hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_15333.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MBP | Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein) | 5 | UniProt NCBI |
| CNEP1R1 | Nuclear envelope phosphatase-regulatory subunit 1 (NEP1-R1) (Transmembrane protein 188) | 5 | UniProt NCBI |
| CDCA3 | Cell division cycle-associated protein 3 (Gene-rich cluster protein C8) (Trigger of mitotic entry protein 1) (TOME-1) | 4 | UniProt NCBI |
| CTDSPL | CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3) | 5 | UniProt NCBI |
| CTDSP2 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2) | 5 | UniProt NCBI |
| CTDSP1 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1) | 5 | UniProt NCBI |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard) | 5 | UniProt NCBI |
| FBXL22 | F-box and leucine-rich protein 22 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0008420 | 0.0001882019462 | 0.375 | CTDSPL CTDSP2 CTDSP1 | RNA polymerase II CTD heptapeptide repeat phosphatase activity |
| GO:0004722 | 0.000668834683502 | 0.5 | CTDSPL CTDNEP1 CTDSP2 CTDSP1 | protein serine/threonine phosphatase activity |
| GO:0140994 | 0.00300428100757 | 0.375 | CTDSPL CTDSP2 CTDSP1 | RNA polymerase II CTD heptapeptide repeat modifying activity |
| REAC:R-HSA-4419969 | 0.00433819320746 | 0.25 | CNEP1R1 CTDNEP1 | Depolymerization of the Nuclear Lamina |
| GO:0071595 | 0.0131096201623 | 0.25 | CNEP1R1 CTDNEP1 | Nem1-Spo7 phosphatase complex |
| GO:0004721 | 0.0229851818624 | 0.5 | CTDSPL CTDNEP1 CTDSP2 CTDSP1 | phosphoprotein phosphatase activity |
| GO:0006470 | 0.0351826169143 | 0.5 | CNEP1R1 CTDNEP1 CTDSP2 CTDSP1 | protein dephosphorylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CTDSP1 | CTDSPL | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSP2 | CTDSP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSP2 | CDCA3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSPL | CDCA3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSP1 | MBP | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSP1 | CDCA3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSPL | MBP | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CTDSP2 | CTDSPL | 0.992 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CDCA3 | CNEP1R1 | 0.991 | 0.076 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CTDSP2 | MBP | 0.967 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CDCA3 | CTDNEP1 | 0.939 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| CTDSP2 | CNEP1R1 | 0.902 | bioplex3_WMM WMM_only | |
| CTDSPL | CNEP1R1 | 0.902 | bioplex3_WMM WMM_only | |
| CTDSP1 | FBXL22 | 0.855 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CTDSPL | CTDNEP1 | 0.682 | bioplex_WMM bioplex3_WMM WMM_only | |
| CNEP1R1 | CTDNEP1 | 0.675 | 0.34 | bioplex3_WMM WMM_only |
| CDCA3 | MBP | 0.646 | 0.092 | bioplex3_WMM WMM_only |
| CTDSP1 | CTDNEP1 | 0.632 | bioplex_WMM bioplex3_WMM WMM_only | |
| CTDSP2 | CTDNEP1 | 0.575 | bioplex_WMM bioplex3_WMM WMM_only | |
| CTDSP1 | CNEP1R1 | 0.455 | bioplex3_WMM WMM_only |
Related Complexes