143 |            |          |
|  BATF3 |  STK40 | 0.138 |            |          |
|  STK40 |  BACH2 | 0.116 |            |          |
|  BATF3 |  COP1 | 0.114 |            |          |
|  COP1 |  BACH2 | 0.108 |            |          |
|  EEF1D |  FOSB | 0.103 |            |          |
|  EEF1D |  STK40 | 0.096 |            |          |
|  ATF3 |  CEBPG | 0.079 |            |          |
|  EEF1D |  DET1 | 0.05 |            |          |
|  EEF1D |  ETV5 | 0.05 |            |          |
|  VARS1 |  ATF3 | 0.049 | 0.296           |          |
|  EEF1D |  ATF3 | 0.049 |            |
mutually_exclusive (Q9NR55)        
|
|  DET1 |  FOSL1 | 0.042 |            |          |
|  ETV5 |  JUN | 0.042 |            |          |
|  ETV1 |  JUN | 0.042 |            |          |
|  JUN |  UBE2E2 | 0.041 | 0.0950706150342           |          |
|  VARS1 |  UBE2E1 | 0.025 | 0.16           |          |
|  UBE2E1 |  FOSL1 | 0.018 | 0.064           |          |
|  EEF1D |  WASHC1 | 0.014 |            |          |
|  UBE2E1 |  JUND | 0.013 | 0.056           |          |
|  UBE2E1 |  JUNB | 0.013 | 0.034           |          |
|  UBE2E1 |  ATF2 | 0.013 | 0.068           |          |
|  UBE2E1 |  ATF7 | 0.013 | 0.094           |          |
|  EEF1D |  UBE2E1 | 0.013 |            |          |
|  UBE2E1 |  CREB5 | 0.011 |            |          |
|  EGR1 |  JUN | 0.011 |            |          |
|  UBE2E1 |  JUN | 0.01 | 0.310925266904           |          |
|  EGR1 |  WASHC1 | 0.009 |            |          |
|  UBE2E1 |  EGR1 | 0.008 |            |          |
|  VARS1 |  UBE2E2 | 0.005 | 0.108           |          |
|  EEF1D |  TRIB2 | 0.004 |            |          |
|  VARS1 |  EGR1 | 0.004 |            |          |
|  VARS1 |  TRIB2 | 0.003 |            |          |
|  EEF1D |  UBE2E2 | 0.002 |            |          |
|  EEF1D |  EGR1 | 0.002 |            |          |
|  UBE2E1 |  WASHC1 | 0.001 |            |          |
Related Complexes