hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_15286.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
INTS14	Integrator complex subunit 14 (von Willebrand factor A domain-containing protein 9)	4	UniProt NCBI
INTS11	Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)	5	UniProt NCBI
INTS13	Integrator complex subunit 13 (Cell cycle regulator Mat89Bb homolog) (Germ cell tumor 1) (Protein asunder homolog) (Sarcoma antigen NY-SAR-95)	5	UniProt NCBI
INTS6	Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1)	5	UniProt NCBI
TAS2R7	Taste receptor type 2 member 7 (T2R7) (Taste receptor family B member 4) (TRB4)	4	UniProt NCBI
INTS9	Integrator complex subunit 9 (Int9) (Protein related to CPSF subunits of 74 kDa) (RC-74)	5	UniProt NCBI
INTS4	Integrator complex subunit 4 (Int4)	5	UniProt NCBI
TCN2	Transcobalamin-2 (TC-2) (Transcobalamin II) (TC II) (TCII)	5	UniProt NCBI
INTS10	Integrator complex subunit 10 (Int10)	4	UniProt NCBI
ARL13A	ADP-ribosylation factor-like protein 13A	3	UniProt NCBI
PLEKHA5	Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)	5	UniProt NCBI
INTS12	Integrator complex subunit 12 (Int12) (PHD finger protein 22)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0032039	3.6206988023e-17	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	integrator complex
GO:0016180	7.47120768672e-16	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	snRNA processing
CORUM:1153	3.8327447653e-15	0.5	INTS12 INTS9 INTS10 INTS11 INTS6 INTS4	Integrator complex
CORUM:1155	7.11544801544e-15	0.5	INTS12 INTS9 INTS10 INTS11 INTS6 INTS4	Integrator-RNAPII complex
REAC:R-HSA-6807505	3.07608959098e-14	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	RNA polymerase II transcribes snRNA genes
GO:0016073	3.57608670482e-13	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	snRNA metabolic process
CORUM:1154	6.85202068216e-12	0.416666666667	INTS9 INTS10 INTS4 INTS11 INTS6	DSS1 complex
GO:0034243	1.10715031837e-11	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	regulation of transcription elongation by RNA polymerase II
GO:0032784	5.71576281166e-11	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	regulation of DNA-templated transcription elongation
GO:0006368	8.04260512926e-11	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	transcription elongation by RNA polymerase II
GO:0006354	2.97208860456e-10	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	DNA-templated transcription elongation
WP:WP5345	8.54902861772e-10	0.5	INTS4 INTS9 INTS10 INTS11 INTS13 INTS14	1p36 copy number variation syndrome
GO:0034470	2.32781074424e-06	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	ncRNA processing
GO:0034660	4.84890632588e-05	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	ncRNA metabolic process
GO:0034472	7.7374519929e-05	0.333333333333	INTS9 INTS12 INTS14 INTS6	snRNA 3'-end processing
REAC:R-HSA-73857	0.000139213139881	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	RNA Polymerase II Transcription
REAC:R-HSA-74160	0.000366136880285	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	Gene expression (Transcription)
GO:0006396	0.00113865950967	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	RNA processing
GO:0140513	0.0197270317597	0.666666666667	INTS4 INTS9 INTS10 INTS6 INTS11 INTS13 INTS14 INTS12	nuclear protein-containing complex
GO:0031123	0.0242643828416	0.333333333333	INTS9 INTS12 INTS14 INTS6	RNA 3'-end processing

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
INTS9	INTS11	1.0	0.91	hein_WMM bioplex3_HEK293 bioplex3_WMM Malo bioplex3_HCT116 fraction
INTS9	INTS4	1.0	0.414	hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction
INTS12	INTS4	1.0	0.614	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
INTS14	INTS10	0.999	0.12	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein ()
INTS11	INTS4	0.998	0.494	hein_WMM bioplex_WMM bioplex3_WMM hein () Malo fraction
INTS13	INTS10	0.997	0.184	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM
INTS13	INTS14	0.997	0.826	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo fraction
INTS6	INTS4	0.993	0.886	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein ()
INTS6	INTS11	0.99	0.56	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS6	INTS9	0.986	0.48	hein_WMM bioplex3_WMM WMM_only
INTS14	INTS6	0.959	0.264	hein_WMM bioplex_WMM bioplex3_WMM hein ()
INTS6	INTS12	0.954	0.48	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
INTS14	INTS11	0.952	0.236	hein_WMM bioplex_WMM bioplex3_WMM hein ()
INTS10	INTS4	0.946	0.618	hein_WMM youn_WMM WMM_only
INTS10	INTS9	0.946	0.4	hein_WMM youn_WMM WMM_only
INTS14	INTS4	0.945	0.442	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
PLEKHA5	INTS6	0.944	0.1	hein_WMM bioplex3_WMM WMM_only
INTS10	INTS12	0.944	0.236	hein_WMM youn_WMM WMM_only
INTS12	INTS9	0.936	0.564	hein_WMM youn_WMM WMM_only
INTS13	INTS4	0.929	0.446	hein_WMM youn_WMM Malo fraction
TCN2	INTS12	0.921		bioplex3_WMM bioplex3_HCT116 WMM_only
PLEKHA5	INTS9	0.901	0.072	hein_WMM bioplex3_WMM youn_WMM WMM_only
INTS14	INTS12	0.901	0.346	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
INTS12	TAS2R7	0.876		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
PLEKHA5	INTS12	0.873	0.046	hein_WMM bioplex_WMM youn_WMM WMM_only
INTS14	INTS9	0.872	0.396	hein_WMM youn_WMM hein ()
INTS12	INTS11	0.86	0.432	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS12	ARL13A	0.843		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
PLEKHA5	INTS11	0.832	0.026	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS10	INTS11	0.781	0.288	hein_WMM WMM_only
INTS10	INTS6	0.781	0.456	hein_WMM WMM_only
INTS13	INTS12	0.655	0.264	hein_WMM youn_WMM WMM_only
INTS13	INTS9	0.52	0.494	hein_WMM youn_WMM WMM_only
PLEKHA5	INTS4	0.518	0.024	hein_WMM youn_WMM WMM_only
INTS13	INTS6	0.425	0.376	hein_WMM bioplex3_WMM WMM_only
INTS13	INTS11	0.232	0.142	hein_WMM WMM_only
PLEKHA5	INTS14	0.006	0.016	youn_WMM WMM_only

Related Complexes

Genename	Complexes
INTS14	huMAP3_00628.1 huMAP3_12564.1 huMAP3_15286.1
INTS11	huMAP3_06382.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_15286.1
INTS13	huMAP3_00628.1 huMAP3_03028.1 huMAP3_11853.1 huMAP3_12564.1 huMAP3_14818.1 huMAP3_15286.1
INTS6	huMAP3_01810.1 huMAP3_04137.1 huMAP3_04823.1 huMAP3_06989.1 huMAP3_08147.1 huMAP3_08278.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_10684.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
TAS2R7	huMAP3_12564.1 huMAP3_12917.1 huMAP3_13805.1 huMAP3_15286.1
INTS9	huMAP3_05510.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS4	huMAP3_06382.1 huMAP3_06914.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
TCN2	huMAP3_00557.1 huMAP3_11275.1 huMAP3_12564.1 huMAP3_13956.1 huMAP3_15286.1
INTS10	huMAP3_00628.1 huMAP3_03028.1 huMAP3_11853.1 huMAP3_12564.1 huMAP3_14818.1 huMAP3_15286.1
ARL13A	huMAP3_12564.1 huMAP3_14910.1 huMAP3_15286.1
PLEKHA5	huMAP3_00539.1 huMAP3_01751.1 huMAP3_07673.1 huMAP3_10682.1 huMAP3_12564.1 huMAP3_15286.1
INTS12	huMAP3_04823.1 huMAP3_06382.1 huMAP3_06914.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10153.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_15286.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_15286.1