List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_15292.1

Confidence: Medium   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
HK2	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase)	5	UniProt   NCBI
CD3G	T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)	5	UniProt   NCBI
ZNF836	Zinc finger protein 836	3	UniProt   NCBI
ICMT	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)	5	UniProt   NCBI
PET100	Protein PET100 homolog, mitochondrial	4	UniProt   NCBI
HK1	Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) (Hexokinase-A)	5	UniProt   NCBI
GCK	Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D)	5	UniProt   NCBI
HK3	Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III) (Hexokinase-C)	5	UniProt   NCBI
HKDC1	Hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1)	5	UniProt   NCBI
PPM1E	Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:00524	1.67567435013e-11	0.444444444444	GCK HKDC1 HK2 HK3	Neomycin, kanamycin and gentamicin biosynthesis
GO:0004340	1.65724193228e-08	0.444444444444	GCK HKDC1 HK2 HK3	glucokinase activity
GO:0004396	1.65724193228e-08	0.444444444444	GCK HKDC1 HK2 HK3	hexokinase activity
GO:0008865	1.65724193228e-08	0.444444444444	GCK HKDC1 HK2 HK3	fructokinase activity
KEGG:00500	4.21629290299e-08	0.444444444444	GCK HKDC1 HK2 HK3	Starch and sucrose metabolism
KEGG:00052	4.98152615684e-08	0.444444444444	GCK HKDC1 HK2 HK3	Galactose metabolism
KEGG:01250	1.74040124874e-07	0.444444444444	GCK HKDC1 HK2 HK3	Biosynthesis of nucleotide sugars
KEGG:04930	3.36059361355e-07	0.444444444444	GCK HKDC1 HK2 HK3	Type II diabetes mellitus
KEGG:00520	4.93890189783e-07	0.444444444444	GCK HKDC1 HK2 HK3	Amino sugar and nucleotide sugar metabolism
GO:0046835	6.95089238983e-07	0.444444444444	GCK HKDC1 HK2 HK3	carbohydrate phosphorylation
WP:WP5394	1.76423910984e-06	0.333333333333	GCK HK2 HK3	UDP derived sugars synthesis in fibroblasts
KEGG:00010	1.84054410312e-06	0.444444444444	GCK HKDC1 HK2 HK3	Glycolysis / Gluconeogenesis
KEGG:05230	2.52544155751e-06	0.444444444444	GCK HKDC1 HK2 HK3	Central carbon metabolism in cancer
REAC:R-HSA-70171	1.04617214219e-05	0.444444444444	GCK HKDC1 HK2 HK3	Glycolysis
KEGG:01200	1.49968945505e-05	0.444444444444	GCK HKDC1 HK2 HK3	Carbon metabolism
GO:0019200	1.59928316967e-05	0.444444444444	GCK HKDC1 HK2 HK3	carbohydrate kinase activity
REAC:R-HSA-70326	2.31277665371e-05	0.444444444444	GCK HKDC1 HK2 HK3	Glucose metabolism
KEGG:04910	3.2447952468e-05	0.444444444444	GCK HKDC1 HK2 HK3	Insulin signaling pathway
GO:0051156	3.50368755955e-05	0.444444444444	GCK HKDC1 HK2 HK3	glucose 6-phosphate metabolic process
KEGG:00051	4.83882119138e-05	0.333333333333	HKDC1 HK2 HK3	Fructose and mannose metabolism
KEGG:04973	5.2908290519e-05	0.333333333333	HKDC1 HK2 HK3	Carbohydrate digestion and absorption
WP:WP500	0.000113287761665	0.333333333333	HKDC1 HK2 HK3	Glycogen synthesis and degradation
WP:WP534	0.000167122221162	0.333333333333	GCK HK2 HK3	Glycolysis and gluconeogenesis
KEGG:04066	0.00124312860357	0.333333333333	HKDC1 HK2 HK3	HIF-1 signaling pathway
WP:WP5355	0.00146973735431	0.333333333333	GCK HK2 HK3	Metabolic Epileptic Disorders
GO:0006096	0.00220742322002	0.444444444444	GCK HKDC1 HK2 HK3	glycolytic process
GO:0046032	0.00220742322002	0.444444444444	GCK HKDC1 HK2 HK3	ADP catabolic process
GO:0046031	0.00234919252133	0.444444444444	GCK HKDC1 HK2 HK3	ADP metabolic process
GO:0009181	0.00249766170037	0.444444444444	GCK HKDC1 HK2 HK3	purine ribonucleoside diphosphate catabolic process
GO:0009137	0.00249766170037	0.444444444444	GCK HKDC1 HK2 HK3	purine nucleoside diphosphate catabolic process
REAC:R-HSA-71387	0.0025623436403	0.444444444444	GCK HKDC1 HK2 HK3	Metabolism of carbohydrates
GO:0019364	0.00265303695292	0.444444444444	GCK HKDC1 HK2 HK3	pyridine nucleotide catabolic process
GO:0009179	0.00265303695292	0.444444444444	GCK HKDC1 HK2 HK3	purine ribonucleoside diphosphate metabolic process
GO:0001678	0.00281552750158	0.444444444444	GCK HKDC1 HK2 HK3	intracellular glucose homeostasis
GO:0009135	0.00281552750158	0.444444444444	GCK HKDC1 HK2 HK3	purine nucleoside diphosphate metabolic process
GO:0009191	0.00298534559142	0.444444444444	GCK HKDC1 HK2 HK3	ribonucleoside diphosphate catabolic process
GO:0072526	0.00316270648564	0.444444444444	GCK HKDC1 HK2 HK3	pyridine-containing compound catabolic process
GO:0009134	0.00334782846127	0.444444444444	GCK HKDC1 HK2 HK3	nucleoside diphosphate catabolic process
GO:0009185	0.00417039795891	0.444444444444	GCK HKDC1 HK2 HK3	ribonucleoside diphosphate metabolic process
GO:0006735	0.00450341440411	0.333333333333	GCK HK2 HK3	NADH regeneration
GO:0061621	0.00450341440411	0.333333333333	GCK HK2 HK3	canonical glycolysis
GO:0061718	0.00450341440411	0.333333333333	GCK HK2 HK3	glucose catabolic process to pyruvate
GO:0009132	0.0051353875679	0.444444444444	GCK HKDC1 HK2 HK3	nucleoside diphosphate metabolic process
GO:0061615	0.00546674693619	0.333333333333	GCK HK2 HK3	glycolytic process through fructose-6-phosphate
GO:0061620	0.00546674693619	0.333333333333	GCK HK2 HK3	glycolytic process through glucose-6-phosphate
GO:0019677	0.00655807506899	0.333333333333	GCK HK2 HK3	NAD catabolic process
GO:0006090	0.00755501568248	0.444444444444	GCK HKDC1 HK2 HK3	pyruvate metabolic process
GO:0006007	0.00778531456229	0.333333333333	GCK HK2 HK3	glucose catabolic process
GO:0009154	0.0090427452869	0.444444444444	GCK HKDC1 HK2 HK3	purine ribonucleotide catabolic process
GO:0009261	0.00986369871123	0.444444444444	GCK HKDC1 HK2 HK3	ribonucleotide catabolic process
GO:0006195	0.0116711805491	0.444444444444	GCK HKDC1 HK2 HK3	purine nucleotide catabolic process
GO:0072523	0.0137151687321	0.444444444444	GCK HKDC1 HK2 HK3	purine-containing compound catabolic process
KEGG:05131	0.0146549467572	0.333333333333	HKDC1 HK2 HK3	Shigellosis
GO:0016052	0.0148319287105	0.444444444444	GCK HKDC1 HK2 HK3	carbohydrate catabolic process
GO:0006006	0.0154150912184	0.444444444444	GCK HKDC1 HK2 HK3	glucose metabolic process
GO:0006734	0.0184449339515	0.333333333333	GCK HK2 HK3	NADH metabolic process
GO:0042593	0.0214652036821	0.444444444444	GCK HKDC1 HK2 HK3	glucose homeostasis
GO:0009166	0.0222326056689	0.444444444444	GCK HKDC1 HK2 HK3	nucleotide catabolic process
GO:0033500	0.0230202913566	0.444444444444	GCK HKDC1 HK2 HK3	carbohydrate homeostasis
GO:0019362	0.0255085593346	0.444444444444	GCK HKDC1 HK2 HK3	pyridine nucleotide metabolic process
GO:0046496	0.0255085593346	0.444444444444	GCK HKDC1 HK2 HK3	nicotinamide nucleotide metabolic process
GO:1901292	0.0263809026071	0.444444444444	GCK HKDC1 HK2 HK3	nucleoside phosphate catabolic process
GO:0072524	0.029131744151	0.444444444444	GCK HKDC1 HK2 HK3	pyridine-containing compound metabolic process
GO:0019320	0.029267276266	0.333333333333	GCK HK2 HK3	hexose catabolic process
GO:0019318	0.0352688611428	0.444444444444	GCK HKDC1 HK2 HK3	hexose metabolic process
GO:0046365	0.0359812030822	0.333333333333	GCK HK2 HK3	monosaccharide catabolic process
GO:0005996	0.0489603106588	0.444444444444	GCK HKDC1 HK2 HK3	monosaccharide metabolic process



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
HK2	HK1	0.999	0.306	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     boldt_WMM
HK3	HK2	0.998	0.132	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
GCK	HK3	0.997		bioplex3_WMM     bioplex3_HCT116     WMM_only
HK3	HK1	0.996	0.036	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
HK1	HKDC1	0.992	0.894	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
CD3G	HKDC1	0.981		bioplex3_WMM     bioplex3_HCT116     WMM_only
HK1	ICMT	0.971	0.052	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     boldt_WMM
HK3	HKDC1	0.962	0.082	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
CD3G	HK1	0.869		bioplex3_WMM     bioplex3_HCT116     WMM_only
HK1	PET100	0.846	0.066	boldt     WMM_only     boldt_WMM
ICMT	PET100	0.846	0.078	boldt     WMM_only     boldt_WMM
ZNF836	PET100	0.846		boldt     boldt_WMM     WMM_only
ICMT	PPM1E	0.811	0.058	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
GCK	HKDC1	0.427		bioplex3_WMM     WMM_only
HK2	ICMT	0.176	0.044	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     boldt_WMM
HK1	PPM1E	0.137	0.07	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
GCK	HK2	0.12		bioplex3_WMM     WMM_only
GCK	HK1	0.116		bioplex3_WMM     WMM_only
HK2	HKDC1	0.108	0.13	bioplex_WMM     bioplex3_WMM     WMM_only
ZNF836	ICMT	0.065		boldt     WMM_only     boldt_WMM
HK1	ZNF836	0.065		boldt     WMM_only     boldt_WMM
HK2	PPM1E	0.031	0.0641013333333	bioplex_WMM     bioplex3_WMM     WMM_only
HKDC1	ICMT	0.025	0.064	bioplex3_WMM     WMM_only
HK2	CD3G	0.018		bioplex3_WMM     bioplex3_HCT116     WMM_only
HKDC1	PPM1E	0.009	0.0551428571429	bioplex3_WMM     WMM_only
HK3	ICMT	0.007	0.034	bioplex3_WMM     WMM_only





Related Complexes

Genename	Complexes
HK2	huMAP3_02064.1 huMAP3_02978.1 huMAP3_06095.1 huMAP3_06698.1 huMAP3_08681.1 huMAP3_08804.1 huMAP3_09730.1 huMAP3_10023.1 huMAP3_10399.1 huMAP3_10665.1 huMAP3_15292.1
CD3G	huMAP3_02841.1 huMAP3_03913.1 huMAP3_10399.1 huMAP3_11415.1 huMAP3_15292.1
ZNF836	huMAP3_05418.1 huMAP3_11283.1 huMAP3_14236.1 huMAP3_15292.1 huMAP3_15293.1
ICMT	huMAP3_05784.1 huMAP3_06999.1 huMAP3_09592.1 huMAP3_15292.1
PET100	huMAP3_11283.1 huMAP3_14236.1 huMAP3_15292.1 huMAP3_15293.1
HK1	huMAP3_02978.1 huMAP3_08804.1 huMAP3_10399.1 huMAP3_11415.1 huMAP3_15292.1
GCK	huMAP3_00687.1 huMAP3_02978.1 huMAP3_06698.1 huMAP3_10399.1 huMAP3_14554.1 huMAP3_15292.1
HK3	huMAP3_00687.1 huMAP3_02064.1 huMAP3_02978.1 huMAP3_06698.1 huMAP3_10023.1 huMAP3_10399.1 huMAP3_14554.1 huMAP3_15292.1
HKDC1	huMAP3_03913.1 huMAP3_10399.1 huMAP3_11415.1 huMAP3_15292.1
PPM1E	huMAP3_15292.1