hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_15299.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CRTAC1 | Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC) | 5 | UniProt NCBI |
| ADAMTS18 | A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-) | 5 | UniProt NCBI |
| ADAMTS13 | A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease) | 5 | UniProt NCBI |
| B3GLCT | Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like) | 5 | UniProt NCBI |
| ADAMTSL1 | ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1) | 5 | UniProt NCBI |
| CFP | Properdin (Complement factor P) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5083635 | 2.30778193041e-12 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Defective B3GALTL causes PpS |
| REAC:R-HSA-5173214 | 3.07686692355e-12 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | O-glycosylation of TSR domain-containing proteins |
| REAC:R-HSA-3906995 | 1.68608422955e-10 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Diseases associated with O-glycosylation of proteins |
| REAC:R-HSA-5173105 | 3.90830436311e-09 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | O-linked glycosylation |
| REAC:R-HSA-3781865 | 2.64838246794e-08 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Diseases of glycosylation |
| REAC:R-HSA-5668914 | 3.5491033683e-07 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Diseases of metabolism |
| REAC:R-HSA-597592 | 0.00433380037126 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Post-translational protein modification |
| REAC:R-HSA-1643685 | 0.0108707096527 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Disease |
| REAC:R-HSA-392499 | 0.0215959266916 | 0.833333333333 | CFP ADAMTSL1 B3GLCT ADAMTS18 ADAMTS13 | Metabolism of proteins |
| HP:0000851 | 0.0226111656051 | 0.333333333333 | B3GLCT ADAMTSL1 | Congenital hypothyroidism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| B3GLCT | ADAMTS13 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| B3GLCT | CFP | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CFP | CRTAC1 | 0.971 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| B3GLCT | ADAMTS18 | 0.96 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| B3GLCT | ADAMTSL1 | 0.83 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| B3GLCT | CRTAC1 | 0.214 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes